William W. Lao

ORCID: 0000-0002-5266-5085
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About
Contact & Profiles
Research Areas
  • Reconstructive Surgery and Microvascular Techniques
  • Reconstructive Facial Surgery Techniques
  • Facial Rejuvenation and Surgery Techniques
  • Body Contouring and Surgery
  • Organ and Tissue Transplantation Research
  • Nasal Surgery and Airway Studies
  • Dermatologic Treatments and Research
  • Nutrition and Health in Aging
  • Orthopedic Surgery and Rehabilitation
  • Facial Nerve Paralysis Treatment and Research
  • Tracheal and airway disorders
  • Head and Neck Cancer Studies
  • Body Image and Dysmorphia Studies
  • Cancer Immunotherapy and Biomarkers
  • Digital Imaging in Medicine
  • Enhanced Recovery After Surgery
  • Clinical Nutrition and Gastroenterology
  • Inflammatory Biomarkers in Disease Prognosis
  • Ear Surgery and Otitis Media
  • Dupuytren's Contracture and Treatments
  • Hair Growth and Disorders
  • Nonmelanoma Skin Cancer Studies
  • Cerebral Venous Sinus Thrombosis
  • Bone fractures and treatments
  • Nuclear Structure and Function

Aesthetic Surgery Center
2020-2022

Showa University Fujigaoka Hospital
2022

Jikei University School of Medicine
2022

Chang Gung University
2018-2021

Chang Gung Memorial Hospital
2012-2021

Juntendo University Hospital
2021

Creative Commons
2021

Linkou Chang Gung Memorial Hospital
2014-2020

Duke University Hospital
2020

Duke Medical Center
2020

Increasing evidence indicates that inflammation plays a crucial role in cancer development. A novel scoring system based on albumin and the neutrophil-to-lymphocyte ratio (NLR) was developed incorporated into nomogram to create more accurate prognostic tool for oral cavity squamous cell carcinoma (OSCC) patients. retrospective review performed 613 consecutive patients undergoing ablative surgery OSCC between September 2005 December 2014. NLR were determined used calculate an albumin/NLR...

10.1038/s41598-018-31498-z article EN cc-by Scientific Reports 2018-08-24

To examine the ability of contact lenses coated with fimbrolides, inhibitors bacterial quorum sensing, to prevent microbial adhesion and their safety during short-term clinical assessment.A fimbrolide was covalently attached commercially available high Dk lenses. Subsequently Pseudomonas aeruginosa, Staphylococcus aureus, Serratia marcescens, or Acanthamoeba sp. were added control uncoated Lenses plus microbes incubated for 24 h, then washed thoroughly remove non-adherent microbes. macerated...

10.1097/opx.0b013e31816bea0f article EN Optometry and Vision Science 2008-04-28

Objectives This study aimed to investigate the potential prognostic role of oral cancer systemic inflammation score (SIS) based on serum albumin levels and lymphocyte‐to‐monocyte ratio in patients with squamous cell carcinoma (OSCC) after treatment. Study Design A retrospective cohort study. Setting Tertiary care center. Subjects Methods The involved 613 who were treated for OSCC between September 2005 December 2014. association SIS various clinicopathological features was investigated....

10.1177/0194599817751678 article EN Otolaryngology 2018-01-16

Background: Cephalocranial disproportion describes a state of volume mismatch between brain size and intracranial space. Nonsyndromic single-suture craniosynostosis patients can present with symptoms from elevated pressure because inadequate or delayed treatment. The purpose this study was to five sagittal synostosis children symptomatic cephalocranial treated cranial vault distraction osteogenesis. Methods: Asymmetric transverse internal osteogenesis performed preferentially expand the...

10.1097/prs.0b013e3181ef8f65 article EN Plastic & Reconstructive Surgery 2010-11-01

Objective: To describe a case of pneumolabyrinth secondary to tympanic membrane/ossicular trauma and the subsequent recovery sensorineural hearing loss managed with conservative measures. Patients: A 15-year-old boy presented an outside hospital signs symptoms acute loss, vertigo, tinnitus after penetrating injury his right membrane. In addition, computed tomography demonstrated air density within vestibule. Interventions: The patient was conservatively bed rest, avoidance straining,...

