A5081065241- Fungal Biology and Applications
- Antibiotic Resistance in Bacteria
- Pediatric health and respiratory diseases
- Essential Oils and Antimicrobial Activity
- Plant-Microbe Interactions and Immunity
- Antibiotic Use and Resistance
- Yersinia bacterium, plague, ectoparasites research
- Microbial Natural Products and Biosynthesis
- Pneumonia and Respiratory Infections
- Probiotics and Fermented Foods
- Lichen and fungal ecology
- Biochemical and Molecular Research
- Plant and fungal interactions
- Studies on Chitinases and Chitosanases
- Algal biology and biofuel production
- Plant Pathogens and Fungal Diseases
- Phytochemistry and Bioactivity Studies
- Antimicrobial Resistance in Staphylococcus
- Nanocomposite Films for Food Packaging
- Marine Sponges and Natural Products
- Medicinal Plants and Neuroprotection
- Bacterial Infections and Vaccines
- Gut microbiota and health
- Quinazolinone synthesis and applications
- Bacterial Identification and Susceptibility Testing
Gause Institute of New Antibiotics Russian Academy of Medical Sciences
2022-2025
Sechenov University
2022
Central Research Institute of Epidemiology
2020
Ministry of Health of the Russian Federation
2020
Russian Scientific Center of Radiology and Surgical Technologies
2020
Federal State Budgetary Institution Russian Scientific Center of Roentgenoradiology
2019
Penza State University
2017
Objective. To assess rates of antimicrobial resistance and production the clinically important acquired mechanisms (extended spectrum beta-lactamases [ESBL] carbapenemases) in nosocomial strains Enterobacterales, to determine genotypes prevalence "international high-risk clones" among carbapenemase-producing Klebsiella pneumoniae isolated various Russian regions within "MARATHON 2015–2016" study. Materials Methods. A total 2786 non-duplicate isolates including 1316 K. 837 Escherichia coli 49...
In this study, two compounds have been isolated from the Arctic-derived fungus Penicillium chrysogenum INA 13460. Structural elucidation, performed using 2D NMR and HR-ESIMS data, has identified as stereoisomers of secalonic acids, dimeric tetrahydroxanthones. The absolute configurations these determined through conformational analysis circular dichroism spectroscopy. antimicrobial activity acids D F evaluated against a diverse range microorganisms, including Gram-positive...
Features of the biochemical adaptations alkaliphilic fungi to exist in extreme environments could promote production active antibiotic compounds with potential control microorganisms, causing infections associated health care. Thirty-eight and alkalitolerant Emericellopsis strains (E. alkalina, E. cf. maritima, terricola, sp.) isolated from different saline soda soils belonging marine, terrestrial, soil ecological clades were investigated for emericellipsin A (EmiA) biosynthesis, an...
Objective. Objectives. To assess the rates of antibiotic resistance and production acquired carbapenemases in nosocomial strains Acinetobacter spp., to determine genotypes prevalence "international high-risk clones" among baumannii isolated various regions Russia within "MARATHON 2015–2016" study. Materials Methods. A total 1005 non-duplicate isolates including 975 A. baumannii, collected 44 hospitals from 25 cities 2015– 2016 were studied.
Objective. Objectives. To assess the rates of antibiotic resistance, production acquired carbapenemases, genotypes and prevalence «international high-risk clones» among nosocomial strains Pseudomonas aeruginosa isolated in various regions Russia within «MARATHON 2015–2016» study. Materials Methods. A total 1006 non-duplicate isolates P. collected 44 hospitals from 25 cities 2015–2016 were studied. Species identification was performed by means MALDI-TOF mass-spectrometry.
Ribavirin and its analogues exhibit an in vitro antiproliferative effect cancer cells. In this work we studied the biological activities of a number oxymethyl derivatives ribavirin’s aglycon – 1,2,4-triazole-3-carboxamide. Oxymethyl 1,2,4-triazole-3-carboxamide with substitu-tions at fifth or first position triazole ring, were synthesized their antimicrobial effects assessed. For both series presence was inves-tigated case 1-oxymethyl shown potential against Gram-positive bacteria...
The aim of the present work was to explore insights into possibility cultivating mycelium edible basidiomycetes, i.e., Agaricus bisporus (J.E. Lange) Imbach, Lentinula edodes (Berk.) Pegler, and Pleurotus ostreatus (Jacq.) P. Kumm. on wastes produced from lavender, sage, mint, rose. To achieve this goal, we assessed growth development strains various substrates, a component analysis biomass strains, initial essential oil raw materials after processing, exposure basidial fungi strains....
We have performed a characterization of cultivated haloalkalitolerant fungi from the sediments Big Tambukan Lake in order to assess their biodiversity and antimicrobial activity. This saline, slightly alkaline lake is known as source therapeutic sulfide mud used sanatoria Caucasian Mineral Waters, Russia. Though data on bacteria algae observed this are available literature, adapted conditions lacking. The diversity was low represented by ascomycetes genera
The microscopic fungi Eremothecium ashbyi and E. gossypii are known for their ability to synthetize essential oil, which has a composition similar that of rose oil. development oil technology enables the production rose-scented products, demanded by pharmaceutical, food, perfumery industries. This study focuses on assessing in vitro cytotoxicity comparison with using combination methods two cell types (3T3 mouse fibroblast line bone-marrow-derived mesenchymal stromal cells (BM-MSCs))....
Ribavirin and its analogues exhibit an in vitro antiproliferative effect cancer cells. In this work, we studied the biological activities of a number alkyl/aryloxymethyl derivatives ribavirin’s aglycon—1,2,4-triazole-3-carboxamide. Alkyl/arylxymethyl 1,2,4-triazole-3-carboxamide with substitutions at fifth or first position triazole ring, were synthesized their antimicrobial effects assessed. For both series, presence was investigated, 1-alkyl/aryloxymethyl shown potential against...
The evaluation of antibiotic and chitinolytic activity in actinomycetes isolated from sod-podzolic soil (Albic Retisol (Loamic)) was carried out Moscow region (56°07′15″ N, 37°30′54″ E). Based on cultural morphological features analysis the 16S rRNA gene, strains were assigned to Streptomyces avidinii INA 01467 Micromonospora aurantiaca 01468. Evaluation actinomycete cultures showed that exhibit both antibacterial against gram-positive bacteria antifungal collection fungi Sac. cerevisiae...
Due to the emergence of antibiotic resistance in pathogenic microorganisms, it is urgent search for producers new antimicrobial metabolites. Actinomycetes are gram-positive mycelial bacteria that produce a large number antibiotics used medicine and agro-industrial complex. Currently, researchers focused on actinomycetes ecological niches such as freshwater marine reservoirs, zones with extreme natural conditions (permafrost soils, glaciers, desert, saline etc.). In this study, cultures were...