A5029536498- HIV, Drug Use, Sexual Risk
- Prenatal Substance Exposure Effects
- Opioid Use Disorder Treatment
- Substance Abuse Treatment and Outcomes
- HIV/AIDS Research and Interventions
- Cannabis and Cannabinoid Research
- HIV-related health complications and treatments
- Hepatitis C virus research
- Vaccine Coverage and Hesitancy
- Animal Virus Infections Studies
- Sex work and related issues
- Pharmaceutical Practices and Patient Outcomes
- Ethics and Legal Issues in Pediatric Healthcare
- Homelessness and Social Issues
- Healthcare professionals’ stress and burnout
- Mobile Health and mHealth Applications
- Global Maternal and Child Health
- Reproductive Health and Contraception
- Hepatitis B Virus Studies
- Biomedical and Engineering Education
- Social Media in Health Education
- Criminal Justice and Corrections Analysis
- Cervical Cancer and HPV Research
Boston University
2021-2024
Yale University
2018-2021
Rutgers Sexual and Reproductive Health and Rights
2015
To determine whether extended-release naltrexone (XR-NTX) would improve or maintain viral suppression (VS) among prisoners jail detainees with HIV and opioid use disorder (OUD) transitioning to the community.A 4-site, prospective randomized double-blind, placebo-controlled trial was conducted prison inmates OUD community from September 2010 through March 2016.Eligible participants (N = 93) were 2:1 receive 6 monthly injections of XR-NTX (n 66) placebo 27) starting at release observed for...
Medication treatment for opioid use disorder (OUD) (MOUD; buprenorphine and methadone) reduces overdose. Discontinuation of MOUD can quickly lead to relapse, overdose death. Few persons who initiate are retained on treatment, thus it is critical identify factors associated with retention.
rollout, availability, or incarcerated persons' preference.Distrust of staff is common in prisons, and how to encourage vaccination among persons should be considered.Our analysis only included states that reported full doses thus may not generalizable the US prison population.Better data transparency, including COVID-19 vaccinations by race ethnicity, needed evaluate prisons.
Acknowledging the needs and challenges of women with opioid use disorder is an essential step to reduce epidemic in United States. Efforts that can help include increasing psychosocial services address trauma, access medication treatment for disorder, reducing barriers stigma impede retention on treatment, addressing structural policy barriers. This commentary discusses reasons why women-focused necessary makes specific recommendations interventions, services, policies care improve among women.
Abstract Background In the United States, hepatitis C virus (HCV) diagnoses among reproductive-aged women are increasing amidst ongoing opioid and drug overdose epidemic. While previous studies document racial ethnic disparities in HCV testing treatment largely male populations, to our knowledge no national analyze these outcomes with use disorder (OUD). Methods We analyzed data from a cohort of (aged 15–44 years) diagnosed OUD captured TriNetX Research Network, network electronic health...
Abstract Background and Objectives We evaluated gender differences among persons initiating medications for opioid use disorder (MOUD). Methods Analyses of baseline assessments a study evaluating the impact MOUD on outcomes included: demographics, DSM‐5 diagnoses, depression severity, quality life (QoL), medication history ( N = 125). Results When compared to men, women had greater prevalence generalized anxiety posttraumatic stress disorders; worse psychological QoL. Women were less likely...
Abstract Background HIV prevalence is 3 times greater for those in the criminal justice system than general population, with an assumed increase sexual risk behaviors (SRBs) postrelease. viral suppression impacts transmission; however, studies of SRBs among persons leaving are limited, and no have examined relation to system. Methods Data were from 2 double-blind placebo-controlled trials extended-release naltrexone alcohol use or opioid disorder. Participants self-reported activity,...
Opioid use disorder (OUD) negatively impacts the HIV continuum of care for persons living with HIV. Medication treatment OUD (MOUD) may have differential biological effects in individuals and OUD. To address question modulation immune responses by MOUDs, we describe state art systems biology approaches to carry out first prospective, longitudinal study without infection initiating MOUD.A prospective cohort DSM-5 diagnosed who are methadone or buprenorphine is underway assess these...
Department of Internal Medicine, Section Infectious Diseases, AIDS Program, Yale School New Haven, CT (BEB, CF, SAS); Center for Interdisciplinary Research on AIDS, University Public Health, (SAS). Send correspondence to Sandra A. Springer, MD, Disease, 135 College Street, Suite 323, 06510. E-mail: [email protected]. Received 22 May, 2019 Accepted 16 July, The authors have no conflicts interest disclose.
The coronavirus disease 2019 pandemic accelerated the use of telehealth. However, this also exacerbated health care disparities for vulnerable populations.
The first human papillomavirus (HPV) vaccine was approved by the FDA in 2006, protecting against 2 carcinogenic types, 16 and 18. There is limited information about whether that vaccination may affect prevalence of other HPV types a community over time. Our study aimed to examine this issue. We used published data from Costa Rica Vaccine Trial. Women were vaccinated with either Cervarix® or hepatitis A (the control group). Based upon laboratory data, each these arms can be divided into naïve...
Abstract Background From 2000-2019 HCV prevalence among pregnant people increased 10-fold in the US, parallel to opioid epidemic, with consequences for children, whom perinatal transmission is most common route of infection. Direct-acting antivirals (DAAs) were first approved children ≥3 years old 2019. The aim this study was characterize care cascade and examine racial ethnic disparities access care. Methods Analyzing 2014-2022 data from TriNetX, a research network electronic health record...
Background Previous research has shown gender differences with respect to entry into medication treatment of substance use disorders (SUDs), yet few have examined among participants consented be treated extended-release naltrexone (XR-NTX). Understanding is critical developing interventions overcome barriers initiation and retention on for SUDs. Methods Data from two double-blind placebo-controlled trials XR-NTX persons HIV alcohol or opioid leaving the criminal justice system (CJS) were...
Objectives As opioid use increases, it remains important to assess factors that contribute injection drug risk behaviors, as sharing needles and other equipment contributes the spread of human immunodeficiency virus hepatitis C virus. Such risks may differ by sex injecting with others. The current study examined increased separately for men women. Methods People who inject drugs were recruited at an academic safety-net hospital reported recent use. Two main outcomes assessed: (1) behaviors...