A5031178994- Pediatric health and respiratory diseases
- Ectopic Pregnancy Diagnosis and Management
- Neuropeptides and Animal Physiology
- Maternal and fetal healthcare
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Assisted Reproductive Technology and Twin Pregnancy
- Neurological Disorders and Treatments
- Pregnancy and preeclampsia studies
- Peptidase Inhibition and Analysis
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Chemical and Physical Studies
- Yersinia bacterium, plague, ectoparasites research
- Uterine Myomas and Treatments
- Bacterial Identification and Susceptibility Testing
- Preterm Birth and Chorioamnionitis
- GABA and Rice Research
- Antimicrobial Peptides and Activities
- Nicotinic Acetylcholine Receptors Study
- Allergic Rhinitis and Sensitization
- Fatty Acid Research and Health
- Biochemical effects in animals
- Hemophilia Treatment and Research
- Blood Coagulation and Thrombosis Mechanisms
Regional Clinical Hospital No 4
2018-2024
Altaiskiy State Nature Biosphere Reserve
2022
Altai State Medical University
2012
Russian Academy of Sciences
1996-1999
St Petersburg University
1999
Institute of Experimental Medicine
1990-1998
Academy of Medical Sciences
1994
Czech Academy of Sciences, Institute of Experimental Medicine
1994
Objective. To assess rates of antimicrobial resistance and production the clinically important acquired mechanisms (extended spectrum beta-lactamases [ESBL] carbapenemases) in nosocomial strains Enterobacterales, to determine genotypes prevalence "international high-risk clones" among carbapenemase-producing Klebsiella pneumoniae isolated various Russian regions within "MARATHON 2015–2016" study. Materials Methods. A total 2786 non-duplicate isolates including 1316 K. 837 Escherichia coli 49...
Objective. Objectives. To assess the rates of antibiotic resistance and production acquired carbapenemases in nosocomial strains Acinetobacter spp., to determine genotypes prevalence "international high-risk clones" among baumannii isolated various regions Russia within "MARATHON 2015–2016" study. Materials Methods. A total 1005 non-duplicate isolates including 975 A. baumannii, collected 44 hospitals from 25 cities 2015– 2016 were studied.
Objective. Objectives. To assess the rates of antibiotic resistance, production acquired carbapenemases, genotypes and prevalence «international high-risk clones» among nosocomial strains Pseudomonas aeruginosa isolated in various regions Russia within «MARATHON 2015–2016» study. Materials Methods. A total 1006 non-duplicate isolates P. collected 44 hospitals from 25 cities 2015–2016 were studied. Species identification was performed by means MALDI-TOF mass-spectrometry.
Combination antihypertensive therapy is required by most patients to achieve guideline-recommended blood pressure (BP) goals. This study assessed the effectiveness and tolerability of bisoprolol/perindopril (Bis/Per) single-pill combination (SPC) in Russian with hypertension coronary artery disease (CAD) treated routine clinical practice. STYLE (NCT03730116) was an open-label, uncontrolled, prospective observational conducted who were already receiving Bis/Per SPC, switched SPC from Bis or...
Objective. To evaluate antimicrobial susceptibility of Enterococcus spp. isolated from blood culture in patients with hematological malignancies. Materials and Methods. Antimicrobial 427 collected 10 hospitals 8 cities Russia 2002-2016 as part the multicenter study was tested by broth microdilution method [CLSI 2015]. Results. Among bloodstream pathogens there a prevalence E. faecium (78.2%), followed faecalis (19.7%) other (2.1%). A total 50 (15%) vancomycin-resistant (Vancomycin-resistant...
Introduction . The number of women with multiple pregnancy is increasing worldwide, especially in countries a high level health care, where assisted reproductive technologies are widely used. According to foreign studies, one third twins born as result Assisted Reproductive Technologies (ART), so only an increase can be predicted the future. main obstetric problem these pregnancies carrying. Objective : To identify predictors preterm birth patients order improve monitoring and prophylactic...
