Demetri J. Merianos

ORCID: 0000-0002-4604-2535
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About
Contact & Profiles
Research Areas
  • Reproductive System and Pregnancy
  • Hematopoietic Stem Cell Transplantation
  • T-cell and B-cell Immunology
  • Hernia repair and management
  • Organ and Tissue Transplantation Research
  • Appendicitis Diagnosis and Management
  • Neonatal Respiratory Health Research
  • Intestinal Malrotation and Obstruction Disorders
  • Intestinal and Peritoneal Adhesions
  • Tissue Engineering and Regenerative Medicine
  • Muscle Physiology and Disorders
  • Immune Cell Function and Interaction
  • Virus-based gene therapy research
  • Lymphatic System and Diseases
  • Gallbladder and Bile Duct Disorders
  • Pediatric Pain Management Techniques
  • Pelvic and Acetabular Injuries
  • Sports injuries and prevention
  • Congenital gastrointestinal and neural anomalies
  • Planarian Biology and Electrostimulation
  • Pancreatic function and diabetes
  • Mobile Health and mHealth Applications
  • Mobile Learning in Education
  • Teratomas and Epidermoid Cysts
  • Education, Achievement, and Giftedness

Cornell University
2017-2023

Penn Presbyterian Medical Center
2020

NewYork–Presbyterian Brooklyn Methodist Hospital
2019

Weill Cornell Medicine
2017

Children's Hospital of Philadelphia
2008-2014

Children's Center
2008-2014

Children's Hospital of Los Angeles
2013-2014

Hospital of the University of Pennsylvania
2012

University of Pennsylvania
2010

Philadelphia University
2010

The lack of fetal immune responses to foreign antigens, i.e., immunologic tolerance, is the most compelling rationale for prenatal stem cell and gene therapy. However, frequency engraftment following in utero hematopoietic transplantation (IUHCT) murine model reduced allogeneic, compared with congenic, recipients. This observation supports existence an barrier challenges classic assumptions tolerance. Here, we present evidence that presence adaptive response recipients IUHCT failed maintain...

10.1172/jci38979 article EN Journal of Clinical Investigation 2009-08-03

Smartphones are one of the fastest-growing sectors in technology industry, and they continue to evolve combine faster processors, better memory, more efficient operating systems into a compact handheld device. also offer dynamic tool for use personal professional environments.1 The role smartphones medicine continues expand as additional uses applications emerge. An estimated 80% physicians, trainees, medical students smartphones, this percentage is expected increase.2–4 provide multifaceted...

10.4300/jgme-d-13-00238.1 article EN Journal of Graduate Medical Education 2014-06-01

Efficient gene transfer to muscle stem cells (satellite cells) has not been achieved despite broad transduction of skeletal by systemically administered adeno-associated virus serotype 2/9 (AAV-9) in mice. We hypothesized that cellular migration during fetal development would make satellite accessible for following utero intravascular injection. injected AAV-9 encoding green fluorescent protein (GFP) marker into the vascular space mice ranging ages from post-coital day 12 (E12) postnatal 1...

10.1038/mtm.2014.40 article EN cc-by-nc-sa Molecular Therapy — Methods & Clinical Development 2014-01-01

There is currently no gold standard for the type of analgesia or preferred circumcision technique in infants requiring after 1 month age. Our study presents a modified Plastibell technique, which offers excellent surgical outcomes, and can be performed under local anesthesia until 6 months age, thereby avoiding risks general delayed circumcision.This retrospective case series 508 consecutive male between from one institution, who all underwent anesthesia, by same pediatric surgeon, 2013 to...

10.1007/s00383-019-04452-x article EN cc-by Pediatric Surgery International 2019-02-13

Accessory hepatic lobe (AHL) is a rare anatomical variant of the liver that often asymptomatic and discovered incidentally through radiographic imaging. When pedunculated, AHL can undergo ischemic torsion, presenting as severe abdominal pain. Laparoscopic surgery provides an excellent approach to establish definitive diagnose excise offending lobe. In our case, 12-year-old boy presented with Abdominal ultrasound computer tomography demonstrated mass adjacent surrounding inflammation. The...

10.1016/j.epsc.2013.06.006 article EN cc-by-nc-nd Journal of Pediatric Surgery Case Reports 2013-07-20
Dave R. Lal Samir K. Gadepalli Cynthia D. Downard Daniel J. Ostlie Peter C. Minneci and 95 more Ruth M. Swedler Thomas Chelius Laura D. Cassidy Cooper T. Rapp Deborah F. Billmire Steven W. Bruch Rebecca Burns Katherine J. Deans Mary E. Fallat Jason D. Fraser Julia Grabowski Ferdynand Hebel Michael A. Helmrath Ronald B. Hirschl Rashmi Kabre Jonathan E. Kohler Matthew P. Landman Charles M. Leys Grace Z. Mak Jessica Raque Beth Rymeski Jacqueline M. Saito Shawn St Daniel Peter Brad Von Allmen Thomas T. Warner Sana Rokhsefat Deanna E. Morra Martin Offringa Lisa Askie Lauren E. Kelly Naji Kulaylat Dorothy V. Rocourt Anthony Tsai Kathryn Martin Brett W. Engbrecht Mary C. Santos Robert E. Cilley Christopher S. Hollenbeak Peter W. Dillon Masahiro Zenitani Takashi Sasaki Natsumi Tanaka Takaharu Oue Kristine S. Corkum Catherine J. Hunter Timothy B. Lautz Kevin Johnson Marcus D. Jarboe George B. Mychaliska Ryan P. Barbaro Peter Rycus Luciano Ferraz Schopf José Carlos Soares de Fraga Rodrigo Hennemann Porto Luís Santos Douglas José Marques Paulo R Sanchez F Meyer Jane Maria Ulbrich Lindsey B. Armstrong David P. Mooney Shengcai Wang Yuzhu He Yamei Zhang Jie Zhang Rahul Shah Guoshuang Feng Xiaodan Li Wentong Ge Yuanhu Liu Yongli Guo Haihong Liu Jun Tai Xin Infl Alice Miranda Susana Roque Cláudia Serre-Miranda José Miguel Pêgo Jorge Correia‐Pinto Lori A. Zimmerman Jill M. Zalieckas Robert C. Shamberger Athos Bousvaros Walter A. Koltun Tolulope Falaiye Saurabh Saluja Tian-Yi Sun Jialin Mao Shaun A. Steigman Philmo Oh Heather Yeo Art Sedrakyan Demetri J. Merianos Federica Pederiva

10.1016/s0022-3468(18)30356-7 article EN Journal of Pediatric Surgery 2018-06-27
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