A5006418801- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Fatty Acid Research and Health
- Lipid metabolism and biosynthesis
- Cholesterol and Lipid Metabolism
- Antioxidant Activity and Oxidative Stress
- Food Chemistry and Fat Analysis
- Phytochemicals and Antioxidant Activities
- Analytical Chemistry and Chromatography
- Biodiesel Production and Applications
- Edible Oils Quality and Analysis
- Advanced Glycation End Products research
- Natural Products and Biological Research
- Algal biology and biofuel production
- Ginseng Biological Effects and Applications
- Adipokines, Inflammation, and Metabolic Diseases
- Sirtuins and Resveratrol in Medicine
- Adipose Tissue and Metabolism
- Food Quality and Safety Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Natural Antidiabetic Agents Studies
- Phase Equilibria and Thermodynamics
- Plant biochemistry and biosynthesis
- MRI in cancer diagnosis
- Free Radicals and Antioxidants
Korea University
2016-2025
Bukwang Pharmaceutical (South Korea)
2022
Convergence
2022
Chonbuk National University Hospital
2000-2018
Catholic University of Daegu
2018
Wooridul Hospital
2018
Pukyong National University
2013
Chung-Ang University
2012
Rural Development Administration
2012
Ewha Womans University
2012
Decreased mitochondrial number and dysfunction in skeletal muscle are associated with obesity the progression of obesity-associated metabolic disorders. The specific aim current study was to investigate effects rutin on biogenesis high-fat diet-induced obese rats. Supplementation reduced body weight adipose tissue mass, despite equivalent energy intake (p < 0.05). Rutin significantly increased size DNA (mtDNA) content as well gene expression related biogenesis, such peroxisome...
Cardiovascular disease (CVD) is one of the main causes mortality worldwide, and dyslipidemia a major risk factor for CVD. Ginseng has been widely used in clinic to treat Ginsenoside Rg3, active components ginseng, reported exhibit antiobesity, antidiabetic, cardioprotective effects. However, effect ginsenoside Rg3 on hepatic lipid metabolism remains unclear. Therefore, we investigated whether would regulate with AMP-activated protein kinase (AMPK) activation HepG2 cells. significantly...
Abstract The aim of the present study was to evaluate effects green tea (‐)‐epigallocatechin‐3‐gallate (EGCG) on depletion accumulated fat in differentiated 3T3‐L1 adipocytes. Intracellular lipid accumulation decreased significantly after 24 h incubation with 10 µ m EGCG, while viability adipocytes reported be unaffected. Under same experimental conditions, amount glycerol released from cells into medium increased by EGCG. level mRNA analysed quantitative real‐time RT‐PCR. EGCG notably...
Abstract The concentrations of several nutraceutical lipid components [tocol ( i.e. tocopherol + tocotrienol) phytosterol, γ‐oryzanol, octacosanol, and squalene] in milled rice brown were determined. content decreased significantly p <0.05) as the degree milling increased, did total tocol content. Significant differences observed relative percentages α‐tocopherol, α‐tocotrienol, γ‐tocotrienol rice. β‐Sitosterol was most abundant sterol, representing 50–56% sterol all samples analyzed....
Abstract Capsaicin (8‐methyl‐ N ‐vanillyl‐6‐nonenamide) is a pungent ingredient of red peppers, and has been reported to reduce body weight gain adiposity in rodents. The present study investigated the effects capsaicin on lipid catabolism differentiated 3T3‐L1 adipocytes. decreased intracellular content concentration‐dependent manner. release glycerol into medium was increased by addition capsaicin. mRNA levels genes involved such as hormone sensitive lipase (HSL), carnitine palmitoyl...
Ginger is a plant whose rhizome used as spice or folk medicine. We aimed to investigate the effect of ginger root extract on obesity and inflammation in rats fed high-fat diet. Sprague-Dawley were divided into three groups either 45% diet (HF), HF + hot-water (WEG; 8 g/kg diet), high-hydrostatic pressure (HPG; diet) for 10 weeks. The HPG group had lower body weight white adipose tissue (WAT) mass compared group. Serum hepatic lipid levels lower, while fecal excretion was higher than that In...
Due to poor water solubility and high susceptibility chemical degradation, the applications of quercetin have been limited. This study investigated effects pH on formation quercetin-loaded nanoemulsion (NQ) compared hypocholesterolemic activity between NQ utilize as functional food ingredient. particle size exhibited a range 207–289 nm with polydispersity index (<0.47). The encapsulation efficiency increased stepwise from 56 92% 4.0 9.0. Good stability was achieved in 6.5–9.0 during...
In this study, we investigated the effects of germination on phytochemical content, antioxidant activity, and oxidative stability soybean oil. Soybeans were germinated for different periods (0, 2, 4, 6-days). The oil (GSO) contained more α-tocopherol, phytosterols, carotenoids, while there no significant differences in fatty acid content. particular, lutein accumulation was influenced by modulation phytoene synthase, lycopene ε-cyclase, β-cyclase genes during germination. Antioxidant...
Abstract Compositional changes of rice germ oils prepared at different roasting temperatures (160–180°C) and times (5–15 min) from were evaluated compared with those unroasted oil. The color development phosphorus content increased significantly as temperature time increased, whereas the FA compositions did not change time. Four phospholipid classes, i.e., PE, PI, PA PC, identified. PE had lowest stability under conditions. There no significant differences in γ‐oryzanol levels times....
Abstract Structured lipids were synthesized by acidolysis of perilla oil and caprylic acid using two lipases, Lipozyme RM IM from Rhizomucor miehei TL Thermomyces lanuginosa . Effects molar ratio, reaction time, temperature, enzyme load, solvent content on reactions studied. The ranged 0.0 (solvent‐free) to 85.3%. results showed that the incorporation increased in parallel with 49.0% 63.8% IM. After 24 h incubation n ‐hexane, acids incorporated 48.5 mol% 51.4 IM, respectively, whereas...
This study was performed to discover bifidobacteria isolated from human intestines that optimally convert linoleic acid (LA) conjugated (CLA) and optimize the culture conditions of milk fermentation. One hundred fifty neonatal were screened for CLA-producing ability, Bifidobacterium breve LMC 017 selected as it showed about 90% conversion free LA in MRS broth. The strain resistance at 0.5% microaerophillic conditions. When monolinolein (LA 90%) used a substrate CLA production, rate lower...
Phytosteryl ester synthesized with pinolenic acid (PLA) from pine nut oil is expected to have features of both phytosterol and PLA. In this study, lipase Candida rugosa (CRL) was immobilized then used optimize conditions for synthesis phytosteryl containing Lewatit VP OC 1600, a macroporous hydrophobic resin, selected as the best carrier, optimum condition immobilization CRL established. With prepared, fatty carried out. Parameters investigated were temperature, molar ratio (phytosterol...