- Olfactory and Sensory Function Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Hearing Loss and Rehabilitation
- Photoacoustic and Ultrasonic Imaging
- Optical Imaging and Spectroscopy Techniques
- Advanced Chemical Sensor Technologies
- Surgical Simulation and Training
- Allergic Rhinitis and Sensitization
- Augmented Reality Applications
- Tumors and Oncological Cases
- Infrared Thermography in Medicine
- Biochemical Analysis and Sensing Techniques
- Medical Practices and Rehabilitation
- Anatomy and Medical Technology
- Autoimmune Neurological Disorders and Treatments
- Sinusitis and nasal conditions
- Ultrasound Imaging and Elastography
- Nasal Surgery and Airway Studies
- Laser Applications in Dentistry and Medicine
- Indoor and Outdoor Localization Technologies
- Head and Neck Surgical Oncology
- Vascular Tumors and Angiosarcomas
- Vascular Malformations and Hemangiomas
- Salivary Gland Tumors Diagnosis and Treatment
- Ear Surgery and Otitis Media
Charité - Universitätsmedizin Berlin
2014-2023
Humboldt-Universität zu Berlin
2019-2021
Freie Universität Berlin
2019-2021
University Medical Center Hamburg-Eppendorf
2012
Universität Hamburg
2012
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2007
We address the automatic differentiation of human tissue using multispectral imaging with promising potential for visualization during surgery. Currently, types have to be continuously differentiated based on surgeon's knowledge only. Further, methods optical in vivo properties do not yet exist, as these been sufficiently examined. To overcome this, we developed a hyperspectral camera setup monitor different behavior vivo. The aim this work is collect and analyze behaviors open up...
Existing challenges in surgical education (See one, do teach one) as well the COVID-19 pandemic make it necessary to develop new ways for training. Therefore, this work describes implementation of a scalable remote solution called "TeleSTAR" using immersive, interactive and augmented reality elements which enhances training operating room. The system uses full digital microscope context Ear-Nose-Throat surgery. is equipped with modular software interface consisting an annotation mode mark...
Abstract Introduction Endoscopic skull base approaches are broadly used in modern neurosurgery. The support of neuronavigation can help to effectively target the lesion avoiding complications. In children, endoscopic-assisted surgery combination with navigation systems becomes even more important because morphological variability and rare diseases affecting sellar parasellar regions. This paper aims analyze our first experience on augmented reality endoscopic a pediatric case series....
The aim of the study was to investigate changes olfactory and gustatory capacity in patients with multiple sclerosis (MS).20 MS were tested longitudinally for 3 years after initial testing. Threshold Discrimination Identification test (TDI) used subjective olfactometry. Objective olfactometry performed by registering evoked potentials (OEP) EEG. Taste Strip Test (TST) testing.45% showed dysfunction follow-up TDI 50% delayed OEP´s. 20% on visit. mild disease activity 0,3 ± 0,5 relapses over...
To compare outcomes of bilateral cochlear implantation between simultaneous and sequential surgeries.Retrospective study surgical outcome for 54 children who received implants (CIs) over a five-year period.Tertiary health care PATIENTS:: We analyze two CIs period. Thirty-two these simultaneously 22 their sequentially (76 CI operations 108 CI).One hundred eight CIs; Group A-bilateral CI; B- CI.Measurement body temperature; recording drug administration measurement the total length hospital...
We present an interactive and multimodal-based augmented reality system for computer-assisted surgery in the context of ear, nose throat (ENT) treatment. The proposed processing pipeline uses fully digital stereoscopic imaging devices, which support multispectral white light to generate high resolution image data, consists five modules. Input/output data handling, a hybrid multimodal analysis bi-directional (AR) mixed (MR) interface local remote surgical assistance are relevance complete...
We develop a stereo-multispectral endoscopic prototype in which filter-wheel is used for surgical guidance to remove cholesteatoma tissue the middle ear. Cholesteatoma destructive proliferating tissue. The only treatment this disease surgery. Removal very demanding task, even experienced surgeons. It difficult distinguish between bone and cholesteatoma. In addition, it can reoccur if not all particles of are removed, leads undesirable follow-up operations. Therefore, we propose an...
Purpose: Hyperspectral imaging (HSI) is a non-contact optical technique with the potential to serve as an intraoperative computer-aided diagnostic tool. Our work analyzes properties of visible structures in surgical field for automatic tissue categorization. Approach: Building HSI-based analysis system requires accurate ground truth and validation soft these show large variability. We introduce validate two different hyperspectral setups their use properties. First, we present improved...
The optical properties of human tissues are an important parameter in medical diagnostics and therapy. knowledge these parameters can encourage the development automated, computer-driven tissue analysis methods. We determine absorption coefficient μa scattering <inline-formula>μs'</inline-formula> different types obtained during parotidectomy wavelength range 250 to 800 nm. These values determined by high precision integrating sphere measurements combination with optimized inverse Monte...