<h3></h3> В наших ранних сообщениях показано, что профилактическое применение терлипрессина позволяет снизить объем кровопотери при операции кесарева сечения (КС). Учитывая, препарат является мощным вазопрессором, остается открытым вопрос безопасности его местного применения у женщин с гипертензивными расстройствами во время беременности. <h3>ЦЕЛЬ ИССЛЕДОВАНИЯ</h3> Оценить безопасность беременных целью профилактики послеродовых кровотечений КС. <h3>МАТЕРИАЛ И МЕТОДЫ</h3> Обследовано 110...
The influence of amino acids, their mixtures, and peptides on the immune response, phagocytosis in vitro, CBA mice, broiler chickens, as well vitro ability listed preparations to protect animals' splenocytes from toxic action benzene aflatoxin B1 were studied. It was shown that acids (Asp, Glu, Val, Trp), acid mixtures (cerebrotysine, levamine, aviamine), dipeptides GluTrp LysAsp stimulate response SRBC at subcutaneous peroral application. thymopentin, thymosin α-1, peptide (thymosin...
Objective : to determine antimicrobial resistance of Enterococcus faecium and faecalis isolated from blood culture hematological patients during different study periods. Materials methods . Antimicrobial susceptibility spp., collected as part the multicenter was tested by broth microdilution method (USA Clinical Laboratory Standards Institute (CLSI), 2018), daptomycin Etest (bioMeriéux, France). High-level gentamicin (HLGR) high-level streptomycin (HLSR) performed agar dilution (CLSI (Oxoid,...
Objective. To study virulence genes in E. faecium and faecalis isolated from the blood cultures of patients with hematological diseases. Materials Methods. Virulence were studied strains culture four Russian hospitals (2002–2020). Susceptibility to vancomycin was determined by broth microdilution method (CLSI, 2022). (esp, hyl, asa1, cylA gelE) as well resistance (vanA, vanB vanD) Enterococcus spp. detected multiplex PCR. Results. A total 551 studied, them 440 (79.9%) 111 (20.1%) faecalis....
Objectives. This study aimed to clarify the role of intrauterine insemination (IUI) within clinical practice a regional infertility center. Methods. A retrospective, single-center, non-randomized was conducted on 1934 women with who sought evaluation and treatment at center between April 28, 2001, December 31, 2021. involved comparative analysis patients undergoing IUI either partner sperm or donor sperm. Various factors such as age, ovarian stimulation, number mature follicles (IUI...
The article is republished in order to expand the audience. was published earlier Akusherstvo i Ginekologiya (Russian Federation): Sukhikh GT, Serov VN, Artymuk NV, Andreeva MD, Bazina MI, Baranov II, Bashmakova Bezhenar VF, Belotserkovtseva LD, Geppe NA, Dolgushina Zaretskaya Zakharova IN, Zubkov VV, Enkova EV, Yesayan RM, Katkova NYu, Kvashnina Kogan IYu, Korsak VS, Krasnopolskaya KV, Kukarskaya Molchanova IV, Nazarenko TA, Pestova TI, Podzolkova NM, Saveljeva Sazonova AI, Semenov YuA,...
Prevention of postpartum haemorrhage is one the important tasks modern obstetrics, anesthesiology and intensive care. Objective. To assess efficacy safety terlipressin usage as a means development prevention during caesarean section in high-risk pregnant women. Patients methods. From February to December 2020, multicenter comprehensive cohort study, which 5 medical centers participated, was conducted. The study included 454 women who underwent were divided into two groups: control group I (n...
Severe and massive bleeding remains one of the main causes maternal mortality morbidity. The use terlipressin has proved to be effective in prevention postpartum haemorrhage high-risk group. Given that is a potent vasopressor, there are concerns about its parturient women with hypertension. Objective. To evaluate hemodynamic effects when it injected into myometrium during caesarean section. Patients methods. This publication continuation research work on effectiveness pregnant women, which...
The objective of the study: to investigate course infection, caused by A. baumannii, in patients intensive care units a general hospital. Methods. retrospective cohort study was conducted, which included 830 wards suffering from nosocomial infections Acinetobacter baumanii. bacterial diagnostics and drug susceptibility testing were performed using analyzer ADAGIO (Bio Rad, USA), Vitex 2 Compact 60 (bio Mariex, France) bacteriological for sterile blood cultures Bact Alar 3D60 France). As...