A5038677836- Intestinal Malrotation and Obstruction Disorders
- Congenital gastrointestinal and neural anomalies
- Soft tissue tumor case studies
- Digestive system and related health
- Neonatal Respiratory Health Research
- Pectus Deformity Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Sarcoma Diagnosis and Treatment
- Oral Health Pathology and Treatment
- Pancreatic function and diabetes
- Minimally Invasive Surgical Techniques
- Infant Development and Preterm Care
- Gastrointestinal motility and disorders
- Congenital Diaphragmatic Hernia Studies
- Cancer Cells and Metastasis
- Tumors and Oncological Cases
- Phagocytosis and Immune Regulation
- Reconstructive Surgery and Microvascular Techniques
- Cancer Research and Treatments
- Pleural and Pulmonary Diseases
- Diverticular Disease and Complications
- Ovarian cancer diagnosis and treatment
- Clinical Nutrition and Gastroenterology
- Oral microbiology and periodontitis research
- Bone Tumor Diagnosis and Treatments
University of Minnesota
2023
University of California, San Francisco
2020-2022
University of Southern California
2019-2021
Children's Hospital of Los Angeles
2018-2021
Johnson University
2020
Rutgers, The State University of New Jersey
2020
Columbia University
2012
Adverse microbial exposures might contribute to diabetogenesis. We hypothesized that clinical periodontal disease (a manifestation of in dysbiotic biofilms) would be related insulin resistance among diabetes-free participants. The roles inflammatory mediation and effect modification were also studied.
Models for enteric neuropathies, in which intestinal nerves are absent or injured, required to evaluate possible cell therapies. However, existing options, including transgenic mice, variable and fragile. Here immunocompromised mice were implanted with human pluripotent stem cell–derived tissue-engineered small intestine 10 weeks prior a second survival surgery nervous system precursor cells, saline controls, injected into the organoid–derived analyzed 4 later. Human implants as controls...
Introduction: Cell therapy and tissue engineering has recently emerged as a new option for short bowel syndrome (SBS) treatment, generating engineered small intestine (TESI) from organoid units (OU) biodegradable scaffolds. The recombinant human R-Spondin 1 (rhRSPO1) protein may be key player in this process due to its mitogenic activity intestinal stem cells. Objective: Aiming at optimizing the TESI formation advancing technology closer clinic, we evaluated effects of rhRSPO1 on OU culture...
Introduction: Splenectomy is common after trauma or hematologic disease, and alters immune protection against pathogens, which may lead to fulminant infection with high mortality. Yet the spleen has demonstrable regenerative capacity cells might be recovered reimplanted at time of injury excision avoid these risks. Methods: Tissue-engineered (TESp) was generated from ActinGFP mice (mTESp) human donor (hTESp) through implantation organoid units (spleen OU), in NOD/SCID concurrent splenectomy,...
Abdominal lipoblastomas are uncommon soft tissue tumors in children and rarely arise from the mesentery. Due to intraabdominal location slow growth, these masses can go unnoticed for long periods of time often found on surgical exploration. We present a case 12-year-old male with years abdominal distension accompanied by new onset early satiety that was have an intra-abdominal mass. He underwent exploratory laparotomy revealing large 33 x 27 15 cm rubbery mesenteric mass displacing entire...
Background: Slipping rib syndrome (SRS) is an often unrecognized cause of lower chest and upper abdominal pain in children adolescents. Surgical resection the cartilaginous portions slipping provides permanent relief, with standard surgical approach being open resection. A minimally invasive has not been reported previously; we report a novel laparoscopic technique for treatment SRS satisfactory results. Materials Methods: retrospective review all consecutive pediatric patients who underwent...
Precocious puberty in an infant is alarming and infrequent finding, making the differential diagnosis difficult for practitioners. secondary to a sclerosing stromal tumor (SST) of ovary rare. We present case child that began precocious at 3 months age including development breast buds, pubic hair, growth spurt, menarche 5 days prior presenting pediatric endocrinology 10 months. She underwent right salpingo-oophorectomy which demonstrated soft tissue mass occupying almost entire with tan-pink...
Background and Aim: Congenital diaphragmatic hernia (CDH) is a rare defect often associated with pulmonary hypoplasia abnormal vascular development. Even after successful repair, disease may persist into adulthood. Impaired motility lead to compromised respiratory function long index repair. This study investigates whether novel ultrasound measurement, the excursion ratio, can be simple non-invasive method evaluate routine motion CDH it correlates adverse surgical outcomes. Materials...
Mutations in the paired-like homeobox 2 b (PHOX2B) gene are associated with congenital central hypoventilation syndrome (CCHS), which is a rare condition both autonomic dysregulation and an enteric neuropathy may occur. The majority of patients CCHS have polyalanine repeat mutation (PARM) PHOX2B, but minority nonpolyalanine mutations (NPARMs), some been localized to exon 1. A PHOX2B-Y14X nonsense previously generated human pluripotent stem cell (hPSC) line results NH2-terminus truncated...