A5089475092- Esophageal and GI Pathology
- Colorectal Cancer Screening and Detection
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Eosinophilic Esophagitis
- Inflammatory Bowel Disease
- Gastrointestinal disorders and treatments
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Surgical Treatments
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Clinical Nutrition and Gastroenterology
- Microscopic Colitis
- Colorectal Cancer Treatments and Studies
- Diverticular Disease and Complications
- Esophageal Cancer Research and Treatment
- Sociology and Education Studies
- Intestinal Malrotation and Obstruction Disorders
- Autoimmune and Inflammatory Disorders
- Linguistic Education and Pedagogy
- Biomedical and Chemical Research
- Asthma and respiratory diseases
- Mast cells and histamine
- Photoacoustic and Ultrasonic Imaging
- Urticaria and Related Conditions
Friedrich-Alexander-Universität Erlangen-Nürnberg
2007-2023
Universitätsklinikum Erlangen
2012-2023
Klinikum Kassel
2023
German Climate Computing Centre
2020
Malteser Waldkrankenhaus Erlangen
2016-2019
Institut für Soziale Arbeit
2018
Städtisches Klinikum Karlsruhe
2001
<b>Background and study aims:</b> In order to reduce time, costs, risks associated with resection of diminutive colorectal polyps, the American Society for Gastrointestinal Endoscopy (ASGE) recently proposed performance thresholds that new technologies should meet accurate real-time assessment histology polyps. this study, we prospectively assessed whether laser-induced fluorescence spectroscopy (LIFS), using WavSTAT4 optical biopsy system, can ASGE criteria. <b>Patients methods:</b> 27...
Introduction . Gastrointestinal bleeding represents the main indication for emergency endoscopy (EE). Lately, several hemostatic powders have been released to facilitate EE. Methods We evaluated all EE in which Hemospray was used as primary or salvage therapy, with regard short- and long-term hemostasis complications. Results conducted 677 474 patients (488 examinations 344 were upper GI endoscopies). applied during 35 27 (19 males), 33 2 lower endoscopy. It after previous treatment 21 (60%)...
Inflammatory bowel diseases (IBD) are characterized by mucosal inflammation and sequential fibrosis formation, but the exact role of hyperactive NLRP3 inflammasome in these processes is unclear. Thus, we studied expression function context IBD. We analysed intestinal immune cells fibroblasts from IBD patients NLRP3-associated gene via single-cell RNA sequencing microarray analyses. Furthermore, cytokine secretion inhibitor treated blood cells, as well proliferation, collagen production, cell...
Gastrointestinal bleeding and iron deficiency anaemia may cause severe symptoms require extensive diagnostics substantial amounts of health resources.This case report focuses on the clinical presentation a 22 year old patient with recurrent gastrointestinal from multilocular non-healing ulcers stomach, duodenum jejunum over period four years. Extensive gastroenterological allergological standard diagnostic procedures showed benign ulcerative lesions tissue eosinophilia, but no conclusive...
Background and aims Dye-less chromoendoscopy is an emerging technology for colorectal polyp characterization. Herein, we investigated whether the newly introduced I-scan optical enhancement (OE) can accurately predict histology in vivo real-time. Methods In this prospective three-phased study, 84 patients with 230 diminutive polyps were included. During first two study phases, five endoscopists assessed analysis of colour, surface vascular pattern under i-scan OE differentiate between...
The therapeutic management of patients with severe steroid-refractory ulcerative colitis still represents a critical clinical challenge. In this setting, cyclosporin is an effective and rapidly acting induction treatment that applied in combination maintenance agents like thiopurines or vedolizumab. Here, we present the case 33-year-old patient who refused surgical intervention previously demonstrated no long-term benefit to anti-TNF antibody, vedolizumab, cyclosporin, tofacitinib treatment....
Introduction Dementia is one of the most relevant widespread diseases, with a prevalence currently 50 million people dementia worldwide. The care will be major challenges for healthcare systems Digitalisation offers new possibilities to improve both and health outcomes research as fundament national planning. ‘Digital Registry Bavaria—digiDEM Bayern’ aims understanding complexity long-term progression current situation in Bavaria. Moreover, by offering digital services, digiDEM actively...
Zenker's diverticulum is a of the mucosa pharynx above cricopharyngeal muscle, which often causes clinical symptoms including dysphagia, regurgitation, cough, and halitosis [1]. Endoscopic therapy based on cutting septum between esophageal lumen. A variety endoscopic methods have been used for this procedure, laser, stapler, harmonic scalpel, argon plasma coagulation, needle-knives [1] [2] [3] [4]. Here, we describe use novel device, was originally developed submucosal dissection (ESD),...
Distal diminutive colorectal polyps are common and accurate endoscopic prediction of hyperplastic or adenomatous polyp histology could reduce procedural time, costs potential risks associated with the resection. Within this study we assessed whether digital chromoendoscopy can accurately predict distal according to ASGE PIVI statement. In prospective cohort study, 224 consecutive patients undergoing screening surveillance colonoscopy were included. Real time 121 was evaluated using...
Background: Up to the present date, treatment of recurrent chronic fistulas occurring with Crohn’s disease represents a challenging task for both internists and surgeons alike. Methods: Conservative methods using steroids, dietotherapy, antibiotics or immunosuppressive agents are not particularly effective in treating fistulas. Treatment anti-tumor necrosis factor-α (TNFα) antibodies results more remissions However, its use requires appropriate medical experience causes substantial costs....
Abstract Background and study aims Although several endoscopic techniques have been described for Zenker’s diverticulotomy, no standardized approach has established in clinical routine to date. This aimed assess the efficacy safety of diverticulotomy using Clutch Cutter. Patients methods Cricopharyngeal myotomy was performed six prospectively enrolled patients with symptomatic diverticulum, Procedural details such as duration, complications, technical success were recorded compared outcomes...
Although generally rising in incidence, intestinal tuberculosis is still rare western countries and due to unspecific manifestations mainly as ulcerations on endoscopy, diagnosis of challenging. Within this report, we describe a case severe radiologically endoscopically masquerading colorectal cancer with peritoneal carcinomatosis. Our exemplifies that needs be considered differential patients at risk undelayed sensitive central importance for avoiding unfavorable disease outcome.
Recent studies have analyzed the potential of advanced endoscopic imaging techniques for differentiating hyperplastic and adenomatous colorectal lesions. Latest resection now also allow treatment more staged lesions including early cancerous lesions.To assess i-scan technology to differentiate between polyps neoplasia.Consecutive patients undergoing colonoscopy at a tertiary referral center were included. After dedicated training, participating endoscopists underwent review 298 unknown...
With an incidence ranging between 0.3 % and 2.4 %, buried bumper syndrome (BBS) is a relatively rare complication after percutaneous endoscopic gastrostomy (PEG) in which the internal fixation device of cannula – retention migrates partially (incomplete BBS) or completely (complete into gastric wall with subsequent mucosal overgrowth [1] [2]. Management complete BBS can be challenging, variety devices have been described for treatment, including needle-knives, wire-guided papillotomes,...