A5100375011- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Sperm and Testicular Function
- Ovarian function and disorders
- Intracerebral and Subarachnoid Hemorrhage Research
- Reproductive Biology and Fertility
- Ultrasound in Clinical Applications
- Respiratory viral infections research
- Traumatic Brain Injury and Neurovascular Disturbances
- Ovarian cancer diagnosis and treatment
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Estrogen and related hormone effects
- Homicide, Infanticide, and Child Abuse
- Testicular diseases and treatments
- Mind wandering and attention
- Neurosurgical Procedures and Complications
- Monoclonal and Polyclonal Antibodies Research
- PI3K/AKT/mTOR signaling in cancer
- Intestinal and Peritoneal Adhesions
- Genetic Syndromes and Imprinting
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Assisted Reproductive Technology and Twin Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Ferroptosis and cancer prognosis
Southern Medical University
2011-2024
Zhujiang Hospital
2022-2024
Nanfang Hospital
2016-2024
Guangzhou Medical University
2024
Jinan University
2022-2023
Health First
2023
Fujian Medical University
2023
Lanzhou University
2022
First Hospital of Lanzhou University
2022
Yunnan Academy of Agricultural Sciences
2021
Trastuzumab, a humanized antibody targeting HER2, exhibits remarkable therapeutic efficacy against HER2-positive gastric cancer. However, recurrent resistance presents revolutionary claims. Warburg effect and AKT signaling pathway was involved in the to trastuzumab. Our previous studies have demonstrated that overexpression of metastasis associated with colon cancer 1 (MACC1) predicted poor prognosis GC promoted tumor cells proliferation invasion. In this study, we found MACC1 significantly...
The aim of this study was to the features lung ultrasonography (LUS) in disease and evaluate usefulness LUS neonatal intensive care unit (NICU). All 3405 neonates included underwent an examination. Diagnoses were based on medical history, clinical manifestation, laboratory examination, signs chest radiography (CR) and/or computed tomography (CT). A single expert physician performed all examinations. There 2658 cases (78.9%) with 747 (21.9%) without disease. main as follows: absence A-lines,...
Abstract Background Increases in extravascular lung water (EVLW) can lead to respiratory failure. This study aimed investigate whether the B‐line score (BLS) was correlated with EVLW content determined by wet/dry ratio a rabbit model. Methods A total of 45 New Zealand rabbits were randomly assigned nine groups. Among animals, models various levels induced infusion different volumes warm sterile normal saline (NS) via endotracheal tube. The arterial blood gas, spontaneous rate, and PaO 2 /FiO...
In order to endow environmental protection features dentifrice, hydroxyapatite (HA) was added ordinary dentifrice. The effects on dentinal tubule occlusion and surface mineralization were compared after brushing dentine discs with dentifrice or without HA. two types of then 100 µg/ml hexavalent chromium cation (Cr6+) solution in evaluate their capacities adsorbing Cr6+ from water. Our results showed that the containing HA significantly better than occluding tubules a plugging rate greater...
Abstract Endometrial epithelial cells carry distinct cancer-associated alterations that may be more susceptible to endometriosis. Mouse models have shown overexpression of SIRT1 associated with oncogene activation contributes the pathogenesis endometriosis, but underlying reason remains elusive. Here, we used integrated systems biology analysis and found enrichment endometrial stromal fibroblasts in endometriosis their cellular abundance correlated negatively clinical specimens. Furthermore,...
Abstract Background: This study aims to assess the therapeutic effects of a well-known component (puerarin) obtained from Chinese herb root in patients with polycystic ovary syndrome (PCOS). Methods: Women premature ovarian failure (POF) were assigned obese group (body mass index [BMI] ≥24 kg/m 2 and waist hip ratio [WHR] >0.85) or non-obese (group 3, n = 21). Obese further randomly treatment 1, 15) control 15). All received standard (Diane-35, 1 tablet/d, orally, plus metformin, 1.5 g/d,...
To explore the experiences of patients with ectopic pregnancies delayed medical care, goals to promote timely access reduce subsequent physical and psychological impacts, provide recommendations for improved management pregnancies.
