A5017367463- Schizophrenia research and treatment
- Mental Health Treatment and Access
- Workplace Health and Well-being
- Employment and Welfare Studies
- Psychiatric care and mental health services
- Child and Adolescent Psychosocial and Emotional Development
- Rheumatoid Arthritis Research and Therapies
- Inflammatory Bowel Disease
- Attention Deficit Hyperactivity Disorder
- Healthcare Decision-Making and Restraints
- Health, psychology, and well-being
- Substance Abuse Treatment and Outcomes
- Colorectal Cancer Screening and Detection
- Telemedicine and Telehealth Implementation
- Peripheral Neuropathies and Disorders
- Spondyloarthritis Studies and Treatments
- Pancreatic and Hepatic Oncology Research
- Digital Mental Health Interventions
- Microscopic Colitis
- Mental Health and Psychiatry
- Behavioral Health and Interventions
- Mental Health and Patient Involvement
- Cardiovascular Effects of Exercise
- Health Policy Implementation Science
- Helicobacter pylori-related gastroenterology studies
Mental Health Services
2016-2024
Copenhagen University Hospital
2023-2024
Capital Region of Denmark
2022-2024
Gentofte Hospital
2021-2023
Aarhus University Hospital
2021-2023
Sygehus Sønderjylland
2017-2023
University of Copenhagen
2021-2023
University of Southern Denmark
2016-2022
Central Denmark Region
2021
Aarhus University
2021
Summary Background Anti‐tumor necrosis factor‐α ( TNF ‐α) is used for the treatment of severe cases IBD , including Crohn's disease CD ) and ulcerative colitis UC ). However, one‐third patients do not respond to treatment. We have previously investigated whether single nucleotide polymorphisms SNP s) in genes involved inflammation were associated with response anti‐ therapy among or . Aim A new cohort was established replication previous findings identify s response. Methods Fifty‐three...
Individual placement and support (IPS) seems to be an effective vocational intervention for people with severe mental illness, but its effects have not yet been shown in the Danish welfare model. Also, may enhanced by adding cognitive remediation work-focused social skills training (IPS enhancements [IPSE]).To investigate of IPS vs IPSE service as usual (SAU) on a population individuals illness Denmark.This was investigator-initiated, 3-group, parallel, assessor-blinded randomized clinical...
Ankylosing spondylitis (AS) results from the combined effects of susceptibility genes and environmental factors. Polymorphisms in regulating inflammation may explain part heritability AS. Using a candidate gene approach this case-control study, 51 mainly functional single nucleotide polymorphisms (SNPs) were assessed 709 patients with AS 795 controls. Data on obtained DANBIO registry where all Denmark are monitored routine care during treatment conventional biologic disease modifying...
Treatment of alcohol use disorders (AUDs) is characterized by an adherence rate below 50%. Clinical research has found that patient enhances treatment effect; hence, health authorities, clinicians, and researchers strive to explore initiatives contributing patients receiving treatment. Concurrently, videoconferencing-based gaining ground within other addiction psychiatric areas.The aim this study was test whether optional videoconferencing increases effectiveness AUD in a randomized...
Chronic inflammatory diseases (CIDs), including Crohn’s disease and ulcerative colitis (inflammatory bowel diseases, IBD), rheumatoid arthritis, psoriasis, psoriatic spondyloarthritides, hidradenitis suppurativa, immune-mediated uveitis, are treated with biologics targeting the pro-inflammatory molecule tumour necrosis factor-α (TNF) (i.e., TNF inhibitors). Approximately one-third of patients do not respond to treatment. Genetics lifestyle may affect treatment results. The aims this...
Objective Stress-related disorders are common, associated with substantial individual suffering, and place a large economic burden on society. While treatment appears to be able reduce symptoms, evidence of interventions improve vocational outcomes is flimsy. Lack integration rehabilitation healthcare services has been suspected major potential barrier in return-to-work (RTW) processes; therefore, we aimed test the effectiveness such integration. Methods We randomized participants who were...
Objectives: Mental illness is often accompanied by poor physical health and shorter life expectancy. Second-generation antipsychotics (SGAs) are suspected of increasing cardiovascular risk, possibly through development metabolic syndrome (MetS), the risk adverse outcome even higher if obesity or aberration starts in childhood adolescence. Methods: Drug-naive adolescents were recruited after contact with an outpatient Psychosis Team. Changes relative to baseline body mass index (BMI), waist...
Introduction Chronic inflammatory diseases (CIDs) are frequently treated with biological medications, specifically tumour necrosis factor inhibitors (TNFi)). These medications inhibit the pro-inflammatory molecule TNF alpha, which has been strongly implicated in aetiology of these diseases. Up to one-third patients do not, however, respond biologics, and lifestyle factors assumed affect treatment outcomes. Little is known about effects dietary as a prognostic that may enable personalised...
Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are chronic, systemic, inflammatory diseases, primarily in the musculoskeletal system. Pain fatigue key symptoms of RA AS. Treatment presents a clinical challenge for several reasons, including progressive nature diseases involvement multiple pain mechanisms. Moreover, side effects treatment pose an implicit risk. Currently, no well-controlled studies have investigated how medical cannabis affects cognitive functions The present study...
Objective The aim of this study was to investigate an integrated mental healthcare and vocational rehabilitation intervention improve hasten the process return-to-work people on sick leave with anxiety depression. Methods In three-arm, randomised trial, participants were assigned (1) (INT), (2) improved (MHC) or (3) service as usual (SAU). primary outcome time measured at 12-month follow-up. secondary outcomes 6-month follow-up; levels anxiety, depression, stress symptoms, social...
To describe time-trends in incidence, characteristics, treatments, and survival pancreatic cancer patients Denmark during 1980–2019. A nationwide population-based cohort study of all Danish diagnosed with exocrine the period. Data was obtained from individual-level cross linkage between healthcare registries. We present descriptive characteristics estimates, which using Kaplan-Meier estimator Cox proportional hazards regression models. During period, 32,107 were cancer. In most recent...
Meta-analyses suggest that collaborative care (CC) improves symptoms of depression and anxiety. In CC, a manager collaborates with general practitioner (GP) to provide evidence-based care. Most CC research is from the US, focusing on depression. As results may not transfer other settings, we developed tested Danish CC-model (the Collabri-model) for depression, panic disorder, generalized anxiety social disorder in practice.Four cluster-randomized superiority trials evaluated effects CC. The...
Context : Sports injuries in athletes can lead to negative emotional responses terms of anger, anxiety, confusion, and sadness. Severe be understood as a stressful life event with increased levels psychological distress, but injury assessment rehabilitation typically focus on somatic symptoms. Objective The primary aim this study was estimate the prevalence depression stress measure self-rated health regular exercisers presenting sports medicine clinic musculoskeletal injury. secondary...