A5041015056- Ruminant Nutrition and Digestive Physiology
- Systemic Sclerosis and Related Diseases
- Genetic and phenotypic traits in livestock
- Dermatologic Treatments and Research
- Agriculture, Soil, Plant Science
- Infant Nutrition and Health
- Animal Genetics and Reproduction
- Probiotics and Fermented Foods
- Systemic Lupus Erythematosus Research
- Protein Hydrolysis and Bioactive Peptides
- Natural product bioactivities and synthesis
- Rheumatoid Arthritis Research and Therapies
- Animal Nutrition and Physiology
- Medicinal Plants and Neuroprotection
- Body Contouring and Surgery
- Fatty Acid Research and Health
- Milk Quality and Mastitis in Dairy Cows
- Digestive system and related health
- Alzheimer's disease research and treatments
- Skin Diseases and Diabetes
- Food Quality and Safety Studies
- Effects of Environmental Stressors on Livestock
- Natural Products and Biological Research
- Nutrition, Health and Food Behavior
- Agroforestry and silvopastoral systems
Catholic University of Korea
2022-2024
Dankook University
2022
National Institute of Animal Science
2008-2019
Rural Development Administration
2017-2018
Jeonju University
2017
Ulsan National Institute of Science and Technology
2016
Chungbuk National University
2009-2011
Korea University
2008
A robust Ca doped PrBaMn<sub>2</sub>O<sub>5+δ</sub> with a layered perovskite shows not only good chemical and structural stability under reducing oxidizing conditions but also remarkable electrochemical performance in hydrogen hydrocarbon fuels for symmetrical solid oxide fuel cells electrode.
Objective The aim of the current study was to describe relationship between milk yield and lactation number, stage, length milking frequency in Korean Holstein dairy cows using an automatic system (AMS). Methods original data set consisted observations from April October 2016 780 cows, with a total 10,751 milkings. Each time cow milked by AMS during 24 h, management recorded identification numbers unit, being milking, date (kg) as measured meters installed on each lactation, (NoM). Lactation...
This study was performed to discover bifidobacteria isolated from human intestines that optimally convert linoleic acid (LA) conjugated (CLA) and optimize the culture conditions of milk fermentation. One hundred fifty neonatal were screened for CLA-producing ability, Bifidobacterium breve LMC 017 selected as it showed about 90% conversion free LA in MRS broth. The strain resistance at 0.5% microaerophillic conditions. When monolinolein (LA 90%) used a substrate CLA production, rate lower...
Abstract Background Rheumatoid arthritis (RA) is a progressive systemic autoimmune disease that characterized by infiltration of inflammatory cells into the hyperplastic synovial tissue, resulting in subsequent destruction adjacent articular cartilage and bone. Methotrexate (MTX), first conventional disease-modifying antirheumatic drug (DMARD), could alleviate damage RA implicated humoral cellular immune responses. However, MTX has several side effects, so efficient delivery low-dose...
Abstract Background MicroRNA (miRNA)-21-5p participates in various biological processes, including cancer and autoimmune diseases. However, its role the development of fibrosis vivo model systemic sclerosis (SSc) has not been reported. This study investigated effects miRNA-21a-5p overexpression inhibition on SSc using a bleomycin-induced mouse model. Methods A murine was induced by subcutaneously injecting 100 μg bleomycin dissolved 0.9% NaCl into C57BL/6 mice daily for 5 weeks. On days 14,...
Abstract Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by inflammation, microangiopathy, and progressive fibrosis in the skin internal organs. To evaluate pathophysiologic mechanisms efficacies of potential therapeutics for SSc, preclinical model recapitulating phenotypes needed. Here, we introduce novel animal SSc using immunodeficient mice injected with peripheral blood mononuclear cells (PBMCs) from patients. Human PBMCs acquired patients healthy controls were...
With the global demand for dairy protein consumption growing annually, there has been increasing activity in research field of synthesis and production. From a manipulation perspective, it is more difficult to use live cattle laboratory studies on production milk as well such casein, compared with using animals like rodents. Therefore, we aimed develop mouse model bovine mammary alveolar ducts laboratory-scale studies. We studied formation gland ductal structure by transplanting MAC-T cell...
This study was aimed to evaluate the in vitro effects of medicinal herb extracts (MHEs) on ruminal fermentation characteristics and inhibition protozoa reduce methane production rumen. A fistulated Hanwoo used as a donor rumen fluid. The MHEs (T1, Veratrum patulum; T2, Iris ensata var. spontanea; T3, Arisaema ringens; T4, Carduus crispus; T5, Pueraria thunbergiana) were added bottles containing fluid medium. Total volatile fatty acid (tVFA), total gas production, profiles, microbe...
Objective Glucose is an essential fuel in the energy metabolism and synthesis pathways of all mammalian cells. In lactating animals, glucose major precursor for lactose a substrate milk proteins fat mammary secretory (alveolar) epithelial However, clear utilization cells during lactogenesis still unknown, due to lack vitro analyzing models. Therefore, objective this study was test reliability alveolar (MAC-T) cell as model system. Methods Undifferentiated MAC-T were cultured three types...
Abstract Background EC-18, a synthetic monoacetyldiaglyceride, exhibits protective effects against lung inflammation, allergic asthma, and abdominal sepsis. However, there have been no investigations to determine whether EC-18 has preventive potential in autoimmune diseases, especially rheumatoid arthritis (RA). Methods To investigate the efficacy of on development RA, was administered collagen-induced (CIA) murine model disease severity level inflammatory cytokines joint were investigated....
This study was aimed to evaluate the stability of conjugated linoleic acids (CLAs) by nano-encapsulation against in vitro ruminal biohydrogenation microbial enzymatic conversion. CLAs (free fatty acid form CLA [CLA-FFA], nano-encapsulated CLA-FFA, triglyceride [CLA-TG], and CLA-TG) were used fermentation experiments. When Butyrivibrio fibrisolvens (B. fibrisolvens) incubated with CLA-FFAs, concentrations cis-9, trans-11 vaccenic (VA) slightly decreased increased nano-encapsulation,...
Objective This study was conducted to evaluate the effect of different levels total digestible nutrients (TDN) and sodium stearoyl-2-lactylate (SSL) supplementation on growth performance blood carcass characteristics in Hanwoo steers during early fattening period. Methods Sixty (average body weight, 333±36.4 kg) were randomly allotted 3 treatments, with twenty per treatment, ten pen a size 80 m2. Dietary treatments as follows: CON, basal diet; treatment (TRT) 0.5, 0.5% down-spec TDN 0.1%...
Systemic sclerosis (SS) is an autoimmune disease and pathological mechanisms of SS are unclear. In this study, we investigated the role T cells in progression using SKG mice humanized mice. have a spontaneous point mutation ZAP70. We induced scleroderma mouse model to assess whether cell-mediated immune responses induce SS. As result, found increased dermal thickness, fibrosis, lymphocyte infiltration skin tissue compared BALB/c (control). Also, blood cytokine level, including IL-4- IFN-α...
Abstract The gene associated with the retinoid–IFN-induced mortality-19 (GRIM-19) protein is a regulator of cell death regulatory that inhibits STAT3, which critical transcription factor for interleukin (IL)-17-producing T (Th17) cells and key integrator extracellular matrix accumulation in systemic sclerosis (SSc). This also component mitochondrial complex I, where it directly binds to STAT3 recruits mitochondria via importer Tom20. In this study, role GRIM19 its relationship SSc...