A5064899978- Gut microbiota and health
- Animal Nutrition and Physiology
- Probiotics and Fermented Foods
- Diabetic Foot Ulcer Assessment and Management
- Clostridium difficile and Clostridium perfringens research
- Wound Healing and Treatments
- Hippo pathway signaling and YAP/TAZ
- Gastrointestinal motility and disorders
- Analytical chemistry methods development
- Digestive system and related health
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- Hydrogen's biological and therapeutic effects
- Medical Research and Treatments
- Analytical Chemistry and Chromatography
- Diet and metabolism studies
- Mesenchymal stem cell research
- Heavy Metal Exposure and Toxicity
- Cancer-related Molecular Pathways
- Viral gastroenteritis research and epidemiology
- Hedgehog Signaling Pathway Studies
- Cancer Research and Treatments
- Effects and risks of endocrine disrupting chemicals
- Developmental Biology and Gene Regulation
- Aortic Thrombus and Embolism
First Affiliated Hospital of Zhengzhou University
2025
Institute of Subtropical Agriculture
2017-2024
Chinese Academy of Sciences
2017-2024
Hunan First Normal University
2017-2024
Beijing Institute of Optoelectronic Technology
2023
Beijing Institute of Technology
2010-2023
Huazhong University of Science and Technology
2004-2023
Gannan Medical University
2018-2022
Zhejiang Chinese Medical University
2022
Hunan Normal University
2009-2019
Essential oils (EO) are promising feed additives for their antibacterial, antioxidant, and immune-enhancing abilities with low toxicity. Carvacrol, thymol, cinnamaldehyde commonly used to synthesize EO. However, few studies focus on combining these three EO in early-weaned piglets. In the present study, 24 piglets weaned at 21 d of age were randomly divided into 2 groups (6 replicate pens per group, pen). The fed a basal diet (the control group) supplemented 400 mg/kg (a blend consisting...
Coronary Artery Calcification (CAC) is a major risk factor for various cardiovascular diseases. Low-Density Lipoprotein Cholesterol (LDL-C) significant in atherosclerotic diseases and usually elevated patients with Type 2 Diabetes Mellitus (T2DM). However, the association between LDL-C levels incident CAC asymptomatic T2DM remains unclear. This study single-center retrospective cohort conducted from January 2018 to December 2023, including 2,631 who underwent regular health screenings. All...
Lysozyme has been studied as a potential alternative to antibiotics for animals in recent years. The aim of this study was evaluate the effect dietary lysozyme on growth performance, serum biochemical parameters, immune response and gut health growing pigs.A total 216 pigs (19.81 ± 0.47 kg) were fed diets supplemented with colistin sulfate at 20 mg kg-1 (control), or 50 (L50) 100 (L100) diet 30 days. results showed that L100 control had greater average daily gain gain-to-feed ratio than L50...
Maternal gut microflora changes dramatically during perinatal period and plays a vital role in animal health reproductive performance. However, little is known about the microbial differences between sows with different productive capacities period. Hence, this study explored fecal diversity, composition, metabolic functions, phenotypes high capacity (HPC, litter size ≥ 15) low (LPC, ≤ 7) late pregnancy (LP, third day before due date) early stage after parturition (EAP, parturition) as well...
Ethanolamine (Etn) contained in milk is the base constituent of phosphatidylethanolamine and required for proliferation intestinal epithelial cells bacteria, which important maintenance gut microbiome development. The present study investigated effect Etn on function using 21-d-old Sprague-Dawley rats treated with 0, 250, 500 1000 μm drinking water 2 weeks immediately after weaning. Growth performance, morphology, antioxidant capacity mucosal immunity, as well microbiota community...
