A5108276692- Crystallization and Solubility Studies
- Bladder and Urothelial Cancer Treatments
- X-ray Diffraction in Crystallography
- Urinary and Genital Oncology Studies
- Renal cell carcinoma treatment
- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Renal and related cancers
- Acoustic Wave Phenomena Research
- Urological Disorders and Treatments
- Metastasis and carcinoma case studies
- Cancer Genomics and Diagnostics
- Renal and Vascular Pathologies
- Radiomics and Machine Learning in Medical Imaging
- Urologic and reproductive health conditions
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- AI in cancer detection
- Advanced Antenna and Metasurface Technologies
- Testicular diseases and treatments
- RNA Research and Splicing
- Infectious Disease Case Reports and Treatments
- Cancer Immunotherapy and Biomarkers
- Muscle and Compartmental Disorders
- Antenna Design and Analysis
Nippon Medical School Hospital
2016-2025
Nippon Medical School
2016-2024
RIKEN Center for Advanced Intelligence Project
2024
Hokkaido University
2019-2023
Tsukuba Memorial Hospital
2022-2023
Ehime University
2021
Japanese Foundation For Cancer Research
2018-2020
Tokai University
2019
University of Tsukuba Hospital
2018
This study presents the enfortumab vedotin (EV) treatment analysis at our institution. We retrospectively analyzed patients with metastatic urothelial cancer (mUC) treated EV between January 2021 and October 2023. was administered 1.25 mg/kg on days 1, 8, 15 in a 28-day cycle. Whole-body computed tomography scans were performed to assess response. Patient characteristics, histories, response rates, progression-free survival, adverse events evaluated. Response rates determined, recorded....
690 Background: VI-RADS is widely used to identify muscle-invasive bladder cancer (MIBC). However, it not known whether structural category (SC; based on T2-weighted images) alone useful in diagnosing clinicopathological features and prognosis of cancer. This study investigates the diagnostic performance SC detection MIBC. We also measured tumour contact length (TCL), difference signal intensity ratio (dSIR) coefficient variation (CV) within T2WI. evaluated these factors could improve for...
381 Background: Although there studies have been reported that brachytherapy (BT) for prostate cancer is associated with an increased incidence of metachronous urinary bladder (MBC), few clarified differences in the clinicopathological features (CPF) MBC between BT and prostatectomy (RP). We studied risk CPF RP groups our hospital after long-term follow-up. Methods: Five hundred four patients treated 471 referred 2006 2017 were reviewed. compared including tumor number, location within...
Interstitial brachytherapy for localised prostate cancer may be followed by transient increases in prostate-specific antigen (PSA) that resolve without therapy. Such PSA bounces associated with an improved outcome but often cause alarm the patient and physician, have defied explanation. We developed a mathematical model to capture interactions between tumour, radiation anti-tumour immune response. The was fitted data from large cohort of patients treated exclusively interstitial...
Deep learning algorithms have achieved great success in cancer image classification. However, it is imperative to understand the differences between deep and human approaches. Using an explainable model, we aimed compare learning-focused regions of magnetic resonance (MR) images with cancerous locations identified by radiologists pathologists. First, 307 prostate MR were classified using a well-established neural network without locational information cancers. Subsequently, assessed whether...
Abstract Accurate prostate cancer screening is imperative for reducing the risk of death. Ultrasound imaging, although easy, tends to have low resolution and high inter-observer variability. Here, we show that our integrated machine learning approach enabled detection pathological high-grade by ultrasound procedure. Our study included 772 consecutive patients 2899 images obtained at Nippon Medical School Hospital. We applied analyses using imaging data clinical detect cancer. The area under...
The optimal treatment modality for locally advanced prostate cancer has not been established. Radiotherapy, hormonal therapy, and combination treatments are the main strategies, although feasibility of radical prostatectomy as a first-line therapy needs to be considered. This retrospective analysis pathological results extracted specimens evaluated long-term oncological outcomes high-risk treated surgically. association number risk factors with outcome was specifically analyzed.We identified...
Abstract Background Prolonged laparoscopic nephroureterectomy (LNU) for upper tract urothelial cancer (UTUC) can increase the frequency of intravesical recurrence after surgery. Therefore, it is important urological surgeons to have knowledge on preoperative risk factors prolonged LNU. However, few studies investigated We hypothesized that quantity perirenal fat affects pneumoretroperitoneum time (PRT) retroperitoneal LNU (rLNU). This study aimed investigate PRT during rLNU. Methods reviewed...
Several effective treatment modalities against metastatic castration-resistant prostate cancer (mCRPC) are available; however, an unmet clinical need persists for mCRPC because resistance to these therapies is inevitable. This study aimed evaluate the status of comprehensive genomic profiling (CGP) and its impact on subsequent treatments patients with at our hospital.
