A5070676345- Neuropeptides and Animal Physiology
- Spacecraft and Cryogenic Technologies
- Rocket and propulsion systems research
- Atmospheric Ozone and Climate
- Low-power high-performance VLSI design
- Atmospheric chemistry and aerosols
- Spacecraft Design and Technology
- Space Satellite Systems and Control
- Astro and Planetary Science
- Receptor Mechanisms and Signaling
- Advancements in Semiconductor Devices and Circuit Design
- Neuroscience and Neuropharmacology Research
- Ion channel regulation and function
- Atmospheric aerosols and clouds
- VLSI and Analog Circuit Testing
- Synthesis of Organic Compounds
- Planetary Science and Exploration
- Inflammatory Bowel Disease
- Ionosphere and magnetosphere dynamics
- Dynamics and Control of Mechanical Systems
- VLSI and FPGA Design Techniques
- Synthesis and Biological Evaluation
- Semiconductor materials and devices
- Adaptive Control of Nonlinear Systems
- Inertial Sensor and Navigation
Toray Industries, Inc. (Japan)
2007-2023
Tokyo Metropolitan Tama Medical Center
2022-2023
Shiga University of Medical Science
2018-2022
Yasuda Women's University
2010-2020
Ogaki Municipal Hospital
2016-2020
Anjo Kosei Hospital
2020
Tosei General Hospital
2020
Nagoya University
1982-2020
Ichinomiya Municipal City Hospital
2020
Institute of Space and Astronautical Science
1997-2019
Oral activated factor XI (FXIa) inhibitors may modulate coagulation to prevent thromboembolic events without substantially increasing bleeding. We explored the pharmacodynamics, safety, and efficacy of oral FXIa inhibitor asundexian for secondary prevention after acute myocardial infarction (MI).We randomized 1601 patients with recent MI 10, 20, or 50 mg placebo once daily 6 12 months in a double-blind, placebo-controlled, phase 2, dose-ranging trial. Patients were within 5 days their...
The olfactory epithelium of fish contains three intermingled types receptor neurons (ORNs): ciliated, microvillous, and crypt. present experiments were undertaken to test whether the different ORNs respond classes odorants via families molecules G-proteins corresponding morphology ORN. In catfish, ciliated express OR-type receptors Galpha(olf). Microvillous are heterogeneous, with many expressing Galpha(q)/11, whereas crypt Galpha(o). Retrograde tracing show that project predominantly...
Extrinsic and intrinsic fiber connections of the telencephalic subdivisions Nieuwenhuys ('62) in a teleost, Sebastiscus marmoratus, were studied by means horseradish peroxidase (HRP) Fink-Heimer methods. The olfactory bulb projects bilaterally to area dorsalis pars posterior, ventralis ventralis, lateralis, intermedia, nucleus posterior tuberis Peter et al. ('75) receives fibers from ipsilateral centralis, dorsalis, supracommissuralis. Area sends numerous ventral region medialis, which...
This paper demonstrates that an 8T memory cell can be alternative design to a 6T in future highly-integrated SRAM, 45-nm process and later with large threshold-voltage variation. The proposed voltage-control scheme improves write margin read current, the write-back stabilizes unselected cells are applied SRAM. We verified low-voltage operation at 0.42 V 90-nm 64-Mb SRAM is possible under dynamic voltage scaling (DVS) environment.
Abstract The central fiber connections of the gustatory system (VII, IX, and X nerves) in crucian carp were examined by Fink‐Heimer method its modification. sensory recurrence roots VII enter brainstem separately terminate ipsilateral half facial lobe (L‐VII). Afferent fibers IX glossopharyngeal (L‐IX). Most afferent layer vagal (L‐X), which degenerating terminals occur some laminae. Some afferents project bilaterally to commissural nucleus Cajal. cutaneous component projects spinal...
Abstract The neuronal connections in the central gustatory system of crucian carp were examined by means degeneration and HRP methods. Cell morphology primary lobes was studied Golgi‐impregnated material. Medium‐sized neurons facial lobe emit axons which project to secondary nucleus. nucleus intermedius facialis Herrick ('05) projects bilaterally. Large send through spinal trigeminal tract terminate medial funicular In vagal lobs, second‐order for ascending projections are located...
Abstract The large majority of intraoral taste buds in goldfish are located on the gill arches and palatal organ, a muscular organ situated roof mouth. These innervated by branches vagus nerve which terminate laminated vagal lobe, itself being an enlargement special visceral sensory column medulla. tracer horseradish peroxidase (HRP) was used to determine connectivity various that innervate oropharyngeal gustatory surfaces. entire oral cavity is mapped onto lobe so anterior end most arch...
