A5034463788- Reconstructive Surgery and Microvascular Techniques
- Glaucoma and retinal disorders
- Ophthalmology and Visual Impairment Studies
- Retinal Imaging and Analysis
- Reconstructive Facial Surgery Techniques
- Retinal Diseases and Treatments
- Corneal surgery and disorders
- Connexins and lens biology
- Corneal Surgery and Treatments
- Ocular Surface and Contact Lens
- Advanced Glycation End Products research
- Retinal and Macular Surgery
- Organ and Tissue Transplantation Research
- Bone fractures and treatments
- Facial Nerve Paralysis Treatment and Research
- Cell Adhesion Molecules Research
- Retinopathy of Prematurity Studies
- Bone Tumor Diagnosis and Treatments
- Ocular Infections and Treatments
- Ocular Oncology and Treatments
- Cancer-related molecular mechanisms research
- interferon and immune responses
- Flame retardant materials and properties
- Mangiferin and Mango Extracts
- Shoulder and Clavicle Injuries
Affiliated Hospital of Southwest Medical University
2020-2025
China Ocean Shipping (China)
2024
Southwest Medical University
2013-2024
Qingdao University
2024
Ocean University of China
2018
Central South University
2014-2017
First Affiliated Hospital of Sichuan Medical University
2013-2015
Xiangya Hospital Central South University
2013-2014
Tianjin Medical University
2014
Fuzhou Second Hospital
2010
Diabetic retinopathy (DR) is one of the serious complications that occurs in diabetic patients frequently causes blindness. Long noncoding RNAs (lncRNAs) have been associated with DR pathology. This study aimed to determine underlying mechanism lncRNA maternally expressed gene 3 (MEG3) association DNA methyltransferase 1 (DNMT1) endothelial-mesenchymal transition (endMT) DR. A rat model was induced by streptozotocin (STZ) injection, and a high-glucose (HG)-induced cell established exposing...
Abstract Background Retinal disorders cause substantial visual burden globally. Accurate estimates of the vision loss due to retinal diseases are pivotal inform optimal eye health care planning and allocation medical resources. The purpose this study is describe proportion impairment blindness caused by major in China. Methods A nationwide register-based vitreoretinal disease covering all 31 provinces (51 treating centres) mainland total 28 320 adults diagnosed with were included....
ABSTRACT Our previous studies have identified mitsugumin 53 (MG53) as a novel regulator for angiogenesis by directly entering endothelial cells and modulating focal adhesion kinase (FAK) activation, but little is known about how rhMG53 taken up mediates cell movement. In the present study, we demonstrated that knockdown of caveolin‐1 clathrin inhibitor, pitstop‐2, both significantly reduced entry into cells, indicating caveolae‐dependent clathrin‐dependent endocytosis during this process....
Mangiferin is a prominent active component that can be derived from several traditional herbs, including <em>Mangifera indica </em>L., <em>Anemarrhena asphodeloides</em> Bge., and <em>Belamcanda chinensis</em> (L.) DC., which displays antidiabetic properties. Diabetic retinopathy (DR), serious complication caused by diabetes, the leading cause of blindness. The present study aimed to evaluate beneficial effects mangiferin on high glucose (HG)/hypoxia‑induced rat retinal capillary endothelial...
Iatrogenic subclavian arteriovenous fistula is rare and has not been reported as a complication of plate osteosynthesis clavicle fracture. This article describes the first case iatrogenic caused by osteosynthesis. A 36-year-old man sustained right middle fracture in an injury underwent open reduction internal fixation with clavicular compression 3 days later local hospital. On second postoperative day, pulsatile mass thrill were detected at supraclavicular region. The patient was discharged...
To address challenges in screening for chronic kidney disease (CKD), we devised a deep learning-based CKD model named UWF-CKDS. It utilizes ultra-wide-field (UWF) fundus images to predict the presence of CKD. We validated with data from 23 tertiary hospitals across China. Retinal vessels and retinal microvascular parameters (RMPs) were extracted enhance interpretability, which revealed significant correlation between renal function RMPs. UWF-CKDS, utilizing UWF images, RMPs, relevant medical...
Development and validation of a deep learning algorithm to automatically identify locate epiretinal memberane (ERM) regions in OCT images.OCT images 468 eyes were retrospectively collected from total 404 ERM patients. One expert manually annotated the for all images. A 422 (90%) remainig 46 (10%) used as training dataset validation, respectively. senior one junior clinician read The diagnostic results compared.The accurately segmented located image-level accuracy was 95.65%, region-level...
Diabetic retinopathy (DR) is a serious retinal vascular disease that affects many individuals in their prime working years. The present research aimed at whether and how LOC681216 (LNC-216) involved dysfunction under diabetic conditions.
Study Design. An animal experimental study was designed to investigate the efficacy of combined magnetic fields (CMF) treatment and nano-hydroxyapatite (HA) coating in biphasic calcium phosphate (BCP) graft posterolateral lumbar fusion. Objective. To evaluate effects CMF nano-HA/BCP their combination effect Summary Background Data. Enhancement artificial bone bioeffects could improve spinal fusion outcomes. The integration is vital fusion, nano-HA coating, were reported as effective methods...
Melphalan-based intra-arterial chemotherapy was considered an innovative treatment for retinoblastoma patients because high rates of globe salvage could be obtained. Now it has been widely applied primary or secondary retinoblastoma. This meta-analysis summarizes the most up-to-date evidence regarding safety and effectiveness melphalan-based in The authors searched PubMed, EMBASE, Web Science electronic databases studies investigating Studies reporting outcomes complications would included....
<b>Background</b> The authors presented their clinical experience and demonstrated surgical methods for reconstructing complex bone soft tissue defects of the hand by using modified chimeric radial collateral artery perforator flaps. <b>Methods</b> Surgical procedures that employed 16 flaps 3 dual paddle were performed in patients. Among patients, eight had metacarpal bones phalanx bones. created with a skin humeral segments independent perforators. ranged size from 5.5 × 2.0 to 7.5 4.5 cm,...
BACKGROUND The current research work aimed to explore the protective role of myricetin against cataractogenesis in humans, terms its anti-apoptotic potential. MATERIAL AND METHODS Human eye lens epithelial cells were exposed oxidative stress by treating with hydrogen peroxide (H₂O₂). levels superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH) determined using standard detection kits. DAPI (4',6-diamidino-2-phenylindole), AO/EB (acridine orange/ethidium bromide) Annexin...
The paper aims to improve the operative technique of osteomyocutaneous iliac crest flap harvesting, further minimise morbidity donor site, and effect recipient site reconstruction. From March 2005 2011, 55 cases harvested by different methods were performed reconstruct defects extremities. Twenty-nine reconstructed with a traditional deep circumflex artery osteomusculocutaneous flap. Twenty-six repaired modified flaps. In 29 DCIA flap, two showed injured lateral femoral cutaneous nerve....
<b>Objective</b> We present our clinical experience and demonstrate surgical methods to reconstruct the thumb by using a wraparound chimeric radial collateral artery perforator flap. <b>Methods</b> Surgical procedures were performed in 12 patients. Flaps with skin paddle humeral bone segment created on basis of independent perforators. The sizes flaps fragments ranged from 5.5 cm × 2.0 7.5 4.5 1.5 0.5 cm, respectively. flap pedicle was divided ligated above level at which into anterior...