10.1097/mao.0b013e31815a9f2b article EN Otology & Neurotology 2007-12-01

Objectives/Hypothesis The role of tumor‐associated tissue eosinophilia (TATE) in oral cavity cancer remains quite controversial. This study investigated the potential TATE tongue squamous cell carcinoma (TSCC). Study Design Retrospective case series. Methods retrospectively enrolled 259 consecutive TSCC patients who underwent surgery between July 2004 and December 2015. Histopathological examinations for tumors were reviewed, association with different clinicopathological factors was...

10.1002/lary.27413 article EN The Laryngoscope 2018-08-10

Background The demand for aesthetic procedures continues to grow globally, particularly in East Asian countries. popularity of specific varies, however, depending on the particular geographical region being studied. This study aimed evaluate experiences and attitudes toward five countries/regions, including China, Japan, South Korea, Hong Kong, Taiwan. Methods To recruit participants, an online questionnaire was designed distributed social media networks between May 2015 March 2016....

10.5999/aps.2020.02565 article EN cc-by-nc Archives of Plastic Surgery 2021-11-01

Background: Abdominal wall, one of the most commonly transplanted composite tissues, is less researched and lacking animal models. Its clinical necessities were emphasized in multiple case series to reconstruct large abdominal defects. Previous models have only studied components wall transplant. We describe findings from a new model that more likely reflect transplantation. Methods: Full-thickness hemiabdominal flap was procured Brown Norway (BN) rats an orthotopic defect on Lewis rats....

10.1097/gox.0000000000000086 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2014-04-01

Abstract Background The purpose of this study was to elucidate the clinicopathological associations and molecular mechanisms karyopherin alpha 2 (KPNA2) in oral cavity squamous cell carcinoma (SCC) progression. Methods KPNA2 expressions were analyzed by immunohistochemistry enzyme‐linked immunosorbent assay 209 tissues 181 saliva samples, respectively. functions migration invasion examined KPNA2‐knowdown cells. matrix metalloproteinase (MMP) levels determined real‐time quantitative...

10.1002/hed.25145 article EN Head & Neck 2018-03-15

Free tissue transfer is a common method of reconstruction for various surgical defects. Many clinical assessment methods, including flap color monitoring and capillary refill time measurements, are commonly used to assess the microcirculation flap, yet there no objective tool available that can clear real-time visualization microcirculation. The purpose this study was use novel videocapillaroscope evaluate circulation changes on free skin surfaces while purposely clamping pedicle vessels.Ten...

10.1097/prs.0000000000009370 article EN Plastic & Reconstructive Surgery 2022-06-08

Background: Contemporary periorbital rejuvenation is undergoing a paradigm shift to an approach that prioritizes volume preservation and/or augmentation. However, the technical difficulties of using traditional fat grafting techniques in this area and distinct ethnic features make Asians especially challenging. Here, authors present their enhance periorbita outcomes. Methods: A retrospective chart review was performed for 33 consecutive patients who underwent microautologous transplantation...

10.1097/gox.0000000000002365 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2019-10-01

Abdominoplasty has been evolving since the 1960s with many technical innovations throughout years. It become one of most frequent and common procedures done in aesthetic plastic surgery, ultimate goal not only to remove excess tissue abdominal area but also achieve an trunk silhouette.The prime objective this article was describe our preferred approach for a full cosmetic abdominoplasty.We summarized all key aspects from shared surgical abdominoplasty. The describes collective experiences...

10.1097/sap.0000000000002639 article EN cc-by-nc-nd Annals of Plastic Surgery 2020-12-05

Abstract Background Replantation of a single digit at the distal phalanx level is not routinely performed since it technically challenging with questionable cost-effectiveness. The purpose this study was to analyze international microsurgeons' clinical decisions when faced common scenario. Methods A survey right-middle finger transverse complete amputation case conducted via online and paper questionnaires. Microsurgeons around world were invited provide their treatment recommendations. In...

