A5082334643- Spaceflight effects on biology
- EEG and Brain-Computer Interfaces
- Cardiovascular and exercise physiology
- Heart Rate Variability and Autonomic Control
- Functional Brain Connectivity Studies
- Physics and Engineering Research Articles
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Space Exploration and Technology
- Neural and Behavioral Psychology Studies
- Muscle activation and electromyography studies
- HIV/AIDS Research and Interventions
- Neural dynamics and brain function
- Species Distribution and Climate Change
- Optical Imaging and Spectroscopy Techniques
- Motor Control and Adaptation
- Dementia and Cognitive Impairment Research
- Paranormal Experiences and Beliefs
- Sports Performance and Training
- Cardiovascular and Diving-Related Complications
- Inorganic Fluorides and Related Compounds
- Stroke Rehabilitation and Recovery
- Stress Responses and Cortisol
- Digital Innovation in Industries
- High Altitude and Hypoxia
German Sport University Cologne
2016-2025
University of Southern California
2024-2025
Deutsche Bahn (Germany)
2024
GeoSphere Austria
2023-2024
University of the Sunshine Coast
2014-2023
Southern California Institute for Research and Education
2016-2023
Memorial University of Newfoundland
2019-2023
Mammazentrum Hamburg
2022
Central Institution for Meteorology and Geodynamics
2021-2022
Berlin Heart (Germany)
2021
To investigate the immune response and mechanisms associated with severe coronavirus disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal bronchial samples from 19 clinically well-characterized patients moderate or critical five healthy controls. We identified airway epithelial cell types states vulnerable to acute respiratory syndrome 2 (SARS-CoV-2) infection. In COVID-19, cells showed an average three-fold increase in expression of SARS-CoV-2 entry receptor...
Background. Human immunodeficiency virus (HIV)–infected individuals are at increased risk of herpes zoster (HZ), even in the antiretroviral therapy (ART) era. Because concerns exist about use live-attenuated vaccines immunocompromised individuals, a subunit vaccine may be an appropriate alternative.
The AF-6/afadin protein, which contains a single PDZ domain, forms peripheral component of cell membranes at specialized sites cell-cell junctions. To identify potential receptor-binding targets AF-6 we screened the domain against range COOH-terminal peptides selected from receptors having domain-binding termini. interacts with subset members Eph subfamily RTKs via its COOH terminus both in vitro and vivo. Cotransfection green fluorescent protein-tagged fusion protein full-length into...
Efficient transduction tools are a hallmark for both research and therapy development. Here, we introduce new insights into the generation of lentiviral vectors with improved performance by utilizing producer cells increased production rates extracellular vesicles through CD9 overexpression. Most human secrete small from their surface (microvesicles) or intraluminal endosome-derived membranes (exosomes). In particular, enhanced levels tetraspanin result in significantly numbers exosome-like...
Previous research suggests that different exercise modes and intensities lead to variations in brain cortical activity. However, because of variability limitations previous study designs, the mechanisms behind this link remain unclear. The aim was evaluate effects on activity are dependent mode, intensity, individual preferences localize these changes within frontal, temporal, parietal, occipital cortexes brain.Twelve runners were asked perform four (treadmill, bicycle, arm crank, isokinetic...
Exercise interventions to prevent dementia and delay cognitive decline have gained considerable attention in recent years. Human animal studies demonstrated that regular physical activity targets brain function by increasing reserve. There is also evidence of structural changes caused exercise preventing or delaying the genesis neurodegeneration. Although initial indicate enhanced performance patients with mild impairment (MCI) following an intervention, little known about effect extensive,...
Aims Exposure to artificial gravity (AG) at different G loads and durations on human centrifuges has been shown improve orthostatic tolerance in men. However, the effects women of an individual-specific AG training protocol are not known. Methods We examined 90 minutes vs. supine rest limit (OTL), using head up tilt lower body negative pressure until presyncope 7 men 5 women. Subjects were placed centrifuge nacelle while instrumented after one-hour they underwent either: 1) exposure (90...
Recent studies have highlighted the importance of regular exercise on cognitive function in aging populations, with aerobic and cardiovascular fitness having received largest amount research attention. However, relationship between mode underlying behavioral modification neural activation remains unknown. The present study, therefore, sought to examine associations different modes working memory (WM) aspect executive as well its task-evoked brain late middle-aged population. Seventy adults...
<title>Abstract</title> It is essential that astronauts maintain optimal cognitive function in order to successfully complete critical tasks demanding environments. However, stress can impair executive functions and decision-making, which may ultimately affect mission success. Training establishing routines help ensure efficiency free up resources handle unforeseen challenges effectively. To evaluate workload management a dual-task the study investigated behavioural data (Reaction Time Error...