- Immune Cell Function and Interaction
- Viral-associated cancers and disorders
- Lymphoma Diagnosis and Treatment
- Nanoparticles: synthesis and applications
- Cytomegalovirus and herpesvirus research
- Cancer Immunotherapy and Biomarkers
- Bacteriophages and microbial interactions
- Gold and Silver Nanoparticles Synthesis and Applications
- Biosensors and Analytical Detection
- Nanoparticle-Based Drug Delivery
- Advanced biosensing and bioanalysis techniques
Royal College of Surgeons in Ireland - Bahrain
2024
University of Limerick
2020-2024
Institute of Molecular and Translational Medicine
2024
Palacký University Olomouc
2024
University Hospital Olomouc
2024
In classical Hodgkin lymphoma (cHL), responsiveness to immune-checkpoint blockade (ICB) is associated with specific tumor microenvironment (TME) and peripheral blood features. The role of ICB in nodular lymphocyte predominant (NLPHL) not established. To gain insights into its potential NLPHL, we compared TME signatures between HLs using an integrative multiomic analysis. A discovery/validation approach 121 NLPHL 114 cHL patients highlighted >2-fold enrichment programmed cell death-1 (PD-1)...
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