A5033010198- Antibiotic Resistance in Bacteria
- Pneumonia and Respiratory Infections
- Antibiotic Use and Resistance
- Streptococcal Infections and Treatments
- Bacterial Infections and Vaccines
- Bacterial Identification and Susceptibility Testing
- Yersinia bacterium, plague, ectoparasites research
- Pneumocystis jirovecii pneumonia detection and treatment
- Escherichia coli research studies
- Tuberculosis Research and Epidemiology
- Vibrio bacteria research studies
- Urinary Tract Infections Management
Smolensk State Medical University
2019-2024
Background: Acinetobacter species other than A. baumannii are becoming increasingly more important as opportunistic pathogens for humans. The primary aim of this study was to assess the prevalence, distribution, antimicrobial resistance patterns, and carbapenemase gene content clinical non-baumannii (Anb) isolates that were collected part a sentinel surveillance program bacterial infections in hospitalized patients. secondary evaluate performance MALDI-TOF MS systems species-level...
Objective. To study the prevalence and mechanisms of antibiotic resistance, including carbapenemase production, in clinical isolates Klebsiella pneumoniae Escherichia coli isolated different regions Russia as part sentinel multicenter surveillance 2020–2021, to explore population structure K. impact “high-risk clones” on resistance. Materials Methods. Consecutive, non-duplicate (n = 2503) E. 2055) from various specimens (blood, cerebrospinal fluid, respiratory samples, urine, wound...
Objective. Objectives. To assess the rates of antibiotic resistance, production acquired carbapenemases, genotypes and prevalence «international high-risk clones» among nosocomial strains Pseudomonas aeruginosa isolated in various regions Russia within «MARATHON 2015–2016» study. Materials Methods. A total 1006 non-duplicate isolates P. collected 44 hospitals from 25 cities 2015–2016 were studied. Species identification was performed by means MALDI-TOF mass-spectrometry.
Objective. To evaluate in vitro activity of various macrolide antibiotics against a current collection clinical isolates Streptococcus pneumoniae and pyogenes isolated from patients with community-acquired infections different regions the Russian Federation. Materials Methods. A total 350 infections, including 200 S. 150 pyogenes, were included study. further 16-member macrolides erythromycin-resistant (MIC ≥ 0.5 mg/L), retrospective 253 112 was tested. Susceptibility to antimicrobials...
Objective. To assess the in vitro activity of ceftazidime-avibactam against clinical Enterobacterales and Pseudomonas aeruginosa isolates various regions Russia based on results local susceptibility testing by disk diffusion method. Materials Methods. Overall, 160 laboratories located 61 Russian cities participated this surveillance during 2018-2020. All consecutive each participating laboratory were included study. Ceftazidime-avibactam was done disc-diffusion method accordance with current...
Objective. To study the antimicrobial susceptibility profile of Moraxella catarrhalis isolates from different regions Russia in 2010–2021. Materials and Methods. The included 352 M. isolated 11 cities (Volgograd, Irkutsk, Kazan, Kirov, Moscow, Murmansk, Perm, Seversk, Togliatti, Tomsk, Ulan-Ude) Identification was done by MALDI-TOF mass spectrometry. Antimicrobial testing determined broth microdilution method accordance with ISO 20776-1:2020. Interpretation results EUCAST guidelines...
Objective. To evaluate in vitro activity of biapenem and other clinically available carbapenems against Russian clinical isolates Enterobacterales, Pseudomonas aeruginosa и Acinetobacter spp., including with acquired fermentative mechanisms resistance to β-lactams. Materials Methods. A total 3139 Enterobacterales isolates, 793 P. 634 spp. from hospitalized patients 63 hospitals 35 cities were included the study during 2018-2019. Minimal inhibitory concentrations (MIC) for antimicrobials...
Objective. To determine in vitro activity of oral III generation cephalosporin cefpodoxime against clinical isolates Haemophilus influenzae, Streptococcus pneumoniae and pyogenes isolated from patients with community-acquired respiratory tract infections different regions the Russian Federation. Materials Methods. The study included bacterial pathogens outpatients hospitalized A total 558 were study, including 184 H. 186 S. 188 pyogenes. Species identification was performed using MALDI-TOF...