- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
- MRI in cancer diagnosis
- Cerebrovascular and Carotid Artery Diseases
- Advanced X-ray and CT Imaging
- Cardiovascular Effects of Exercise
- Congenital Heart Disease Studies
- Atomic and Subatomic Physics Research
- Central Venous Catheters and Hemodialysis
- Coronary Interventions and Diagnostics
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Advanced Neuroimaging Techniques and Applications
- Meningioma and schwannoma management
- Coronary Artery Anomalies
- Ultrasound and Hyperthermia Applications
- Renal and Vascular Pathologies
- Medical Imaging Techniques and Applications
- Moyamoya disease diagnosis and treatment
- Lanthanide and Transition Metal Complexes
- Vascular anomalies and interventions
- Glioma Diagnosis and Treatment
- Vascular Malformations and Hemangiomas
- Kawasaki Disease and Coronary Complications
- Cardiomyopathy and Myosin Studies
Heidelberg University
2025
University Hospital Heidelberg
2025
Central Institute of Mental Health
2025
University of Tübingen
2008-2019
Society of Interventional Radiology
2019
Praxis für Humangenetik Tübingen
2017-2019
Universitätsklinikum Tübingen
2007-2012
University of California, Los Angeles
2008
Aarhus University Hospital
2007
Current magnetic resonance imaging (MRI) technology allows the determination of patient-individual coronary tree structure, detection infarctions, and assessment myocardial perfusion. Joint inspection these three aspects yields valuable information for therapy planning, e.g., through classification myocardium into healthy tissue, regions showing a reversible hypoperfusion, infarction with additional on corresponding supplying artery. Standard protocols normally provide image data different...
Tobacco use disorder (TUD) remains a global health crisis characterized by high relapse rates despite extensive cessation efforts. This study aims to enhance treatment outcomes addressing the cognitive and neural imbalances associated with habitual goal-directed behaviours among individuals TUD. We hypothesise that integrating high-intensity interval training (HIIT), remediation (CRT) via app-based chess standard smoking program (SCP) for control sleep quality will be improved, thereby...
Patients with Moyamoya Disease (MMD) need hemodynamic evaluation of vascular territories at risk stroke. Today's investigative standards include H215O PET/CT pharmacological challenges acetazolamide (ACZ). Recent developments suggest that CO2-triggered blood‑oxygen-level-dependent (BOLD) functional MRI might provide comparable results to current standard methods for territorial hemodynamics, while being a more widely available and easily implementable method. This study examines newly...
The objective of our study was to assess the feasibility and diagnostic performance time-resolved MR angiography (MRA) in pretreatment evaluation peripheral vascular malformations at 1.5 T.Twenty-two consecutive patients (15 women seven men; mean age, 22.1 ± 12.1 years) who were known or suspected have studied using MRA with interleaved stochastic trajectories parallel acquisition followed by conventional (n = 12). All studies performed on a 1.5-T whole-body system. Image sets independently...
<h3>Background</h3> Restrictive right ventricular (RV) physiology is a phenomenon considered potentially beneficial when detected in children and adolescents with repaired tetralogy of Fallot (ToF). It typically characterised by antegrade flow the pulmonary artery late diastole at time atrial contraction. However, little known about impact restrictive on intrinsic diastolic RV function or lusitropy. <h3>Methods</h3> Diastolic was prospectively assessed baseline level during dobutamine...
The race for creating an automated patch clamp has begun. Here, we present a novel technology to produce true gigaseals and whole cell preparations at high rate. Suspended cells are flushed toward the tip of glass micropipettes. Seal, whole-cell break-in, pipette/liquid handling fully automated. Extremely stable seals access resistance guarantee recording quality. Data obtained from different types sealed inside pipettes show long-term stability, voltage seal quality, as well block by...
