A5101687495- Sepsis Diagnosis and Treatment
- Immune Response and Inflammation
- Traumatic Brain Injury and Neurovascular Disturbances
- Hemodynamic Monitoring and Therapy
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Nosocomial Infections in ICU
- Immune cells in cancer
- Natural product bioactivities and synthesis
- Pancreatitis Pathology and Treatment
- Cancer, Hypoxia, and Metabolism
- Antifungal resistance and susceptibility
- Sinusitis and nasal conditions
- Transplantation: Methods and Outcomes
- Fungal Infections and Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Safety and Risk Management
- Antimicrobial Peptides and Activities
- Traditional Chinese Medicine Studies
- Hematological disorders and diagnostics
- Antibiotic Use and Resistance
- Acute Kidney Injury Research
- Diabetic Foot Ulcer Assessment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Immune Cell Function and Interaction
The First Affiliated Hospital, Sun Yat-sen University
2006-2023
Sun Yat-sen University
2006-2023
Xian Yang Central Hospital
2013
Wuxi People's Hospital
2013
Ischemia-reperfusion injury (IRI) has thus far been considered as an inevitable component of organ transplantation, compromising outcomes, and limiting availability. Ischemia-free transplantation is a novel approach designed to avoid IRI, with the potential improve outcomes.
Abstract Ischemia–reperfusion injury (IRI) remains the major reason for impaired donor graft function and increased mortality post-liver transplantation. The mechanism of IRI involves multiple pathophysiological processes numerous types cells. However, a systematic comprehensive single-cell transcriptional profile intrahepatic cells during liver transplantation is still unclear. We performed transcriptome analysis 14,313 from tissues collected pre-procurement, at end preservation 2 h...
Hemodynamic instability plays a major role in the pathogenesis of systemic inflammation, tissue hypoxia, and multiple organ dysfunction syndrome associated with severe acute pancreatitis (SAP). Aggressive fluid replacement is one key interventions for hemodynamic support pancreatitis.1 Although need resuscitation well established, goals components this treatment are still matter debate. We used strategies according to early goaldirected therapy (EGDT); we measured effects these volume on...
Background Many studies have shown that continuous renal replacement therapy (CRRT) could clean lactate and treat the hyper-lactatemia. On contrary, some other found filter clearance only accounted for a very small part of total hemofilter's contribution to overall was negligible. The objective this study evaluate effects various doses veno-venous hemofiltration (CVVH) on plasma elimination in critically ill patients. Methods Patients were divided into three groups according their incipient...
Objective To evaluate the effects of dopamine (DA) and norepinephrine (NE) on hemodynamics oxygen metabolism tissue in patients with septic shock. Methods Forty sixty shock after abdominal surgery were assigned to groups DA NE randomly. They given or for 6 hours. Heart rate (HR), mean artery pressure (MAP), cardiac index (CI), stroke (SI), systemic vascular resistance (SVRI), mixed venous saturation (SvO2), early lactate clearance, urine volume per hour (UV) measured at end treatment....
Objective To improve the treat effect of orthotopic liver transplantation patients with severe sepsis. Methods Fif-ty-six post-surgery were enrolled in this study. Patients divided into two groups. One was non-OLT group (A group) and other OLT (B group). Besides general data, surveillance blood lactate, number failure organs, APACHE Ⅱand MODS recorded. 28-days survival rate follow-up checked. Results The mortality hospitalization 30% 57.6% group. level lactate at 1 st day increased...
Objective To explore the appropriate treatment opportunity and possible mechanism of ulinastatin combined with bone marrow mesenchymal stem cells (BMSCs) improving sepsis-induced acute lung injury. Methods The cecum end catheter continuous drainage (CASP) was used to establish septic model in 40 male SD rats weighing 180-220 g. The animals were randomly divided into 5 groups (n=8 each group): control (A), group (B), BMSCs at same time (group C), intervention 18 h after administration...