Previous lncRNA microarray screening found that the AC002454.1 gene was highly expressed in endometriosis (EMS), and these expression levels were correlated with cyclin-dependent kinase-6 (CDK6). This study investigated level correlation between CDK6 endometrium tissues influence of changes upon biological behavior eutopic endometrial cells. We confirmed mRNA protein ectopic tissue from patients EMS clearly correlated. In vitro, both positively regulated proliferation, migration invasion...
Endometriosis (EM) is associated with oxidative stress. Advanced oxidation protein products (AOPPs) are novel markers of stress, which serve an important role as inflammatory mediator in various chronic diseases. In order to examine the AOPPs infertile women EM, present study analyzed levels AOPPs, estradiol (E2) and progesterone (P4) follicular fluid (FF) 89 or without EM undergoing vitro fertilization (IVF). The AOPP concentration FF group was significantly higher when compared that...
Objective This study aimed to assess the impact of multimodal monitoring on predicting prognosis patients with spontaneous intracerebral hemorrhage (SICH) and examine feasibility using noninvasive near-infrared spectroscopy (NIRS) for clinical prognosis. Methods Clinical data 38 SICH who underwent surgery in Department Neurosurgery Shaanxi Provincial People’s Hospital from May 2022 December were retrospectively analyzed. The categorized into two groups based Glasgow Outcome Scale (GOS) 3...
Advanced oxidation protein products (AOPPs) are a family of oxidized compounds and could induce oxidative stress inflammatory lesion in various cells. The accumulation AOPPs was associated with female reproduction diseases such as PCOS, leiomyoma endometriosis. However, the relationship between endometrial cells is unclear. To explore effects accumulated on cells, we treated normal rats epithelial (rEECs) endometriosis model AOPP. Primary rEECs were collected from 8-weeks-old Wistar rats....
Abstract Objective Our study aimed to investigate the predictive value of intracranial pressure (ICP) and cerebral oxygen metabolism monitoring in postoperative prognosis patients with spontaneous intracerebral hemorrhage (SICH). Methods The clinical data 55 SICH treated by neurosurgery were analyzed retrospectively. These divided into two groups based on Glasgow Outcome Scale (GOS) scores, i.e., poor group (GOS I-III) good IV V). Next, ICP indexes, such as brain temperature (BT), perfusion...
Objective: To investigate the application of heparin-binding protein along with albumin (HBP+ALB) in evaluating severity community-acquired pneumonia (CAP) and compares it single HBP, white blood cells (WBCs), C-reactive (CRP), procalcitonin (PCT). Methods: A total 226 patients CAP admitted to Emergency Department Zhujiang Hospital, Southern Medical University, Guangdong, China, between March 1, 2021, 2022, were enrolled. The grouped into two groups: mild ( n =175) severe (sCAP)( =51)....
The aim of the present study was to identify differential pathways in uterine leiomyomata (UL) using a novel method based on protein-protein interaction networks and pathway analysis. were constructed by examining intersections Reactome database Search Tool for Retrieval Interacting Genes/proteins (STRING) (PPI) networks. Objective network defined as expressed genes (DEGs) associated with interactions identified STRING. Topological centrality (degree) analysis performed explore hub...
To study the association of level advanced oxidation protein products (AOPPs) in seminal plasma with teratospermia and outcome parameters vitro fertilization (IVF).We conducted a cross-sectional among 272 male patients receiving assisted reproduction treatment Center for Reproductive Medicine our hospital between October, 2018 March, 2019. The levels AOPPs reactive oxygen species (ROS), demographic data, sperm IVF were analyzed all patients. According to percentage sperms normal morphology,...
Abstract Background: Community-acquired pneumonia (CAP) has a high incidence rate and mortality. Heparin-binding protein (HBP) is correlated with the severity of CAP. Albumin (ALB) its prognosis. However, role HBP ALB together (HBP–ALB) in assessing CAP unclear. This study investigates correlation between HBP–ALB Methods: A total 91 patients admitted to Emergency Department Zhujiang Hospital, Southern Medical University, March 1, 2021 2022 were enrolled. The placed into two groups: mild...