10.1055/s-0039-1701013 article EN Journal of Reconstructive Microsurgery 2020-02-05

Background : Animal models and clinical cases of facial allotransplantation have been performed as a single stage procedure. A staged surgery might offer some advantages in selected cases. In this study, two‐stage face transplantation approach was on rat the feasibility safety were evaluated. Methods Brown Norway rats used donors Lewis recipients groups. total 33 hemiface‐scalp transplantations performed. Syngeneic orthotopic either one‐stage (one surgery; N = 3), local [heterothopic to neck...

10.1002/micr.22338 article EN Microsurgery 2014-10-21

Background The aim of this study is to evaluate osteonecrosis the jaw (ONJ) with extent marginal mandibulectomy. Methods Between January 2006 and December 2012, 3087 patients undergoing ablative resection were consecutively enrolled. Among them, 345 cases mandibulectomy retrospectively reviewed. Results occurrence ONJ was 5.51% associated body mass index, overall stage, diabetes, concomitant mandibulotomy, radiotherapy ( P = 0.023, 0.033, 0.009, 0.016, 0.006, respectively). As for bone...

10.1002/jso.24913 article EN Journal of Surgical Oncology 2017-11-22

Summary: Video-capillaroscopy is being explored as a potential tool for microsurgical flap monitoring. A detailed examination of the effect temperature on capillary changes using video-capillaroscopy yet to be investigated. We analyzed findings different skin areas often used harvest at normal body temperatures and lower temperatures. Skin capillaries lateral thigh, anterior forearm, mid-axillary line, abdomen, fingertips were observed in 20 healthy Japanese individuals. Further, ImageJ...

10.1097/gox.0000000000004265 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2022-04-01

The authors collectively reviewed their experiences in performing rhinoplasty North America, Asia, and South America categorized common undesirable features Eastern Western respective surgical algorithms. In rhinoplasty, the surgery is often reduction nature. proposed algorithm a dorsum-first, tip-second sequence to better suit need of this population. Meanwhile augmentation nature with extra materials needed build nose. opposite, tip-first dorsum-second sequence.

10.1097/sap.0000000000002617 article EN cc-by-nc-nd Annals of Plastic Surgery 2020-11-25

Summary: Indocyanine green, ultrasonography, and handheld Doppler can be used to evaluate blood flow at the donor recipient site during microvascular reconstruction. However, these methods do not provide direct visualization assessment of real-time flow. Video-capillaroscopy has been shown useful in clinical practice assess microcirculation rheumatologic disorders. In this report we video-capillaroscopy different tissue components involved surgery. Seven patients who underwent head neck...

10.1097/gox.0000000000004583 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2022-11-01

Summary: The orbicularis oculi muscle (OOM) is sometimes incorporated with the superficial musculoaponeurotic system (SMAS) flap to provide a stronger flap. While elevating OOM flap, it important avoid injury branches of zygomatic nerve. When nerve are identified during OOM-SMAS elevation, transverse was created preserve Postoperative follow-up 12 months. There no functional impairment in period. anatomical variations identified, incorporating can be raised inadvertent injury. Using this...

10.1097/gox.0000000000001961 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2018-10-01

The complete assignments of the 13C NMR resonances N-(alkanoyl)- and N-(3-oxoalkanoyl)-S-homoserine lactone are reported. These were made by comparison with values for N-butanoyl- S-homoserine lactone, a model compound whose structure was comprehensively established combination one-dimensional proton carbon spectra two-dimensional COSY, NOESY, HSQC HMBC experiments. Copyright © 1999 John Wiley & Sons, Ltd.

10.1002/(sici)1097-458x(199902)37:2<157::aid-mrc329>3.0.co;2-7 article EN Magnetic Resonance in Chemistry 1999-02-01
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