To compare left ventricular (LV) volume and mass assessment using two-dimensional (2D) cine steady-state free precession (SSFP) k-t space broad-use linear acquisition speed-up technique (k-t BLAST) accelerated 3D magnetic resonance imaging (MRI).On a commercially available 1.5T MR scanner, 2D SSFP, six- eight-fold BLAST were performed to evaluate LV volumes in 17 volunteers. After semiautomatic segmentation of the different data sets, resulting compared according mean difference, 95%...
The study was approved by the local ethics committee, and informed consent provided all participants prior to examination. aim of assess feasibility whole-body three-dimensional (3D) contrast material-enhanced magnetic resonance (MR) angiography with parallel imaging in phase- section-encoding directions (ie, integrated acquisition technique [iPAT(2); Siemens, Erlangen, Germany]) for anatomic stations combination a single injection material. Whole-body contrast-enhanced MR performed 23...
The purpose of this study was to prospectively evaluate the diagnostic performance contrast material-enhanced magnetic resonance (MR) angiography performed at 3 T for assessment renal artery stenosis (RAS) by using parallel acquisition techniques with high acceleration factors and digital subtraction (DSA) as reference standard. institutional review board approved, written informed consent obtained from all patients. Twenty-nine patients (18 men, 11 women; mean age, 57.1 years +/- 14.3...
Ziel: Detailliertes Wissen über die Anatomie des mesenterialvenösen Systems ist relevant für Eingriffe in der Gastrointestinalchirugie – insbesondere Planung und Durchführung von Transplantationen sowie das Verständnis perioperativen Komplikationen, den Krankheitsverlauf Patienten beeinflussen können. Literaturangaben mesenterialvenöse unterscheiden sich erheblich. Ziel dieser Studie war Klassifizierung mesenterialvenöser Varianten deren Häufigkeitsbestimmung. Material Methoden: Wir...
Objective The objective of this article is to evaluate advanced techniques diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) measurements the optic nerve in patients with neuritis. Methods In prospective institutional review board-approved trial, we examined 15 acute visual loss clinical signs neuritis including thin-slice multi-shot segmented readout long variable echo trains (rs-EPI, RESOLVE) DWI reduced field-of view using a parallel transmit system (rFOV-EPI)....
The race for creating an automated patch clamp has begun. Here, we present a novel technology to produce true gigaseals and whole cell preparations at high rate. Suspended cells are flushed toward the tip of glass micropipettes. Seal, whole-cell break-in, pipette/liquid handling fully automated. Extremely stable seals access resistance guarantee recording quality. Data obtained from different types sealed inside pipettes show long-term stability, voltage seal quality, as well block by...
Purpose: The purpose of this prospective study was to determine the feasibility and accuracy high-spatial-resolution MR imaging at 3 Tesla (T) in preoperative evaluation potential living related kidney donors. Materials Methods: Eighteen donors (8 men, 10 women; mean age, 50.1 ± 14.2 years) for renal transplantation were evaluated with T imaging. A 3-dimensional (3D) gradient-echo angiography (repetition time/echo time, 3.0/1.14 ms; flip, 19–23°; matrix, 512; slice thickness, 1.0 mm) using...
Previous experiences of whole body MR angiography are predominantly available in linear 0.5 M gadolinium-containing contrast agents. The aim this study was to compare image quality on a four-point scale (range 1–4) and diagnostic accuracy 1.0 macrocyclic agent (gadobutrol, n = 80 patients) with (gadopentetate dimeglumine, 85 1.5 T system. Digital subtraction served as standard reference. All examinations yielded quality. There no significant difference (3.76 ± 0.3 versus 3.78 0.3, p n.s.)...
Cardiac MRI is known to be diagnostically valuable in cardiac amyloidosis. Several features are frequently found, including myocardial hypertrophy, diastolic dysfunction, a faster gadolinium blood wash out, pleural and pericardial effusions, diffuse delayed enhancement. MR facilitates the detection of amyloidosis allows longitudinal assessment function. This pictorial review focuses on cases with histologically proven systemic involvement order illustrate typical findings.