High body mass index (BMI) and visceral obesity were reported to be associated with prolonged transperitoneal laparoscopic radical nephrectomy (LRN); however, factors that prolong retroperitoneal LRN remain unknown. We therefore investigated performed by non-expert surgeons.We defined non-experts surgeons as not certified perform surgery the Japanese Society of Endourology. retrospectively reviewed medical records 59 consecutive patients renal cell carcinoma treated at our hospital between...
Robot-assisted laparoscopic prostatectomy (RALP) for prostate cancer was introduced in 2000 and rapidly gained popularity. The Da Vinci Surgical System? can ensure improved local control of fewer perioperative complications. However, RALP is performed the steep-Trendelenburg position (a combination lithotomy head-down tilt position/Lloyd-Davies position) to obtain a good surgical view, as result, well leg compartment syndrome (WLCS) become serious complication RALP. Here, we report case WLCS...
BACKGROUND Aplastic or twiglike middle cerebral artery (Ap/T-MCA) is a rare anomaly characterized by unilateral MCA occlusion with plexiform vessels that causes hemorrhagic and (less commonly) ischemic strokes. The reasons for this are rarely discussed, thus optimal treatment Ap/T-MCA remains controversial. Here, the authors report case of transient attacks treated bypass surgery discuss mechanism development methods. OBSERVATIONS A 62-year-old hypertensive man transient, recurrent left...
Active surveillance (AS) is one of the treatment methods for patients with small renal masses (SRMs; < 4 cm), including cell carcinomas (RCCs). However, some RCCs may exhibit aggressive neoplastic behaviors and metastasize. Little known about imaging biomarkers capable identifying potentially RCCs. Contrast-enhanced computed tomography (CECT) often detects collateral vessels arising from angiogenesis in Therefore, this study aimed to evaluate association between SRM differential diagnoses...
Anatomical variations often occur in the anterior communicating artery (AComA) complex, and a careful preoperative evaluation is required before repair of this lesion. We report case fenestrated AComA complex mimicking an unruptured cerebral aneurysm. A 49-year-old woman was referred to our hospital under suspicion aneurysms left middle on magnetic resonance angiography (MRA). Additional three-dimensional computed tomographic (CTA) showed lesion arising from with maximum diameter 4.2 mm....
Various devices for isolating and detecting circulating tumor cells (CTCs) have been developed, whereas the CellSearch® system has clinically used in numerous prostate CTC studies. CTCs might become more useful surrogate markers of cancer, they should be measured all settings, but a smaller, low-cost capture is required.An inexpensive highly sensitive microfluidic CTC-capture polymeric chip, developed by Toyama Industrial Technology Center, as described following text, was to assess number...
<b><i>Purpose:</i></b> Bladder endometriosis (BE) is rare. Deep invasive difficult to control with medications alone; such cases need surgical treatment. Good results of laparoscopic partial cystectomy a transurethral (TU) resectoscope by the see-through technique for patients BE are reported. <b><i>Materials and Methods:</i></b> From January 2008 February 2016, 12 symptomatic were seen in our institution. The chief complaints 9 micturition...
One of the major concerns patients with upper tract urothelial carcinoma (UTUC) treated nephroureterectomy is intravesical recurrence (IVR). The purpose present study was to investigate predictive risk factors for IVR after retroperitoneoscopic (RNU) UTUC.Clinicopathological and surgical information were collected from medical records 73 RNU non-metastatic UTUC, without a history or concomitant bladder cancer. association between clinicopathological surgery-related factors, including...
We have found that the electrical properties of an organic charge transfer salt are qualitatively affected by slight differences in conformation one ethylene groups, which is not involved conduction pathways.
The case presented is of a 47-year-old patient with an extravesical pedunculated bladder leiomyoma, which was difficult to distinguish from retroperitoneal tumor. Preoperatively, it suspected be tumor and laparotomy resection performed. lntraoperatively, the were connected by cord-like tissue. A retrospective review preoperative images revealed that tissue, identified intraoperatively, also present. Bladder leiomyomas can grow as tumors. Therefore, when continuity between only object,...
Postoperative rhabdomyolysis is a rare but potentially fatal surgical complication. We experienced case of after laparoscopic radical nephrectomy (LRN). Right renal carcinoma was diagnosed in 31-year-old woman with body mass index 28.5 kg/m2. She underwent right retroperitoneal LRN the lateral decubitus position. The operating time approximately 5 hours. Immediately surgery, she reported pain left buttock, and reddish discoloration urine observed. On basis these symptoms, an elevated serum...
Abstract Background The Vesical Imaging Reporting and Data System (VI-RADS) is widely used for predicting muscle-invasive bladder cancer (MIBC). This study aimed to determine the clinicopathological significance of VI-RADS ≧4 (VI≧4) group. Methods Patients who underwent transurethral resections tumors during period preoperative magnetic resonance imaging were considered. patients pathologically diagnosed with urothelial carcinoma (UC). We first compared results scores 3 4 cut-off score MIBC;...