A5100358513- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Synthesis of Organic Compounds
- Insect and Arachnid Ecology and Behavior
- Insect and Pesticide Research
- Protein Hydrolysis and Bioactive Peptides
- Ferroptosis and cancer prognosis
- RNA modifications and cancer
- Cancer Research and Treatments
- Enzyme Production and Characterization
- Marine Sponges and Natural Products
- Legionella and Acanthamoeba research
- Genetic Mapping and Diversity in Plants and Animals
- Retinal Development and Disorders
- Neuroscience of respiration and sleep
- Animal Nutrition and Physiology
- Sulfur Compounds in Biology
- Vibrio bacteria research studies
- Insect Utilization and Effects
- Meat and Animal Product Quality
- Insect behavior and control techniques
- Plant chemical constituents analysis
- Protein purification and stability
- Probiotics and Fermented Foods
Zhejiang Chinese Medical University
2023
Southern Medical University
2023
First Affiliated Hospital of Anhui Medical University
2023
Anhui Medical University
2023
Foshan Maternity and Child Health Care Hospital
2023
Fujian Medical University
2022
Fujian Provincial Cancer Hospital
2022
Wuhan University
2022
Renmin Hospital of Wuhan University
2022
Renji Hospital
2021
Following the publication of this paper, it was drawn to Editor's attention by a concerned reader that, regarding Transwell invasion assay experiments shown in Figs. 2D and 5F, 'Mimic control' panel Fig. appeared contain an overlapping section data with 'Blank' such that which were intended show results from differently performed had apparently been derived same original source. In addition, control western blot (GAPDH protein bands) blots 3C 5H same, although images inserted into these...
Aphids of the subtribe Aphidina are found mainly in North Temperate Zone. The relative lack diagnostic morphological characteristics has obscured identification species this group. However, DNA-based taxonomic methods can clarify relationships within Sequence variation a partial segment mitochondrial COI gene was highly effective for resolving Aphidina. Forty-five were correctly identified neighbor-joining tree. Mean intraspecific sequence divergence 0.17%, with range 0.00% to 1.54%....
MicroRNA (miR)‑217 serves a pivotal role in the progression of colorectal cancer, renal cell carcinoma and glioma, however, miR‑217 cervical cancer (CC) remains unclear. In present study, mechanism was explored. The mRNA expression mitogen‑activated protein kinase 1 (MAPK1) were assessed using reverse transcription‑quantitative polymerase chain reaction analysis. Cell Counting‑Kit 8, wound‑healing Transwell assays performed to detect viability, migration invasion, respectively. Apoptosis...
Repurposing of waste beer yeast (WBY) that a main by-product brewing industry has attracted considerable attention in recent years. In this study, the protein and polypeptide were extracted by ultrasonic-assisted extraction enzymatic hydrolysis with process optimization, which resulted maximum yield 73.94% 61.24%, respectively. Both WBY composed 17 Amino acids (AA) included seven essential amino (EAA), typically rich glutamic acid (Glu) (6.46% 6.13%) glycine (Gly) (5.26% 6.02%). AA score...
Retinal detachment disrupts the rod-bipolar synapse in outer plexiform layer by retraction of rod axons. We showed that breakage is due to RhoA activation whereas inhibition Rho kinase (ROCK), using Y27632, reduces synaptic damage. test whether ROCK inhibitor fasudil, used for other clinical applications, can prevent injury after detachment.Detachments were made pigs subretinal injection balanced salt solution (BSS) or fasudil (1, 10 mM). In some animals, was injected intravitreally...
Recent studies have elaborated on the concept that a number of microRNAs (miRNAs) potential effect pathogenesis and development Parkinson's disease (PD). PD is recognized as common progressive bradykinetic disorder results from death dopaminergic neurons in substantia nigra. The purpose this study was to explore whether microRNA-124 (miR-124) affected dopamine receptor (DAR) expression neuronal proliferation apoptosis 1-methyl-4-pheny-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse models...
MicroRNA‑34a (miR‑34a) serves as a tumor suppressor in number of different types cancer. The present study was performed to investigate the involvement miR‑34a bladder In study, downregulated patients with cancer compared healthy controls biopsies and plasma. Downregulation distinguished between controls. expression associated metastasis; however, not size. Transfection mimics upregulated phosphatase tensin homolog (PTEN) cells, decreased cell migration invasion. may inhibit invasion by...
