A5101598421- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Renal Transplantation Outcomes and Treatments
- Voice and Speech Disorders
- Organ Donation and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastrointestinal Tumor Research and Treatment
- Gastric Cancer Management and Outcomes
- SARS-CoV-2 and COVID-19 Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Transplantation: Methods and Outcomes
- Congenital Anomalies and Fetal Surgery
- Metabolism and Genetic Disorders
- Clinical Nutrition and Gastroenterology
- Gallbladder and Bile Duct Disorders
- melanin and skin pigmentation
- Blood groups and transfusion
- Phonetics and Phonology Research
- Salmonella and Campylobacter epidemiology
- Skin Protection and Aging
- Metastasis and carcinoma case studies
- Hepatitis C virus research
- Gut microbiota and health
Shanghai Jiao Tong University
2016-2025
Kunming University of Science and Technology
2022-2025
First People's Hospital of Yunnan Province
2022-2025
Renji Hospital
2016-2025
Ninth Hospital of Nanchang
2020-2023
Taishan University
2023
Shanghai University of Traditional Chinese Medicine
2009-2021
Wannan Medical College
2021
Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine
2020
Ruijin Hospital
2012-2019
Tumors are usually refractory to anti-cancer therapeutics under hypoxic conditions. However, the underlying molecular mechanism remains be elucidated. Our study intended identify hypoxia inducible lncRNAs and their biological function in gastric cancer (GC). Differentially expressed were determined by microarray analysis between GC cells exposed (1% O2) normoxia (21% for 24 h. The expression level of CBSLR was manipulated several cell lines perform analyses both vitro vivo. We identified a...
The activation of tumor-associated macrophages (TAMs) facilitates the progression gastric cancer (GC). Cell metabolism reprogramming has been shown to play a vital role in polarization TAMs. However, methionine function TAMs remains be explored.Monocytes/macrophages were isolated from peripheral blood, tumor tissues or normal healthy donors patients with GC. was evaluated both vivo analyses and vitro experiments. Pharmacological inhibition cycle modulation key metabolic genes employed, where...
HB is the most common liver malignancy in children. Giving rarity of research reporting outcomes LT for China, updated long-term data are needed. The primary objective was to evaluate transplantation HB. secondary assess clinical parameters that influence We retrospectively analyzed dataset a single-center cohort from RJ-SJTUM. Outcomes were OS and PFS. Cox proportional hazard models used estimate mortality adjusted HRs with 95% CIs. RJ-SJTUM has accounted 68.5% total cases China since 2019....
We investigated the overall situation of LT for BA in mainland China and analyzed their survival outcomes based on data from CLTR. Between January 1996 December 2013, 509 liver transplants were performed included this study. Patients' median age was 9.6 months (range: 4.8-175.2 months). KP previously 194 cases (38.1%). Grafts living donors used 380 (74.7%). Era I (1996.1-2010.12) era II (2011.1-2013.12) comprised 151 (29.7%) 358 (70.3%), respectively. Twenty-five centers had at least one...
Liuzijue Qigong (LQG), a kind of traditional Chinese health exercise (TCHE), is not only widely used to strengthen physical fitness and maintain psychological well-being in the elderly but has also been utilized help improve respiratory function. As support an important driving force for speech production, it logical postulate that LQG training method with 6 monosyllabic sounds, xū, hē, hū, sī, chuī, xī, can individuals (1) experience relaxing natural state (2) eliminate voice symptoms, (3)...
AIM:To compare the surgical outcomes between living-donor and deceased-donor liver transplantation in patients with hepatic carcinoma. METHODS:From January 2007 to December 2010, 257 pathologically confirmed carcinoma met eligibility criteria of study.Forty who underwent (LDLT) constituted LDLT group, deceaseddonor (DDLT) was performed 217 patients.Patients group were randomly matched (1:2) DDLT using a multivariate case-matched method, so 40 80 enrolled into study.We compared two groups...
Aims: The aim of this study is to explore the optimal surgical approach for gastrointestinal stromal tumors (GISTs) stomach in terms perioperative outcomes and long-term relapse-free survival. Methods: From January 2004 July 2011, 156 patients who underwent either laparoscopic (LAP group, n = 68) or open surgery (OPEN 88) were included final analysis following eligibility criteria. Results: Clinicopathological characteristics selected similar between two groups. LAP group was associated with...
CXC195 exhibits strong protective effects against neuronal apoptosis by exerting antioxidant activity. However, the pharmacological function of in cancer remains to be elucidated. The present study demonstrated that exhibited significant cytotoxic effects, and induced cell cycle arrest HepG2 human hepatocellular carcinoma (HCC) lines. Following treatment cells with 150 µΜ for 24 , viability apoptotic rate were assessed using an MTT assay Annexin V/propidium iodide staining followed flow...
We aimed to assess the impact of size mismatching between grafts and recipients on outcomes infants or small children after LDLT. Between October 2006 December 2014, 129 LDLT weighing no more than 8 kg were retrospectively analyzed. The entire cohort was categorized into three groups by GRWR: GRWR < 3.0% (group A, n = 38), ≤ 4.0% B, 61), ≥ C, 30). Baseline characteristics similar among C. Compared with A post-transplant alanine aminotransferase aspartate within seven days significantly...
To investigate COVID-19 vaccine coverage in immunosuppressed children, assess guardians' intention to vaccinate and determine reasons associated factors. In addition, we attempted capture the characteristics of them with Omicron. We obtained vaccination guardian acceptance among pediatric transplant recipients through a web-based questionnaire conducted from April 12 28, 2022, performed statistical analysis. Seven organ recipient children Omicron were also clinically analyzed. The three-dose...
The objective of this study was to evaluate the risk factors and survival outcomes biliary complications (BCs) after living donor liver transplantation (LDLT) based on our single-center experience. From 2007 2010, 112 adult patients were assessed. Forty-nine (43.8%) experienced at least one episode BCs, including stricture bile leak, occurring in 37.5% 16.1% patients, respectively. Multivariate analysis indicated that hepatic artery thrombosis (relative (RR), 5.692; 95% CI, 2.132 15.201; p <...
Abstract Amidst the COVID‐19 pandemic, uncertainty persists among caregivers regarding vaccination of pediatric liver transplant recipients (PLTRs). This study evaluates immunogenicity and safety in this vulnerable population. A cohort 30 PLTRs underwent sequential vaccinations with an inactivated SARS‐CoV‐2 vaccine followed by Ad5‐nCoV booster. We collected analyzed blood samples pre‐vaccination four weeks post‐vaccination to quantify antibody IGRA (IFN‐γ Release Assay) levels. also...
Objective The aim of this study was to assess serum levels presurgical α-fetoprotein (AFP) and carbohydrate antigen 19-9 (CA19-9) as prognostic markers in patients with hepatic carcinoma after liver transplantation (LT). Methods A total 226 were recruited for the analysis AFP CA19-9 levels, on basis which tumor marker type (TMT) defined evaluated prediction. Overall survival (OS) relapse-free (RFS) analyzed using Kaplan–Meier curves, univariate multivariate Cox models. Results One-year...
Vaccination is the best way to protect children under 5 years from death or disability. Children with biliary atresia (BA), which most common pediatric cholestatic end-stage liver disease (PELD), are more vulnerable infectious diseases. However, vaccination coverage and factors modulating vaccine responses in BA largely unknown.In this study, 288 (median age: 7 months) diagnosed before transplantation were enrolled for evaluation of status affecting immune response hepatitis B (HBV) vaccine....