The aim of current study was to determine variations in sow's gut microbiota, serum immunity, and milk metabolite profile mediated by lysozyme supplementation. Twenty-four pregnant sows were assigned a control group without supplementation two treatments with 0.5 kg/t 1.0 provided formula feed for 21 days (n = 8 per treatment). Microbiota analysis metagenomic predictions based on 16s RNA high-throughput sequencing. Milk metabolome assessed untargeted liquid chromatography tandem mass...
Abstract Folate is increasingly thought to promote gastrointestinal health and regulate the diversity of gut microbiota alleviate weaning stress in piglets. The present study was conducted investigate effects folate on organ weight, digesta pH, short-chain fatty acids (SCFAs) concentration, intestinal weaned A total 28 piglets (6.73 ± 0.62 kg) were allocated four dietary treatments consisting a control group, 3, 9, 18 mg/kg supplementation 14-d feeding trial. results showed that fed with 9...
Abstract Magnetic resonance arthrography, a procedure where contrast agents containing gadolinium are administered intra‐articularly, has become useful tool in musculoskeletal diagnosis. Although considered safe for systemic use, toxicities some tissues have been identified both free ion and the chelates used as contrast. In this study, effects of short‐term exposure articular chondrocytes to were examined by assaying proteoglycan synthesis, cell proliferation, apoptosis. Bovine grown...
Beta-glucan has been shown to have a beneficial effect on gastrointestinal health. This experiment was conducted investigate the effects of β-glucan isolated from Agrobacterium sp. ZX09 growth performance and intestinal health weaning pigs. A total 108 weaned pigs (21 d age; 6.05 ± 0.36 kg) were randomly divided into 3 groups (6 pens/group; 6 pigs/pen), each treated with following diets: 1) basal diet, 2) diet supplemented 20 mg/kg olaquindox, 3) 200 β-glucan, for 21 d. Compared control...
1 alpha, 25-Dihydroxyvitamin D3 [1 25-(OH)2D3], the hormonal form of vitamin D3, is further metabolized in kidney and intestine through carbon 24 (C-24) oxidation pathway initiated by C-24 hydroxylation, 23 (C-23) C-23 hydroxylation. The leading to formation calcitroic acid has been previously reported be present bone cells, but 25-(OH)2D3-26,23-lactone not described even though noted have a significant effect on formation. Therefore, study, we investigated production normal human...
Hydroquinone (HQ) is widely used in food stuffs and an occupational environmental pollutant. Although the hepatotoxicity of HQ has been demonstrated both vitro vivo, prevention HQ‐induced yet to be elucidated. In this study, we focused on intervention effect aqueous extracts Flos lonicerae Japonicae (FLJ) cytotoxicity. We that reduced cell viability a concentration‐dependent manner by administering 160 μ mol/L for 12 h as positive control The FLJ significantly increased decreased LDH...
The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase family. Their functions in regulating animal development have been well studied both invertebrates and vertebrates. However, it remains to be determined whether they play a role sex determination. Here we present first evidence show that expression JNK1 displays distinct patterns during reversal rice-field eel. Molecular cloning reveals is conserved among eel other Both quantitative real-time polymerase...
Co–B amorphous alloy nanowires exhibited the improvement of catalytic hydrogenation activity and cycling life by plasma treatment.
黄酮类化合物是膳食非营养生物活性物质,广泛存在于各种植物中,具有抗氧化、抗菌和抗炎等特性。断奶应激引发的肠黏膜损伤是制约仔猪生长的关键因素。作为无污染、无残留、抗药性低的抗生素替代物之一,黄酮类化合物在提高断奶仔猪生产性能和改善肠黏膜屏障功能方面具有广泛的应用价值。本文结合本研究组关于断奶仔猪肠上皮细胞更新的相关研究成果,综述了黄酮类化合物调控肠上皮细胞更新,肠黏膜屏障损伤修复和肠道菌群平衡的药理作用及分子机制的最新研究进展,旨在为开发和应用不同种类的天然植物源黄酮类化合物作为改善断奶仔猪肠道功能的饲料添加剂提供理论依据和实践参考。