- Cerebrospinal fluid and hydrocephalus
- Spinal Dysraphism and Malformations
- Traumatic Brain Injury and Neurovascular Disturbances
- Fetal and Pediatric Neurological Disorders
- Neonatal and fetal brain pathology
- Neurosurgical Procedures and Complications
- Central Venous Catheters and Hemodialysis
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Congenital Diaphragmatic Hernia Studies
- Meningioma and schwannoma management
- Congenital Heart Disease Studies
- Neuroblastoma Research and Treatments
- Neonatal Respiratory Health Research
- Eicosanoids and Hypertension Pharmacology
- Cardiac Arrest and Resuscitation
- Takotsubo Cardiomyopathy and Associated Phenomena
- Neuroscience of respiration and sleep
- Spinal Cord Injury Research
- Pharmacological Effects and Toxicity Studies
- Vascular Malformations Diagnosis and Treatment
- Cleft Lip and Palate Research
- Sarcoma Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Spinal Hematomas and Complications
Humboldt-Universität zu Berlin
2018-2024
Charité - Universitätsmedizin Berlin
2013-2024
Freie Universität Berlin
2018-2024
Klinikum Kassel
2017
Medizinische Hochschule Hannover
2017
Dietrich Bonhoeffer Klinikum
2017
After aneurysmal subarachnoid hemorrhage, the use of lumbar drains has been suggested to decrease incidence delayed cerebral ischemia and improve long-term outcome.To determine effectiveness early cerebrospinal fluid drainage added standard care in patients after hemorrhage.The EARLYDRAIN trial was a pragmatic, multicenter, parallel-group, open-label randomized clinical with blinded end point evaluation conducted at 19 centers Germany, Switzerland, Canada. The first patient entered January...
Abstract Introduction Endoscopic skull base approaches are broadly used in modern neurosurgery. The support of neuronavigation can help to effectively target the lesion avoiding complications. In children, endoscopic-assisted surgery combination with navigation systems becomes even more important because morphological variability and rare diseases affecting sellar parasellar regions. This paper aims analyze our first experience on augmented reality endoscopic a pediatric case series....
Freehand ventricular catheter placement may represent limited accuracy for the surgeon's intent to achieve primary optimal position.To investigate of a guide assisted by simple mobile health application (mhealth app) in multicenter, randomized, controlled, blinded study (GAVCA study).In total, 139 eligible patients were enrolled 9 centers. Catheter was evaluated 3 different components: number cannulation attempts, grading scale, and anatomical position tip. The endpoint rate grade I...
Abstract Purpose Neuroendoscopic procedures for treatment of term and preterm newborn infants, such as endoscopic lavage posthemorrhagic hydrocephalus, are gaining popularity despite sparse data. This single-institution report compiles all neuroendoscopic surgical performed in neonates during a 10-year period. Methods Charts electronic records were reviewed consecutive newborns who underwent procedure before reaching postmenstrual age 44 weeks between 09/2010 09/2020. Available documentation...
Precise planning and execution is key for neuroendoscopic interventions which may be based on different available aiding technologies. The aim of this retrospective study to report a case-based utilization guided neuroendoscopy develop stratification algorithm the We reviewed consecutive cases performed at our center from 2016 2018. distinguished between patients receiving new burr hole (group A) with preexisting B). Case specific technical requirements procedure execution, complication...
The standard technique for the placement of ventricular catheters (VC) comprises a high proportion malpositioning catheter (12.5 to 40%). Technical advances such as neuronavigation or ultrasound have been shown increase accuracy procedure. Since these means result in significant technical and time consuming efforts, they are used selected cases only. In order simplify controlled newly developed smartphone assisted guiding tool has introduced. this study efficacy safety is determined. This...
Congenital intracranial cysts account for a significant portion of lesions in the pediatric population. The efficiency surgical treatment cohort with arachnoid (ACs) at different locations regarding clinical symptoms and mass effect was evaluated.
Abstract Background Hydrocephalus may present with heterogeneous signs and symptoms. The indication for its treatment the optimal drainage in complex cases be challenging. Telemetric intracranial pressure measurements (TICPM) open new perspectives those circumstances. We report our experiences using Neurovent-P-tel Sensor Reservoir a retrospective study. Methods A series of 21 patients (age range 10–39.5 years) treated Pediatric Neurosurgical Unit receiving TICPM was analyzed. In 8 patients,...
Abstract Objective The challenge of pediatric brain tumor surgery is given due to a relative low prevalence but high heterogeneity in age, localization, and pathology. Improvements long-term overall survival rates were achieved during the past decades stressing importance multidisciplinary decision process guided by national treatment protocol. We reviewed entire spectrum surgeries from perspective an interdisciplinary neuro-oncology center Germany. Methods Every patient who underwent...
Resection of brain tumors may lead to new-onset seizures but also reduce seizure rates in patients presenting with seizures. Seizures are seen at presentation about 24% tumors. For lesional epilepsy general, early resection is associated improved control. However, the literature limited regarding occurrence postoperative seizures, or control those following resections extratemporal low-grade gliomas (LGGs) children.
Traumatic brain injury (TBI) is one of the leading causes death and disability in children. Medical therapy remains limited, decompressive craniectomy (DC) an established rescue case elevated intracranial pressure (ICP). Much discussion deals with clinical outcome after severe TBI treated DC, while data on pediatric population rare. We report our experience treating two different treatment setups at same academic institution.
Abstract Introduction The TROPHY registry has been established to conduct an international multicenter prospective data collection on the surgical management of neonatal intraventricular hemorrhage (IVH)-related hydrocephalus possibly contribute future guidelines. allows comparing techniques treat hydrocephalus, such as external ventricular drainage (EVD), access device (VAD), subgaleal shunt (VSGS), and neuroendoscopic lavage (NEL). This first status report presents results standard care...
Objective: Evidence for the duration of perioperative antibiotic prophylaxis (PAP) after correction craniosynostosis in children is scarce. We evaluated necessary PAP to ensure a minimal rate postoperative wound infections. Methods: In this monocentric, retrospective, and prospective pilot study, two protocols were compared. From August 2017 May 2018, treatment group 1 (TG 1) was treated using standard protocol with at least three doses antibiotics. Between 2018 March 2019, shortened...
Abstract Objective Cerebrospinal fluid (CSF) diversion shunt systems remain to be the most common treatment for pediatric hydrocephalus. Different valve are used regulate CSF diversion. Preventing complications such as occlusions, ruptures, malpositioning, and over- or underdrainage focus further developments. The proGAV proGAV2.0 system compared in this retrospective study revision-free survival isolated revision paradigms. Methods In first part of study, rates were investigated a...