Tomáš Radovnický

ORCID: 0000-0003-3642-0448
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About
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Research Areas
  • Cerebrospinal fluid and hydrocephalus
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Fetal and Pediatric Neurological Disorders
  • Intracranial Aneurysms: Treatment and Complications
  • Spinal Dysraphism and Malformations
  • Cerebrovascular and Carotid Artery Diseases
  • Advanced Neuroimaging Techniques and Applications
  • Meningioma and schwannoma management
  • Neonatal Respiratory Health Research
  • Pediatric Urology and Nephrology Studies
  • Pleural and Pulmonary Diseases
  • Mathematical Analysis and Transform Methods
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Multiple Sclerosis Research Studies
  • Bone Tumor Diagnosis and Treatments
  • Child Abuse and Related Trauma
  • Management of metastatic bone disease
  • Thermoelastic and Magnetoelastic Phenomena
  • Neurosurgical Procedures and Complications
  • Aortic aneurysm repair treatments
  • Vascular Malformations Diagnosis and Treatment
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Hematological disorders and diagnostics
  • S100 Proteins and Annexins
  • Intraoperative Neuromonitoring and Anesthetic Effects

Jan Evangelista Purkyně University in Ústí nad Labem
2016-2024

Abstract Computational fluid dynamics (CFD) has been studied as a tool for the stratification of aneurysm rupture risk. We performed CFD analysis in patient operated on ruptured anterior communicating artery aneurysm. The point was identified during surgery. and blood vessels were segmented from computed tomography angiography to prepare model simulations. found that streamlines showed concentrated inflow jet directed straight at point, high wall shear stress sac. Thus specific local...

10.1055/s-0037-1604286 article EN Journal of Neurological Surgery Part A Central European Neurosurgery 2017-08-11

Abstract Introduction The TROPHY registry has been established to conduct an international multicenter prospective data collection on the surgical management of neonatal intraventricular hemorrhage (IVH)-related hydrocephalus possibly contribute future guidelines. allows comparing techniques treat hydrocephalus, such as external ventricular drainage (EVD), access device (VAD), subgaleal shunt (VSGS), and neuroendoscopic lavage (NEL). This first status report presents results standard care...

10.1007/s00381-021-05258-w article EN cc-by Child s Nervous System 2021-06-29

The simultaneous cytological and metabolic investigation of various extravascular body fluids (EBFs) provides clinically relevant information about the type intensity immune response in particular organ systems. oxidative burst professional phagocytes with concomitant production reactive oxygen species consumes a large amount is cause switch to development anaerobic metabolism. We assessed relationships between percentages neutrophils, aerobic metabolism, tissue damage via determination...

10.3390/life12020160 article EN cc-by Life 2022-01-21

Brain ischemia after central nervous system (CNS) bleeding significantly influences the final outcome of patients. Catalytic activities aspartate aminotransferase (AST) in cerebrospinal fluid (CSF) to detect brain were determined this study. The principal aim our study was compare dynamics AST 1956 CSF samples collected from 215 patients within a 3-week period CNS hemorrhage. We compared concentrations catalytic two patient groups: survivors (Glasgow Outcome Score (GOS) 5–3) and vegetative...

10.3390/brainsci10100698 article EN cc-by Brain Sciences 2020-10-01

10.48095/cccsnn202418 article Česká a slovenská neurologie a neurochirurgie 2024-02-29

Background Understanding the risk factors leading to intracranial aneurysm (IA) rupture have still not been fully clarified. They are vital for proper medical guidance of patients harboring unruptured IAs. Clarifying hemodynamics associated with point could help provide useful information about some factors. Thus far, few studies studied this issue often diverging conclusions. Methods We identified a in operated an IAs during surgery, using combination preoperative computed tomography (CT)...

10.3389/fneur.2024.1364105 article EN cc-by Frontiers in Neurology 2024-05-20

Abstract Transethmoidal encephalocele is a rare condition in adult patients. It usually diagnosed during childhood by cerebrospinal fluid (CSF) rhinorrhea, meningitis, nasal mass, or seizures. We present case of an woman with CSF rhinorrhea following resection occipital meningioma. The cribriform plate defect containing the was computed tomography and magnetic resonance imaging. Transcranial surgery using patch performed successfully. also discuss possible pathophysiologic mechanisms...

10.1055/s-0038-1676621 article EN Journal of Neurological Surgery Part A Central European Neurosurgery 2018-12-24

Extravasation of blood in the central nervous system (CNS) represents a very strong damaged associated molecular patterns (DAMP) which is followed by rapid inflammation and can participate worse outcome patients. We analyzed cerebrospinal fluid (CSF) from 139 patients after CNS hemorrhage. compared 109 survivors (Glasgow Outcome Score (GOS) 5-3) 30 with poor outcomes (GOS 2-1). Statistical evaluations were performed using Wilcoxon signed-rank test Mann–Whitney U test. Almost same numbers...

10.3390/life11040300 article EN cc-by Life 2021-04-01

Idiopathic normal pressure hydrocephalus (iNPH) is a treatable disease of an elderly people. It`s known for 50 years, but there are still some controversies, especially in the diagnostic algorithm. Disproportionately enlarged subarachnoid space (DESH) seems to be important radiological feature iNPH, it`s not present all patients. The aim our study was analyse appearance DESH set

10.1186/2045-8118-12-s1-p43 article EN cc-by Fluids and Barriers of the CNS 2015-01-01

Masarykova nemocnice v Ústí nad

10.36290/neu.2016.045 article CS Neurologie pro praxi 2016-08-01

Idiopathic normal pressure hydrocephalus (iNPH) is well known as a treatable syndrome affecting an elderly people. There lack of specific radiological features, which can identify the iNPH patient. Diffusion tensor imaging (DTI) MRI technique for evaluation microstructural white matter characteristics, be affected by iNPH. Aim this study was to find DTI sign diagnosis.

10.1186/2045-8118-12-s1-p42 article EN cc-by Fluids and Barriers of the CNS 2015-01-01

The aim of our study was to the association between end-of-surgery facial nerve stimulation threshold and extent tumor resection in case grade IV vestibular schwannomas.Grade VSs represent a surgical challenge as risk/benefit ratio must be considered balancing satisfactory against good postoperative functional outcome. We reviewed cumulative series 57 patients with large/giant who were operated on by retrosigmoid approach period from 2008 2018 two European centers, namely San Filippo Neri...

10.1080/02688697.2023.2244581 article EN British Journal of Neurosurgery 2023-08-17

Introduction: The purpose of the study was to evaluate outcomes craniocervical junction tumor surgery.

10.1055/s-2008-1093249 article EN Skull base 2008-09-01
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