A5055526426- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Malaria Research and Control
- Cardiovascular and exercise physiology
- Mosquito-borne diseases and control
- Heart Rate Variability and Autonomic Control
- Vector-borne infectious diseases
- Acute Myocardial Infarction Research
- Cardiovascular Effects of Exercise
- Viral Infections and Vectors
- Pulmonary Hypertension Research and Treatments
- Shoulder Injury and Treatment
- Blood Pressure and Hypertension Studies
- Potassium and Related Disorders
- Nutrition and Health in Aging
- Invertebrate Immune Response Mechanisms
- Ion channel regulation and function
- Magnesium in Health and Disease
- Bartonella species infections research
- Insect and Pesticide Research
- Hemodynamic Monitoring and Therapy
Swedish Medical Center
2024
United States Naval Medical Research Unit SOUTH
2019-2023
Southern Connecticut State University
2023
University of Maryland, Baltimore
1997-2021
London Studio Centre
2019-2020
Kansas State University
2019-2020
Universidad de Antioquia
2019-2020
Western Reserve Hospital
2017-2019
Summa Health System
2019
Ohio University
2019
Nesiritide (synthetic human brain natriuretic peptide) is approved for the treatment of symptomatic heart failure. However, studies peptide in patients with failure have come to conflicting conclusions about effects on glomerular filtration rate (GFR), effective renal plasma flow, natriuresis, and diuresis.To identify a population at high risk dysfunction conventional treatment, we selected creatinine level increased from baseline (within 6 months). We examined nesiritide GFR (measured by...
We examined the hypothesis that weight loss in heart failure patients is associated with elevated daily energy expenditure. Twelve cachectic [age = 73 +/- 6 yr; 15 kg; body mass index (BMI) 21 5 kg/m2], 13 noncachectic (age 67 BMI 27 kg/m2), and 50 healthy elderly controls 69 26 4 kg/m2) were studied. Daily expenditure it components measured using doubly labeled water indirect calorimetry composition by dual-energy X-ray absorptiometry. Fat fat-free lower (P < 0.05) compared controls. was...
To evaluate the extent to which Frank-Starling mechanism is utilized during successive stages of vigorous upright exercise, absolute left ventricular end-diastolic volume and ejection fraction were determined by gated blood pool scintigraphy at rest multilevel maximal bicycle exercise in 30 normal males aged 26-50 yr, who able 125 W or greater. Left end-systolic volume, stroke cardiac output calculated each 3-min stage [25, 50, 75, 100, 125–225 (peak)]. During early (25 W), volumes increased...
It has been shown that the antiarrhythmic and toxic effects of lidocaine may be in part dependent on its two active metabolites, monoethylglycylxylidide (MEGX) glycylxylidide (GX), Presently available gas liquid chromatographic analytic methods require long tedious steps or sophisticated equipment such as chromatography‐mass spectrometry. The assay method reported here with use high‐performance chromotography is rapid allows accurate, precise determination lidocaine, MEGX, GX biologic...
Background — β-Blockade improves survival when administered over a long period of time to patients with heart failure. However, the course any possible deterioration during titration phase has not been reported. Methods and Results We looked at evidence clinical in Metoprolol CR/XL Randomized Intervention Trial Congestive Heart Failure (MERIT-HF) by analyzing events symptoms first 90 days. During titration, Kaplan-Meier curves for combined end point all-cause mortality/all-cause...
Two hundred consecutive catheterized patients with unstable angina pectoris were reviewed to find clinical and noninvasive indicators of left main coronary artery disease (≥ 50% lesion). Thirty-five (17.5% total) had disease. There no differences between without in age, sex, results resting electrocardiogram, congestive heart failure, dyspnea during pain, duration longest arrhythmias, response medical therapy, or other risk factors. Crescendo (worsening pre-existing angina), transient...
The house fly, Musca domestica L. (Diptera: Muscidae), is a disease vector of mechanically transmitted pathogens including bacteria, viruses, and protozoans. Opportunities for pathogen transmission can increase as fly longevity increases. Dietary preferences play an important role in insect longevity; therefore, we investigated preferences, sucrose availability, caloric constraints on longevity. Experimental goals were: 1) to test the effects calorie restriction survival flies by...
Abstract This study describes the evolution of knockdown resistance (kdr) haplotypes in Aedes aegypti response to pyrethroid insecticide use over course 18 years Iquitos, Peru. Based on duration and intensiveness sampling (~10,000 samples), this is most thorough kdr population genetics Ae . date within a city. We provide evidence for direct connection between programmatic citywide spraying increase frequency specific by identifying two evolutionary events population. The relatively high...
This prospective evaluation of 55 consecutive patients, aged 60 years or older, admitted in 1977-1978 to a community hospital coronary care unit for treatment cardiogenic pulmonary edema, examines morality during hospitalization and the subsequent one-year follow-up. Their was based on clinical criteria, without "advantage" Swan-Ganz catheters before widespread use vasodilators severe congestive heart failure. Multiple laboratory features were reviewed determine possible prognostic clues....