A5084408279- Congenital heart defects research
- Cardiac and Coronary Surgery Techniques
- Blood transfusion and management
- Congenital Heart Disease Studies
- Tissue Engineering and Regenerative Medicine
- MicroRNA in disease regulation
- Coronary Artery Anomalies
- Venous Thromboembolism Diagnosis and Management
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Ischemia and Reperfusion
- Anesthesia and Neurotoxicity Research
- Traffic control and management
- Traffic Prediction and Management Techniques
- Mesenchymal stem cell research
- Lipid metabolism and disorders
- Pluripotent Stem Cells Research
- Thermal Analysis in Power Transmission
- Vascular anomalies and interventions
- Evacuation and Crowd Dynamics
- Kawasaki Disease and Coronary Complications
- Cardiac Valve Diseases and Treatments
- Cancer, Stress, Anesthesia, and Immune Response
- Fire Detection and Safety Systems
- Power Quality and Harmonics
- Lightning and Electromagnetic Phenomena
Chinese Academy of Medical Sciences & Peking Union Medical College
2011-2023
Peking Union Medical College Hospital
2014-2023
CCCC Highway Consultants (China)
2021
First Affiliated Hospital of Harbin Medical University
2016
Harbin Medical University
2016
Academy of Medical Sciences
2015
Fu Wai Hospital
2011-2014
Zero to Three
2011
Xiangya Hospital Central South University
2007
Central South University
2007
Vein graft occlusion is deemed a major challenge in coronary artery bypass grafting. Previous studies implied that the no-touch technique for vein harvesting could reduce rate compared with conventional approach; however, evidence on clinical benefit and generalizability of scare.From April 2017 to June 2019, we randomly assigned 2655 patients undergoing grafting at 7 hospitals 1:1 ratio receive or approach harvesting. The primary outcome was computed tomography angiography 3 months...
Abstract Tradition considers that mammalian heart consists of about 70% non‐myocytes (interstitial cells) and 30% cardiomyocytes ( CM s). Anyway, the presence telocytes TC s) has been overlooked, since they were described in 2010 (visit www.telocytes.com ). Also, number cardiac stem cells CSC not accurately estimated humans during ageing. We used electron microscopy to identify estimate human atrial myocardium (appendages). Three age‐related groups studied: newborns (17 days–1 year),...
MicroRNAs (miRNAs) are short, single-stranded and non-coding RNAs, freely circulating in human plasma correlating with vary pathologies. In this study, we monitored early myocardial injury recovery after heart transplantation by detecting levels of muscle-specific miR-133a, miR-133b miR-208a.7 consecutive patients underwent Fuwai hospital 14 healthy controls were included our study. Peripheral vein blood was drawn from on the day just (day 0), 1st, 2nd, 3rd, 7th 14th respectively. Serum...
Sex differences present in the blood management of patients after coronary artery bypass grafts (CABG) surgeries. Tranexamic acid (TXA) performed well maintaining hemostasis during and However, impact sex on control CABG who received TXA was not investigated.Overall, 29,536 undergoing with administration from 2009 to 2019 our hospital were included. Propensity score matching performed. Finally, 6808 males females matched based 23 covariates.Female had a 0.36-fold lower incidence reoperations...
Reoperation for congenital heart disease may be associated with cardiac or vascular injuries during repeat sternotomy, resulting in increased mortality and/or morbidity rates. The aim of this study was to determine the frequency these and outcome. Between January 2012 December 2013, 4256 sternotomy procedures were performed at Pediatric Cardiac Center Fuwai Hospital, including 195 (RS). We retrospectively studied clinical data RS patients 250 randomly selected primary (PS) patients....
The safety and blood management effects of Tranexamic acid (TXA) its dose in coronary artery bypass graft (CABG) were still ambiguous. This study aimed to analyze these TXA effects.Overall, 42,010 patients undergoing CABG enrolled this retrospective cohort study. Patients assigned the group (n = 29,536) no-TXA 12,474). Furthermore, was divided into high-dose (≥50 mg/kg) (16,488) low-dose (<50 (13,048) subgroup. Propensity score matching performed both groups respectively. primary endpoint...
