A5046970123- Bone Tissue Engineering Materials
- Electrospun Nanofibers in Biomedical Applications
- Education Pedagogy and Practices
- Facial Trauma and Fracture Management
- Wound Healing and Treatments
- Bone Metabolism and Diseases
- Education and Digital Technologies
- Proteoglycans and glycosaminoglycans research
- biodegradable polymer synthesis and properties
- Orthopaedic implants and arthroplasty
- Tissue Engineering and Regenerative Medicine
- Renin-Angiotensin System Studies
- Dental Implant Techniques and Outcomes
- Spine and Intervertebral Disc Pathology
- Graphene and Nanomaterials Applications
- Science and Education Research
- Oral microbiology and periodontitis research
- Bone and Dental Protein Studies
- Connective tissue disorders research
- Anatomy and Medical Technology
- Education during COVID-19 pandemic
- Diabetic Foot Ulcer Assessment and Management
- Surgical Sutures and Adhesives
- Innovations in Medical Education
- Linguistics and Language Studies
Universidade Federal de Minas Gerais
2014-2024
Abstract Bioactive glasses (BGs) have shown great potential for tissue regeneration and their composition flexibility allows the incorporation of different ions with physiological activities therapeutic properties in glass network. Among many that could be incorporated, cobalt (Co) is a significant one, as it mimics hypoxia, triggering formation new blood vessels by vascular endothelial growth factor A ( VEGFA ), due to stabilizing effect on hypoxia inducible 1 subunit alpha HIF1A an...
We evaluated the effects of sodium hyaluronate (HY) and carbon nanotubes functionalized with HY (HY-CNT) on bone repair in tooth sockets diabetic rats.Diabetes was induced by streptozotocin (50 mg kg(-1) i.v.), were divided into normal control, treated (1%), HY-CNT (100 μg ml(-1)) groups. The analyzed according to percentage formation number cell nuclei.The trabeculae lower control animals (11.16 ± 5.10% vs 41.92 6.34% animals) after 14 days. Treating or significantly increased neoformed...
The aim of this study was to evaluate the effects sodium hyaluronate (HY), single-walled carbon nanotubes (SWCNTs) and HY-functionalized SWCNTs (HY-SWCNTs) on behavior primary osteoblasts, as well investigate deposition inorganic crystals titanium surfaces coated with these biocomposites. Primary osteoblasts were obtained from calvarial bones male newborn Wistar rats (5 for each cell extraction). We assessed viability using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide...
Resumo O objetivo deste estudo foi implementar e avaliar o impacto da elaboração de Mapas Conceituais (MC) como estratégia pedagógica no ensino-aprendizagem Anatomia Humana, uma das disciplinas do curso Fisioterapia Universidade Federal Minas Gerais. Participaram 298 alunos regularmente matriculados, ao longo seis semestres. A análise médias notas finais dos alunos, anteriores à ampliação projeto MC, demonstrou decréscimo dessas semestres, que revertido quando ensino MC implementado...
It has been reported that carbon nanotubes (CNTs) serve as nucleation sites for the deposition of bone matrix and cell proliferation. Here, we evaluated effects multi-walled CNTs (MWCNTs) on repair rat tibiae. Furthermore, because sodium hyaluronate (HY) accelerates restoration, associated with HY (HY-MWCNTs) in an attempt to boost repair. The defect was created by a 1.6-mm-diameter drill. After 7 14 days, tibiae were processed histological morphometric analyses. Immunohistochemistry used...
Diabetic foot ulcers (DFUs) are considered one of the most severe chronic complications diabetes and can lead to amputation in cases. In addition, bacterial infections diabetic wounds aggravate this scenario by threatening human health. Wound dressings made polymer matrices with embedded metal nanoparticles inhibit microorganism growth promote wound healing, although current clinical treatments for remain unsatisfactory. view, research reports synthesis characterization innovative hybrid...
It has been demonstrated that carbon nanotubes (CNTs) associated with sodium hyaluronate (HY-CNTs) accelerate bone repair in the tooth sockets of rats. Before clinical application HY-CNTs, it is important to assess their biocompatibility. Moreover, cardiac toxicity may be caused by translocation these particles blood stream. The aim this study was evaluate possible changes cardiovascular function male Wistar rats whose were treated either CNTs or HY-CNTs (100 μg/mL, 0.1 mL). Blood pressure...
Acute Kidney Injury (AKI) comprises a rapidly developed renal failure and is associated with high mortality rates. The Renin-Angiotensin System (RAS) plays pivotal role in AKI, as the over-active RAS axis exerts major deleterious effects disease progression. In this sense, conversion of Angiotensin II (Ang II) into Angiotensin-(1-7) (Ang-(1-7)) by Angiotensin-converting enzyme 2 (ACE2) utmost importance to prevent worse clinical outcomes. Previous studies reported beneficial oral diminazene...
The skin is the largest organ in human body that acts as a protective barrier from outside environment. Certain dermatological pathologies or significant lesions can result serious complications. Several studies have focused on development of tissue-engineered substitutes. In this study, new bilayer scaffold composed chitosan-gelatin membrane and chitosan-polyhydroxybutyrate (PHB) porous matrix was synthesized populated with adipose-derived mesenchymal stem cells (hASCs) to be potentially...
In this work, bionanocomposite membranes of hydroxyapatite nanoparticles (nHA) embedded in chitosan (CHI) or carboxymethyl-chitosan (CMC) matrices were chemically crosslinked with epichlorohydrin (ECH) for tuning their physicochemical and biological properties aiming at bone tissue regeneration. The choice CHI CMC biopolymer, as well the presence ECH crosslinker, affected nucleation growth processes nHA producing average diameters varying from 93 nm to 589 altered relative stability against...
Wound healing is important for skin after deep injuries or burns, which can lead to hospitalization, long-term morbidity, and mortality. In this field, tissue-engineered substitutes have therapy potential assist in the treatment of acute chronic wounds, where many requirements are still unmet. Hence, study, a novel type biocompatible ternary polymer hybrid hydrogel scaffold was designed produced through an entirely eco-friendly aqueous process composed carboxymethyl cellulose, chitosan,...
Os mapas conceituais surgiram a partir da Teoria Aprendizagem Significativa. Segundo essa teoria, o processo de aquisição do conhecimento ocorre quando aprendiz consegue conectar um pré-existente novo conceito. No presente estudo, foi analisado impacto uso dos como ferramenta pedagógica para potencializar aprendizado 161 estudantes das disciplinas Anatomia Humana cursos Fisioterapia e Terapia Ocupacional Universidade Federal Minas Gerais, no contexto projeto ensino ano 2022. Foram realizadas...