Danielle Carvalho Oliveira Coutinho

ORCID: 0000-0002-4724-194X
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About
Contact & Profiles
Research Areas
  • Dental Health and Care Utilization
  • Renin-Angiotensin System Studies
  • Receptor Mechanisms and Signaling
  • Dental Erosion and Treatment
  • Dental Anxiety and Anesthesia Techniques
  • Cardiac electrophysiology and arrhythmias
  • Retinal Diseases and Treatments
  • Orthodontics and Dentofacial Orthopedics
  • Mesenchymal stem cell research
  • Dental Radiography and Imaging
  • Ion channel regulation and function
  • Endodontics and Root Canal Treatments
  • Bone Tissue Engineering Materials
  • Vector-Borne Animal Diseases
  • Health and Medical Research Impacts
  • Injury Epidemiology and Prevention
  • Sex and Gender in Healthcare
  • Facial Trauma and Fracture Management
  • Hormonal Regulation and Hypertension
  • GABA and Rice Research
  • Retinopathy of Prematurity Studies
  • Cardiac Ischemia and Reperfusion
  • Tissue Engineering and Regenerative Medicine
  • Electrospun Nanofibers in Biomedical Applications
  • Pediatric Pain Management Techniques

Universidade Federal de Minas Gerais
2012-2023

National Institute of Science and Technology
2018

We have recently described a new peptide of the renin-angiotensin system, alamandine, derivative angiotensin-(1-7). Mas-related G protein-coupled receptor member D (MrgD) was identified as its receptor. Although similar cardioprotective effects alamandine to those angiotensin-(1-7) been described, significance this in heart function is still elusive. aimed evaluate functional role MrgD using MrgD-deficient mice. localized cardiomyocytes by immunofluorescence confocal microscopy....

10.1152/ajpheart.00075.2018 article EN AJP Heart and Circulatory Physiology 2018-10-19

The Mas protooncogene encodes a G protein-coupled receptor that has been described as functional for the cardioprotective fragment of renin-angiotensin system (RAS), Angiotensin (Ang)-(1-7). aim this current study was to evaluate responsiveness expression in hearts during different physiological and pathological conditions rats. Physical training considered condition, while isoproterenol-induced hypertrophy, myocardial infarction DOCA-salt model hypertension were used models heart injury....

10.1016/j.peptides.2012.03.022 article EN publisher-specific-oa Peptides 2012-04-06

Diabetic retinopathy (DR) is a serious complication of diabetes mellitus that may result in blindness. We evaluated the effects activation endogenous angiotensin converting enzyme (ACE) 2 on early stages DR. Rats were administered an intravenous injection streptozotocin to induce hyperglycemia. The ACE2 activator 1-[[2-(dimethylamino) ethyl] amino]-4-(hydroxymethyl)-7-[[(4-methylphenyl) sulfonyl] oxy]-9H-xanthone 9 (XNT) was by daily gavage. death retinal ganglion cells (RGC) histological...

10.1590/1414-431x20154583 article EN cc-by Brazilian Journal of Medical and Biological Research 2015-09-29

Diabetic patients present a high level of cardiac arrhythmias and risk sudden death. The renin–angiotensin system (RAS) plays key role in diabetes diseases. study aimed to evaluate whether an angiotensin-converting enzyme 2 (ACE2) activator, diminazene aceturate (DIZE), could improve the streptozotocin (STZ)-induced electrical changes ventricular repolarization hyperglycaemic rats. Hyperglycaemia was induced Wistar male rats with STZ (60 mg/kg/iv). After 4 weeks injection, were daily treated...

10.1093/europace/euu070 article EN EP Europace 2014-04-15

This study aimed to assess the anatomical and morphometric characteristics of main zygomaticofacial (ZFF), zygomaticoorbital (ZOF), zygomaticotemporal (ZTF) foramina in Brazilian dry skulls. 61, 69, 42 skulls for ZFF, ZOF, ZTF were evaluated by a single calibrated examiner format, transverse vertical diameters, distances from landmarks. Paired t test, Wilcoxon Pearson Spearman correlations used. Circular outline was predominant format ZFF ZTF, while oval most frequent ZOF. Median...

10.1097/scs.0000000000004530 article EN Journal of Craniofacial Surgery 2018-03-23

This study aimed to analyze the 100 most-cited papers in Dentistry, with a focus on female leadership dental research. Papers were retrieved from Web of Science Core Collection (WoS- CC) category 'Dentistry, Oral Surgery & Medicine'. Gender was assessed through WoS-CC, Scopus, ResearchGate, social media, institutional websites, and software that assigns gender according first names (https://genderapi.io). Characteristics authors roles retrieved, such as affiliation, publication history,...

10.1590/0103-644020230555959 article EN cc-by Brazilian Dental Journal 2023-01-01

Abstract
 Aim: This study assessed whether the presence of malocclusion had a negative impact on oral health-related quality life (OHRQoL) eight to ten-year-old children low socioeconomic status.
 Methods: A cross-sectional was conducted with total 111 children, ten years age, randomly selected from public schools Diamantina, MG, Brazil. The number determined by sample size calculation. Two calibrated examiners performed clinical examinations for diagnosis malocclusion, dental...

10.7308/aodontol/2020.56.e09 article EN Arquivos em Odontologia 2020-04-09

To conduct a morphometric evaluation of the incisive canal, adjacent structures, and their anatomic variations in Brazilian individuals.A retrospective study was conducted using sample 157 multislice computed tomography images adult individuals both sexes (20-96 years). The exam performed with RadiAnt DICOM Viewer 4.0.1 (64-bit) software that uses PACS standard for visualization medical dental images.The values length height thickness palatine bone plate, latero-lateral diameter foramen were...

10.1080/08869634.2021.1887610 article EN CRANIO® 2021-02-15

Cardiac complications are one of the main causes death in diabetes. Several studies have shown anti-diabetic effects bone marrow mesenchymal stromal cells (MSC). In present study, we investigated whether MSC-transplantation can revert cardiac dysfunction streptozotocin-induced diabetic rats and immunoregulatory MSC were examined. The divided three groups: Non-diabetic, Diabetic Diabetic-Treated that received 5x106 4 weeks after establishment Four MSC-therapy, systemic metabolic parameters,...

10.1161/res.113.suppl_1.a014 article EN Circulation Research 2013-08-01
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