Urinary microRNAs (miRNAs) may serve as promising biomarkers for non-invasive early detection of prostate cancer (PCa). We aimed to identify multi-miRNA urinary biomarker panel PCa.Urine samples from 83 PCa patients and 88 healthy control subjects in a Chinese population were collected miRNA profiling. The absolute expression 360 unique miRNAs measured each sample using highly sensitive robust RT-qPCR workflow. Candidate identified based on differential between controls. Multi-miRNA panels...
Summary Preparation of flavour peptides with microorganisms is an attractive choice for its large‐scale production. However, beefy meaty peptide (BMP), as a research hotspot in the field umami peptide, has been studied few microorganisms, and furthermore, safe preparation BMP not yet reported. In this study, multi‐copy (8BMP) was successfully expressed produced ‘generally recognized safe’ Bacillus subtilis ( B. ). Firstly, 8BMP potentially intense screened out based on molecular docking...
The structure of the title compound, anhydrofulvic acid, C14H10O7, a yellow acidic metabolite isolated from Paecilomyces sp. was determined by X-ray analysis. chromone ring system is essentially planar, with carboxylic acid group coplanar ring.
The ant-parasitizing genus Pseudacteon Coquillett is reported for the first time in China. Three new species, P. quadrisetalis Liu & Cai, sp. n., obtusatus n. and hexosetalis Wang, are described illustrated.
The molecules of the title compound, C11H10O5, are linked by a hydrogen bond involving acid H and carbonyl O atom dihydroisocoumarin unit into linear chain running along b axis monoclinic cell.
The poor reproductive performance of most local Chinese chickens limits the economic benefits and output related enterprises. As an excellent breed in China, Taihe black-bone silky fowl is urgent need our development utilization. In this study, we performed transcriptomic metabolomic analyses ovaries fowls at peak egg-laying period(PP) nesting period(NP) to reveal molecular mechanisms affecting performance. transcriptome, identified five key differentially expressed genes(DEGs) that may...
Abstract Background and aims Evidence has shown that miR-31 is a molecule associated with inflammation in different types of cells.However,the changes LPS-stimulated endothelial cells the effect this change expression on are unknown.This study sought to investigate how modulates permeability culture pulmonary microvascular (PMVECs). Methods It was discovered enhanced cell monolayer defined by lower TER higher FITC-dextran levels. Cell viability evaluated using an MTT assay, inflammatory...
Abstract A new species of the genus Aenigmatias Meinert, namely A. spatulatus sp. nov., is described from China. Another species, lubbochii (Verrall) redescribed, and record subfamily Aenigmatiinae China are documented. Voucher specimens including different types deposited with collection Liaoning Key Laboratory Urban Integrated Pest Management Ecological Security, Shenyang University, Shenyang, Province, Keywords: PhoridaeAenigmatiinae speciesnew recordChina
背景铜绿假单胞菌是常见的条件致病菌，易形成生物被膜，具有基因突变率高、耐药性强的特点。非同源末端连接是DNA双链断裂的主要修复途径之一，修复过程会导致DNA突变产生。 目的研究非同源末端连接对生物被膜中的铜绿假单胞菌基因突变率和耐药性的影响。 方法通过基因无痕敲除的方法构建PAO1菌株的ku基因缺失突变株Δku并构建其回补株。对比研究突变株和野生菌株生物被膜形成能力、生物被膜状态下各菌的基因突变率以及对抗生素的耐受性。通过荧光定量PCR检测生物被膜中PAO1菌株ku基因的表达水平。 结果各突变株生物被膜形成能力无显著差异；与野生菌株相比，突变株Δku在生物被膜中的基因突变率以及对环丙沙星和庆大霉素的最低抑菌浓度(minimum inhibitory concentration，MIC)下降。荧光定量PCR结果表明，ku基因在生物被膜形成早期转录水平有明显上调。 结论非同源末端连接修复途径对生物被膜中的铜绿假单胞菌基因突变率以及耐药性的提高有一定的作用。本研究将为后续进一步阐释铜绿假单胞菌耐药产生机制提供一定的理论依据。