Tranexamic acid (TXA) administered during off-pump coronary artery bypass (OPCAB) surgeries has achieved good blood control in small cohorts. We aimed to investigate the safety issues and hemostasis associated with TXA administration OPCAB a large retrospective cohort study. This study included 19,687 patients from 2009 2019. A total of 1,307 were excluded because they younger than 18 years or certain values missing. Among remaining 18,380 patients, 10,969 group 7,411 no-TXA group. There...
Abstract The purpose of this study was to investigate the fate transplanted cells in central zone myocardial infarction (MI), and clarify relationship between injection‐site impact efficacy cell therapy. MI created by coronary ligation female rats. Three weeks later, 3‐million labelled male bone marrow mesenchymal stem (BMSCs) were directly injected into border (BZC group) or (CZC area. As a control, culture medium same sites. Cell survival evaluated quantitative real‐time polymerase chain...
Transcriptional factors and signaling in the second heart field (SHF) contribute to cardiac development. However, associations of intronic gene variants SHF with congenital disease (CHD) remain ununderstood. Ten single nucleotide polymorphisms (SNPs) from our previous sequencing data were selected then genotyped 383 CHD patients 384 healthy controls a Chinese population. Genotype analyses revealed that minor alleles TBX1: rs12165908 C > G [odds ratio (OR) = 2.64; 95% confidence interval (CI)...
Abstract Background We validated the performance of seven different reagents peroxidase method for sdLDL‐C in two automatic analyzers that are common Chinese laboratories. Methods Seven commercially available assays were analyzed with Beckman AU5400 and Mindray BS2000 analyzers. A total 336 blood samples collected reference interval was also 298 apparently healthy individuals. Serum used comparison precision, recovery, lower limit detection, concurrence analysis, as well reagent. Results The...
Background More elderly patients undergo coronary artery bypass surgery (CABG) than younger patients. Whether tranexamic acid (TA) is still effective and safe in undergoing CABG surgeries unclear. Methods In this study, a cohort of 7,224 ≥70 years were included. Patients categorized into the no TA group, high-dose low-dose group according whether was administered dose administered. The primary endpoint blood loss transfusion after CABG. secondary endpoints thromboembolic events in-hospital...
In the electromechanical design of highway tunnels, calculation voltage drop during fan start-up is an important part electrical design, which related to safe operation whole system, green and energy-saving. The involves setting substations, ultimately affects tunnel engineering scheme. this study, a theoretical analysis, by calculating when axial-flow starts was implemented. method used calculate verify Milashan section 318 National Highway from Linzhi Lhasa. can provide reference for peer...
Multiple second heart field (SHF) transcription factors are involved in cardiac development. In this article we evaluate the relationship between SHF factor polymorphisms and congenital disease (CHD). Ten were used for genotyping, three of these luciferase assay. The risk CHD was increased 4.31 times 1.54 C allele GATA5: rs6061243 G>C G TBX20: rs336283 A>G, respectively. minor alleles SMYD1: rs1542088 T>G, MEF2C: rs80043958 A>G rs6587239 T>C simple types CHD. rs41305803 G>A rs304154...
In order to grasp the driving behavior characteristics of traffic volume ten Lane expressway, this paper will use high-level surveillance video Shenzhen Shuiguan expressway as data source, extract basic flow such volume, running speed, headway and lane change times different models general sections weaving sections, based on road environment information geometric conditions composition cellular automata considering vehicle types are established deeply explore car following driving.
Objective To explore the application effects of Orem self-care nursing mode on improving complications and quality life in patients with Alzheimer. Methods The study investigated 184 Alzheimer who were hospitalized from July 2013 to 2015. The participants divided into control group (n=92) intervention using random number table. received routine care while mode. incidence complications, IQ level, activity daily living compared between two groups. Results The performed...