Protein kinase C (PKC) modulates the function of capsaicin receptor transient potential vanilloid 1 (TRPV1). This modulation manifests as increased current when channel is activated by capsaicin. In addition, studies have suggested that phosphorylation PKC might directly gate channel, because PKC-activating phorbol esters induce TRPV1 currents in absence applied ligands. To test whether both and gates direct phosphorylation, we used sequencing to determine major sites on intracellular...

Person re-identification (Re-ID) is an important task in video surveillance which automatically searches and identifies people across different cameras. Despite the extensive Re-ID progress RGB cameras, few works have studied between infrared images, essentially a cross-modality problem widely encountered real-world scenarios. The key challenge lies two folds, i.e., lack of discriminative information to re-identify same person modalities, difficulty learn robust metric towards such...

The recently cloned vanilloid receptor subtype 1 (VR1) is a ligand-gated channel that activated by capsaicin, protons, and heat. We have attempted to develop dominant negative isoform targeting several mutations of VR1 at highly conserved amino acids or residues potential functional importance expressing the mutants in Chinese hamster ovary cells. Mutation three acid putative sixth transmembrane domain disrupts activation both capsaicin resiniferatoxin. binding site this mutant intact,...

Background: It is considered that the pathogenesis closely related to an excessive production of pro-inflammatory cytokines caused by bacterial toxins and imbalance between anti-inflammatory mediatorsMaterials Methods: This work investigates effect electro-acupuncturing (EA), at Zusanli point (ST36) on plasma cytokine release organ dysfunction their mechanism in conscious rats with endotoxin challenge.Results: EA points obviously lowered elevated levels TNF-α, attenuated changes parameters...

The motivation behind online consumption behavior is different from that of social behavior, and research lacking regarding the impact identification on e-commerce consumption. current examines influence identification, which perceived anonymity, intrinsic continuous purchasing behaviors retailing websites based self-determination theory. mediating role was also empirically tested a sample 661 frequent consumers using partial least squares approach. findings were: (1) Identification...

Consolidated server racks are quickly becoming the backbone of IT infrastructure for science, engineering, and business, alike. These servers still largely built organized as when they were distributed, individual entities. Given that many fields increasingly rely on analytics huge datasets, it makes sense to support flexible resource utilization across improve cost-effectiveness performance. We introduce Venice, a family data-center architectures builds strong communication substrate...

Cell lines derived from tumors engineered in the CNS offer promise as models of specific neuronal cell types. CAD cells are an unusual subclone a murine line tyrosine hydroxylase (TH) driven tumorigenesis, which undergoes reversible morphological differentiation on serum deprivation. Using single-cell electrophysiology we have examined properties ion channels expressed cells. Despite relatively low resting potentials, can be induced to fire robust action potentials when mildly artificially...

For the architecture community, reasonable simulation time is a strong requirement in addition to performance data accuracy. However, emerging big and AI workloads are too huge at binary size level prohibitively expensive run on cycle-accurate simulators. The concept of motif, which identified as class units computation performed initial or intermediate data, first step towards building proxy benchmark mimic real-world workloads. there no practical way construct based motifs help research....

A Competence Set, which is a Habitual Domain (HD), collection of knowledge and skills. We use these skills to solve problems. Based on the concept fuzzy set theory, this study proposes method find an optimal process expand one's competence set. This presents expansion order by directed graph, path at each stage can be found proposed model. model minimization form constrained max-product relation inequalities. With model, not only compound considered, but also levels acquired problem...

Big data is a term used to refer sets that are too large or complex for traditional data-processing application software adequately deal with. With the deep integration between information technology and education, researchers at home abroad have made great progress in field of big education. Nevertheless, comprehensive quantitative analysis emerging research trends topics has not yet been discovered. To reveal characteristics current status educational data, 2052 related papers from China...

Virtual clusters are the fundamental support of new generation virtual High Performance Computing (HPC) systems. As a high level system component, cluster is designed based on machine and network to provide executing environment for large-scale parallel applications. This paper proposes novel solution dynamic deployment customization Elastic Cluster (EVC). In this work, we clusters, such as OS images, topologies software. automatically configured with isolated networks (network address, DNS...

Abstract To explore the hotspots in area of Smart education China, 245 related articles form China National Knowledge Infrastructure (CKNI) were analyzed by visualization software CiteSpace. The results show that: (1) studies smart began 2003 while there sporadic papers published next ten years. There was an increasing trend year from 2013 to 2017 and number reached historical peak with 52 articles. Xianming Yang, Jiangsu Normal University E-Education Research topped lists contributing...

Event-related potentials (ERP) play an important role in the early detection of emotional arousal. Previous studies aesthetics have shown that positive component appearing around 200 ms after stimulus (P2) and larger late (LPC) are closely related to stage aesthetic judgment. We investigated temporal features facial judgment on basis by using ERP technique. Participants were instructed predict holistic face level based regions eyes, mouth, or nose. Behavioral results show score predictions...

In order to meet the application demand for informatization, intellectualization, real-time and visualization of chemical plan, this paper proposes a monitoring project based on Internet Things technology. project, with backing data acquisition, transmission, storage, analysis display in cloud architecture full use ZigBee, new wireless sensor network, visual system, which can be run multiple platforms, is constructed through synthetic actual requirements characteristics. This elaborates...

Environmental psychology is an interdisciplinary field that focuses on the interplay between individuals and their surroundings. Chinese researchers conducted extensive research produced a wealth of academic achievements, especially application environmental psychology, such as protection minority towns villages prevention solution air pollution. To reveal current situation researches in China, 388 related papers from China National Knowledge Infrastructure (CNKI) were analyzed by...