Although the association between odor concentration and olfactory event-related potential (OERP) has been studied, less is known about influence of airflow on OERP. The aim this study was to investigate rate stimulus OERP in humans. Electroencephalogram data were collected from young healthy volunteers (n = 17) separate sessions where 2-phenylethanol (PEA) delivered following conditions: 8 L/min 50% v/v, 30% 4 100% 60%v/v. Odor concentrations are referred %v/v achieved with air dilution not...
Providing expert opinion in the context of smell disorders is often challenging, not only with regard to general aspects providing an but particularly chemosensory testing. Currently there no consensus which test should be selected and how they executed. This positions paper from Committee on Olfaction Gustation German Society Otorhinolaryngology, Head Neck Surgery aims give concrete recommendations for testing selection execution these test.
Abstract Introduction Improvements of surgical visualization add value to the quality clinical routine and offer opportunity improve education medical staff. The aim this study was determine whether otorhinolaryngology trainees gain additional comprehension anatomical structures site when 3D is used. Methods Data were collected from ENT microsurgical courses middle ear, inner ear lateral skull base at four university departments (Charité (Berlin), Martin Luther University Halle-Wittenberg...
Hyperspectral imaging (HSI) is a non-contact optical technique with the potential to serve as an intraoperative computer-aided diagnostic tool. This work analyzes properties of visible structures in surgical field for automatic tissue categorization. Building HSI-based analysis system requires accurate ground truth and validation soft these show large variability. In this paper, we introduce validate two different hyperspectral setups their use properties. First, present improved...
Abstract Sniffing four different odorants, bi‐daily, for at least 3 months can improve olfactory function. The aim of the current study was to examine whether a relatively short (2 week) exposure period, an immersive large number diverse odorants Twenty‐five patients with various dysfunctions were exposed 72 dispersed into air‐controlled space, while in group. Each odorant singularly from one side room using purpose‐built apparatus. period ran 14 consecutive days, daily sessions...
The last years' developments could show that the rehabilitation with hearing implants is a field highest potential for development and innovation in otorhinolaryngology. New or extended indications were seen of implants, new surgical techniques, respective strategies.With background limited resources, increasing number subjects suffering from disorders, thus CI carriers as well need life-long follow-up are one major challenges future. In order to cope this situation, completely strategies...
Objective: To test the hypothesis that olfactory (OF) and gustatory function (GF) is disturbed in patients with autoimmune encephalitides (AE). Methods: The orthonasal OF was tested 32 AE age- sex-matched healthy controls (HC) standardized Threshold Discrimination Identification (TDI) score. This validated testing method yields individual scores for threshold (T), odor discrimination (D) identification (I), along a composite TDI GF determined by Taste Strip Test (TST). Results: Overall,...
Abstract We present a stereo-multispectral endoscopic prototype using filter-wheel to guide the removal of cholesteatoma tissue in middle ear. An image-based method is used that combines multispectral classification for detection be removed and 3Dreconstruction determine its metric dimensions. The illumination ranges from λ = 400 nm 500 with step-size 20 nm, which results six different narrow-band modes. For classical RGB imaging calculations, broadband mode applied before after...
Nasal septum perforations (NSP) have many uncomfortable symptoms for the patient and a highly negative impact on quality of life. NSPs are closed using patient-specific implants or surgery. Implants created either under anesthesia silicone impressions 3D models from CT data. Disadvantages safety increased risk morbidity radiation exposure.In context otorhinolaryngologic surgery, we present gentle approach to treating NSP with new image-based, contactless, radiation-free measurement method...
Die Vena jugularis interna stellt für den Chirurgen während zahlreicher zervikaler Eingriffe eine bedeutende Landmarke dar. In nächster Nähe der Drosselvene verläuft N. accessorius. Duplikatur ist seltene venöse Malformation, die in wenigen Fällen mit einer Lageanomalie des XI. Hirnnerven assoziiert sein kann. Wir berichten über intraoperativen Zufallsbefund hohen inkompletten und diskutieren Ätiologie Auftreten besonderer Gewichtung auf Lage
Cholesteatoma of the ear can lead to life-threatening complications and its only treatment is surgery. The smallest remnants cholesteatoma recurrence this disease. Therefore, optical properties tissue are high importance identify remove all during therapy. In paper, we determine absorption coefficient µ a scattering s ′ bone samples in wavelength range 250 nm 800 obtained five surgeries. These values determined by precision integrating sphere measurements combination with an optimized...
An osseous choristoma is a benign tumor consisting of regular bone tissue in an irregular localization. Choristomas the head and neck region are rare. Most frequently, they found tongue or oral mucosa. There also very few reports on choristomas submandibular region. We present case woman with large, caudal within lateral cervical triangle. Literature review given about all reported cases neck. The pathogenesis yet unexplained. Our supports theory that development reaction to former trauma....