- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Organ Donation and Transplantation
- Renal Transplantation Outcomes and Treatments
- Gallbladder and Bile Duct Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Anomalies and Fetal Surgery
- Transplantation: Methods and Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Pancreatitis Pathology and Treatment
- COVID-19 Impact on Reproduction
- Abdominal vascular conditions and treatments
- MicroRNA in disease regulation
- Gastrointestinal disorders and treatments
- Hepatitis C virus research
- Cancer-related molecular mechanisms research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- COVID-19 Clinical Research Studies
- Pancreatic and Hepatic Oncology Research
- Hepatitis Viruses Studies and Epidemiology
- Renal and Vascular Pathologies
- Hepatitis B Virus Studies
- Central Venous Catheters and Hemodialysis
Max Super Speciality Hospital
2018-2025
Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences
2025
Blackpool Teaching Hospitals NHS Foundation Trust
2024
Bharath University
2023
Mayo Clinic in Florida
2023
Max Healthcare
2022-2023
Indraprastha Apollo Hospitals
2007-2019
Institute of Liver and Biliary Sciences
2019
Govind Ballabh Pant Hospital
2015
University of Delhi
2012
Increasing significance of tumor-stromal interaction in development and progression cancer implies that signaling molecules the tumor microenvironment (TME) might be effective therapeutic targets for hepatocellular carcinoma (HCC). Here, role microRNA miR-199a-3p regulation TME HCC has been investigated by several vitro vivo assays. Expression was observed significantly low tissues its overexpression remarkably inhibited growth metastasis to lung NOD-SCID mice. In restoration expression...
Post-liver transplant biliary strictures are a common cause of morbidity among patients who have undergone living donor liver transplantation (LDLT). Limited data available concerning the response rates to various treatment modalities and long-term outcomes for these individuals. This study was retrospective analysis prospectively collected database, including adult aged 18 years or older underwent LDLT between 2006 2022. Between 2022, total 3,550 transplantation. After applying exclusion...
<i>Objectives:</i> The presentation of choledochal cysts (CDCs) is altered by complications such as acute severe cholangitis, hepatolithiasis, spontaneous perforation, portal hypertension, pancreatitis, malignancy the biliary tract and previous surgery in form internal drainage cyst. management outcome complicated differ from that an uncomplicated CDC. This analysis our experience with CDCs. <i>Patients Methods:</i> One hundred forty-four patients CDCs were managed at...
Vascular complications continue to have a devastating effect on liver transplantation recipients, even though their nature, incidence, and outcome might actually changed with increasing experience proficiency in high-volume centers. The aim of this study was analyze the trends observed vascular changing protocols adult pediatric living donor over 10 years 2 time frames terms outcome. It is retrospective analysis 391 (group 1, January 2006 December 2010) 741 2, 2011 October 2013) patients....
Hepatic artery complications (HACs), such as a thrombosis or stenosis, are serious causes of morbidity and mortality after paediatric liver transplantation (LT). This study will investigate the incidence, current management practices outcomes in patients with HAC LT, including early late complications.
Living donor liver transplantation (LDLT) in obese patients raises concerns with regards to obtaining grafts of "adequate" graft-to-recipient weight ratio (GRWR) and the impact obesity on outcomes LDLT. LDLT weighing ≥100 kg were compared those <100 kg. Patients divided into 3 categories based GRWR they received. Groups 1, 2, included ≥0.8%, between 0.65% 0.8%, <0.65%, respectively. The 56 (6.5%) adult transplants performed 100 or more. Except for higher mean body mass index (35.8 versus...
In living donor liver transplant (LDLT), it is recommended to have a minimum graft recipient body weight ratio (GRBWR) 0.8 for good outcomes. Recent reports have, however, shown that outcomes can be obtained even with GRBWR less than 0.8. We hypothesized in patients receiving GRWR absolute rather may more relevant predicting outcome. Early post-transplant were assessed adult undergoing elective right lobe LDLT. Patients categorized as having (survival) or poor (mortality) A ROC curve was...
Background and aims Alcoholic liver disease (ALD) is the leading cause of cirrhosis related death worldwide. Excessive alcohol consumption resulting enhanced gut permeability which trigger sensitization inflammatory cells to bacterial endotoxins induces secretion cytokines, chemokines activation stellate cells, neutrophil infiltration hepatocyte injury followed by steatohepatitis, fibrosis cirrhosis. But all chronic alcoholics are not susceptible ALD. This study investigated causes...
Liver transplantation is considered to be the only curative treatment for decompensated liver disease. Shortage of allografts a major impediment widespread application this procedure. ABO-incompatible (ABO-I) grafts have been used successfully, thereby increasing living donor (LDLT) pool. However, ABO-I associated with complications like acute rejection, hepatic artery thrombosis, and higher biliary stricture rates, leading transplant failure, retransplantations, or sepsis-related...
Purpose A case of bilateral papilledema secondary to cerebral venous sinus thrombosis treated with Rituximab, an anti-CD20 monoclonal antibody. Methods 23 year old obese female a one week history blurred vision, headaches and vomiting presented papilledema. Her BCVA was 20/50 in right eye 20/200 the left severe reduction visual fields. Laboratory investigations revealed thrombocytopenia, prolonged prothrombin time (not reversed when mixed normal plasma) anticardiolipin antibodies. Besides,...