Tropolone (1) showed strong insecticidal activity on Tyrophagus putrescentiae and Dermatophagoides farinae. The effect of 1 both insects was stronger than that hinokitiol (2, 4-isopropyltropolone: major component Thujopsis dolabrata SIEB. et ZUCC. hondai MAKINO). compounds higher N,N-diethyl-m-toluamide (DEET), used as a positive control. Compound had potent against Coptotermes formosanus, although its much lower commercial chloropyrifos. Like 2, the inhibitory toward metalloproteases such...
Temporal fluctuations of spectral shapes have been observed in tip-enhanced Raman scattering (TERS) spectra adenine molecules. The TERS a nanocrystalline cluster molecules showed distinct temporal changes including peak frequencies and intensities extraordinary enhancements several peaks. fluctuating signals originate primarily from the first layer 5 nm thick cluster. possible origin is attributed to molecular orientation under metal-coated tip, which responsible for changing adsorption...
Abstract The primary gustatory sensory nuclei in catfish are grossly divisible into a vagal lobe and facial lobe. In this study, the reflex connections of each were determined with horseradish peroxidase (HRP) tracing methods. addition, order to determine loci morphology other brainstem cranial nerve nuclei, HRP was applied trigeminal, facial, glossopharyngeal, or vagus nerve. fibers terminate projects bilaterally posterior thalamic nucleus, superior secondary medial reticular formation...
This paper compares readout powers and operating frequencies among dual-port SRAMs: an 8T SRAM, 10T single-end differential SRAM. The conventional SRAM has the least transistor count, is most area efficient. However, power becomes large cycle time increases due to peripheral circuits. our proposed in which a dedicated inverter transmission gate are appended as read port. of reduced by 75% frequency increased 95%, over On other hand can operate fastest, because its small voltage 50 mV...
Although there are several reports of associations between body composition parameters and outcomes in patients with inflammatory bowel disease (IBD), it is not clear which muscle tissue and/or adipose most strongly affect outcomes. Therefore, this study sought to determine the such determined at level third lumbar vertebra (L3) on computed tomography (CT) images IBD patients.Subjects were who admitted our hospital underwent abdominal CT. The following assessed: skeletal index, psoas...
Optimal concentration of ustekinumab (UST) predicting endoscopic remission has not been fully investigated in Crohn's disease (CD). We aimed to identify the optimal UST trough levels clinical, laboratory and CD patients.Twenty-eight patients with were enrolled (27 by enteroscopy 1 colonoscopy). The activity was assessed using scoring system that applied Rutgeerts score observed intestine. Serum anti-UST antibodies (AUAs) determined in-house immunoassays.Endoscopic negatively correlated serum...
The primary olfactory projections of channel catfish Ictalurus punctatus have been examined with postmortem tracing by using either 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate or 1,1-dilinoleyl-3,3,3′,3′-tetramethylindocarbocyanine (DiI). Following DiI deposition into small areas in different parts the posterior bulb, sensory neurons always were labeled throughout epithelium. No obvious topographical mapping exists between epithelium and bulb. dye placements, however,...
Hinokitiol (beta-thujaplicin), beta-dolabrin and gamma-thujaplicin isolated from Thujopsis dolabrata SIEB. et ZUCC var hondai MAKINO showed antifungal activities against all of the wood-rotting fungi examined. The activity three compounds on Daedalea dickinsii IFO-4979 was especially strong, their minimum inhibitory concentration (MIC) values being 0.2 microg/ml. Their D. were as high that amphotericin B used a positive control. Three had strong insecticidal Tyrophagus putrescentiae...
Hepatic ischemia/reperfusion injury is a clinically important problem. While the mechanisms of initial event and subsequent neutrophil-dependent are somewhat understood, little known about regulation endogenous hepatoprotective effects on this injury. Interleukin 12 (IL-12) plays role in induction injury, but involvement interleukin 18 (IL-18) has not been clarified. Using murine model partial hepatic ischemia reperfusion, aim current study was to determine whether IL-18 up-regulated during...
Abstract The calcium ion plays an important role in some critical developmental events the nervous system, such as neurulation and neurite elongation. Therefore, intracellular calcium‐binding proteins calbindin‐D 28k (CaB) parvalbumin (PV) may be expressed these events. Accordingly, ontological expression of CaB PV was examined immunocytochemically spinal cord dorsal root ganglia (DRG) rat, order to evaluate relationship between expression, other During ontogenesis cord, CaB‐like...