A5101979073- Respiratory Support and Mechanisms
- Erythrocyte Function and Pathophysiology
- Traumatic Brain Injury and Neurovascular Disturbances
- MicroRNA in disease regulation
- Hedgehog Signaling Pathway Studies
- Cancer-related molecular mechanisms research
- Dental Trauma and Treatments
- Ion channel regulation and function
- Airway Management and Intubation Techniques
- dental development and anomalies
- Aortic aneurysm repair treatments
- Reconstructive Surgery and Microvascular Techniques
- Cancer Immunotherapy and Biomarkers
- Gas Dynamics and Kinetic Theory
- Thermoregulation and physiological responses
- Anesthesia and Neurotoxicity Research
- Immune Response and Inflammation
- Lung Cancer Treatments and Mutations
- Immune cells in cancer
- Aerospace Engineering and Energy Systems
- Epigenetics and DNA Methylation
- Spectroscopy Techniques in Biomedical and Chemical Research
- Radiation Dose and Imaging
- Head and Neck Cancer Studies
- Extracellular vesicles in disease
Central South University
2019-2023
Xi'an Jiaotong University
2023
First Affiliated Hospital of Anhui Medical University
2023
Anhui Medical University
2023
Second Xiangya Hospital of Central South University
2021
China Medical University
2021
People's Hospital of Kaizhou District
2019
Mechanical ventilation can induce or aggravate lung injury, which is termed ventilator-induced injury (VILI). Piezo1 a key element of the mechanotransduction process and transduce mechanical signals into biological by mediating Ca2+ influx, in turn regulates cytoskeletal remodeling stress alterations. We hypothesized that it plays an important role occurrence VILI, investigated underlying mechanisms.High tidal volume high magnitude cyclic stretch were performed on Sprague-Dawley rats, A549...
The supersonic parachute plays an important role in the descent and landing of Mars missions. Next-generation parachutes, such as disksail are alternatives to disk-gap-band (DGB) parachutes. Disksail parachutes have larger porous gaps smaller seams on canopy surface than DGB To date, influence mechanism or their locations performance systems Martian atmospheric conditions remains unclear. In this study, different models with based NASA’s were designed, aerodynamic characteristics geometric...
Abstract Background Secondary lung injury is the most common non-neurological complication after traumatic brain (TBI). Lung-protective ventilation (LPV) has been proven to improve perioperative oxygenation and compliance in some critical patients. This study aimed investigate whether intraoperative LPV could respiratory function prevent postoperative complications emergency TBI Methods Ninety patients were randomly allocated three groups (1:1:1): Group A, conventional mechanical [tidal...
Fentanyl is a strong anesthetic analgesic drug that plays important roles in many types of cancers. However, the role fentanyl papillary thyroid cancer (PTC) tumor development remains ambiguous. In this study, we aimed to investigate potential antitumor effects on PTC cell viability and invasion. Results counting kit-8 Transwell assays demonstrated treatment (5 ng/ml) reduced invasion two cells, TCP-1 BCPAP. Our data subsequently showed induced by increasing miR-204 expressions. Furthermore,...
Mechanical ventilation (MV) is a common way of respiratory support during general anesthesia and in critically ill patients. Recently people gradually realize that MV double-edged sword, which itself can also induce or aggravate lung injury as damage factor, is, ventilator induced (VILI). Current researches on the mechanisms VILI have changed from traditional barotrauma/volutrauma/atelectasis to biotrauma. In particular, it should be noted not only cause lung, but distant organs. This...
Objectives: To quantify the integrated levels of ACE2 and TMPRSS2, two well-recognized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) entry-related genes, to further identify key factors contributing SARS-CoV-2 susceptibility in head neck squamous cell carcinoma (HNSC). Methods: We developed a metric potential for tissue infected with ("TPSI") based on TMPRSS2 transcript compared TPSI between tumor matched normal tissues across 11 types. For analysis HNSC, weighted gene...
Abstract Background and aims Evidence has shown that miR-31 is a molecule associated with inflammation in different types of cells.However,the changes LPS-stimulated endothelial cells the effect this change expression on are unknown.This study sought to investigate how modulates permeability culture pulmonary microvascular (PMVECs). Methods It was discovered enhanced cell monolayer defined by lower TER higher FITC-dextran levels. Cell viability evaluated using an MTT assay, inflammatory...
In February 2018, a 67-year-old male patient with infected abdominal aortic aneurysm was admitted to the Department of Vascular Surgery Yantai Yuhuangding Hospital Affiliated Qingdao University Medical College. After admission, endovascular exclusion surgery, right iliac artery-double femoral artery vascular bypass+ aneurysmectomy+ stent removal and active anti-infective treatment were performed in department surgery. Seven days after prosthesis bypass surface skin red swollen, there...
Abstract Background : Secondary lung injury is the most common non-neurological complication after traumatic brain (TBI). Lung-protective ventilation (LPV) has been proven to improve perioperative oxygenation and compliance in some critical patients. This study aimed investigate whether intraoperative LPV could respiratory function prevent postoperative complications emergency TBI Methods Ninety patients were randomly allocated three groups (1:1:1): Group A, conventional mechanical [tidal...
Abstract Background: Mechanical ventilation can induce or aggravate lung injury, which is termed ventilator‑induced injury. Piezo1 a key element of the mechanotransduction process and transduce mechanical signals into biological by mediating Ca2+ influx, in turn regulates cytoskeletal remodeling stress alterations. We hypothesized that it plays an important role occurrence we investigated underlying mechanisms. Methods: High tidal volume high magnitude cyclic stretch were performed on...