Nancy Fahim
A5040283251- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Infant Development and Preterm Care
- Dialysis and Renal Disease Management
- Birth, Development, and Health
- Neonatal Health and Biochemistry
- Congenital Diaphragmatic Hernia Studies
- Chronic Kidney Disease and Diabetes
- Pediatric Pain Management Techniques
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Pregnancy and preeclampsia studies
- Acute Kidney Injury Research
- Erythropoietin and Anemia Treatment
- Anesthesia and Neurotoxicity Research
- Blood transfusion and management
- Cerebral Palsy and Movement Disorders
University of Minnesota Children's Hospital
2020-2022
Washington University in St. Louis
2021
University of Minnesota
2020
High-dose erythropoietin has been shown to have a neuroprotective effect in preclinical models of neonatal brain injury, and phase 2 trials suggested possible efficacy; however, the benefits safety this therapy extremely preterm infants not established.
<h3>Importance</h3> Extremely preterm (EP) infants frequently receive opioids and/or benzodiazepines, but these drugs' association with neurodevelopmental outcomes is poorly understood. <h3>Objectives</h3> To describe the use of and benzodiazepines in EP during neonatal intensive care unit (NICU) hospitalization to explore at 2 years' corrected age. <h3>Design, Setting, Participants</h3> This cohort study was a secondary analysis data from Preterm Erythropoietin Neuroprotection (PENUT)...
<h3>Importance</h3> Extremely preterm infants are among the populations receiving highest levels of transfusions. Erythropoietin has not been recommended for premature because most studies have demonstrated a decrease in donor exposure. <h3>Objectives</h3> To determine whether high-dose erythropoietin given within 24 hours birth through postmenstrual age 32 completed weeks will need blood <h3>Design, Setting, and Participants</h3> The Preterm Neuroprotection Trial (PENUT) is randomized,...
<h3>Importance</h3> Practice variability exists in the use of corticosteroids to treat or prevent bronchopulmonary dysplasia extremely preterm infants, but there is limited information on longer-term impacts. <h3>Objective</h3> To describe infants and evaluate association with neurodevelopmental outcomes. <h3>Design, Setting, Participants</h3> This cohort study was a secondary analysis data from Preterm Erythropoietin Neuroprotection (PENUT) randomized clinical trial, conducted at 19...
<h3>Importance</h3> Understanding why and how extremely preterm infants die is important for practitioners caring these infants. <h3>Objective</h3> To examine risk factors, causes, timing, circumstances of death in a modern cohort <h3>Design, Setting, Participants</h3> A retrospective review enrolled the Preterm Erythropoietin Neuroprotection Trial between December 13, 2013, September 26, 2016, was conducted. total 941 born 24 0/7 27 6/7 weeks gestation at 19 US sites comprising 30 neonatal...
Background Endogenous erythropoietin (EPO) concentrations vary widely in preterm infants and may be associated with perinatal risk factors neurological outcomes. Erythropoietin is elevated fetal hypoxia but also a potential neuroprotectant. Methods In prospective study of 27 ≤ 30 weeks gestation, serum were measured during the first month life, on day 1 1, 2, 4, related to outcomes including retinopathy prematurity cerebral injury evaluated near term-equivalent post menstrual age using...