A5100376400- Sperm and Testicular Function
- Selenium in Biological Systems
- Adipose Tissue and Metabolism
- Dietary Effects on Health
- Antioxidant Activity and Oxidative Stress
- Urinary Bladder and Prostate Research
- Gynecological conditions and treatments
- Ovarian cancer diagnosis and treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Adipokines, Inflammation, and Metabolic Diseases
- Regulation of Appetite and Obesity
- Endometriosis Research and Treatment
- Neurobiology and Insect Physiology Research
- Neurological Disease Mechanisms and Treatments
- Recycled Aggregate Concrete Performance
- Cancer Risks and Factors
- Parkinson's Disease Mechanisms and Treatments
- Ginseng Biological Effects and Applications
- Microplastics and Plastic Pollution
- Telomeres, Telomerase, and Senescence
- Menstrual Health and Disorders
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Multiple and Secondary Primary Cancers
- Trace Elements in Health
Shandong Jianzhu University
2024
Huazhong University of Science and Technology
2024
Tongji Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2023
Huazhong Agricultural University
2023
Wuhan University
2023
Renmin Hospital of Wuhan University
2023
Hunan Normal University
2023
Guhua Hospital
2022
Shandong Agricultural University
2022
Obesity is a major health issue. started from teenagers has become concern in recent years. Intermittent fasting increases the life span. However, it not known whether obesity and intermittent affect brain functions structures before aging. Here, we subjected 7-week old CD-1 wild type male mice to (alternate-day) or high fat diet (45% caloric supplied by fat) for 11 months. Mice on had better learning memory assessed Barnes maze fear conditioning, thicker CA1 pyramidal cell layer, higher...
Ovarian cancer (OC) is one of the major diseases threatening women's health and life. Estimating burden trends risk factors OC can help develop effective management prevention measures. However, there a lack comprehensive analysis concerning in China. In this study, we aimed to assess predict China from 1990 2030, make comparison with global level.We extracted prevalence, incidence, mortality, disability-adjusted life years (DALYs), lost (YLLs), lived disability (YLDs) data Global Burden...
Selenium (Se), a well-known antioxidant, is important for male fertility and sperm quality. The gut microbiota involved in vital activities cross-talk between reproduction the axis. It still unclear whether mediates impact of selenium on semen quality, what underlying mechanisms may be. A selenized glucose (SeGlu) derivative novel organic Se compound. After 7 days acclimation, Sprague-Dawley (SD) rats (230 g, 6 weeks) were divided into three drinking groups: deionized water group (CK), SeGlu...
Objective: Diminished ovarian reserve (DOR) is a disorder characterized by impaired function. Sleep disorders are disruptions of the circadian rhythm, which appears to be closely linked reproductive systems. This study aimed investigate impact poor sleep quality on childbearing-age women. Methods: A cross-sectional was conducted in China from June 2021 March 2023. In total, 102 participants diagnosed with chronic insomnia were included study. Questionnaires administered assess participants'...
Endometriosis is a common nonfatal gynecological disease, and infertility one of its main dangers. Endometriosis-related causes serious damage to women's health places burden on women reproductive age. The aim this study was describe the current endometriosis-associated analyze spatiotemporal trends.Age-standardized prevalence rate (ASPR) data from 1990 2019 for primary (ERPI) secondary (ERSI) were obtained Global Burden Disease Study (GBD) 2019. These spanning three decades cover global,...
Selenium (Se), an essential trace element for human health, mainly exerts its biological function via selenoproteins. Among the 25 selenoproteins identified in human, selenoprotein P (SelP) is only one that contains multiple selenocysteines (Sec) sequence, and has been suggested to as a Se transporter. Upon feeding selenium-deficient diet, mice lacking SelP develop severe neurological dysfunction exhibit widespread brainstem neurodegeneration, indicating important role of normal brain...
To uncover the molecular mechanism underlying glucocorticoid-induced loss of mitochondrial integrity in skeletal muscles, studies were performed to investigate whether peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1)-mediated pathway was involved this process. In an vivo trial, 3 groups 30-d-old Arbor Acres male broilers randomly subjected one following treatments for 7 days: corticosterone (CORT, 30 mg/kg diet), control (blank), and pair-feeding (restricted same feed...
Nelumbo nucifera Gaertn. is an important aquatic vegetable, and its dried stamen (Nelumbinis stamen, NS) a valuable nutraceutical usually used as herbal tea. Here, we ultrahigh-performance liquid chromatography (UPLC)–quadrupole time-of-flight mass spectrometry high-performance (HPLC) to chemically profile NS quantify their main constituent flavonoids, respectively. In total, 44 components were identified, including organic acids, monoterpene glycosides, fatty acids. Experimental mice...
Limonin is a tetracyclic triterpenoid compound enriched in citrus fruits. Whether it effective against obesity and the underlying molecular mechanisms remain unknown. Herein, high-fat diet (HFD) was given to male C57BL/6J mice for four weeks induce obesity. After that, limonin (50 mg/kg) orally administered another 8 along with HFD. treatment remarkably decreased fat mass body weight gain, simultaneously alleviated HFD-induced fatty liver hyperlipidemia. prevented whitening of brown adipose...
Ginkgolide B (GKB) is a well-established neuroprotectant for acute ischemia stroke. However, its cerebral exposure and real-time response remain elusive in ischemia/reperfusion stage, it hinders usage therapeutic window of Therefore, we investigate the exposure-response relationship GKB (10 mg/kg, intravenously (i.v.)) as well neuroprotective mechanism rats. Cerebral plasma comparatively explored both normal rats Correspondingly, neurological function brain jury indexes were assessed at each...
A large number of long non-coding RNAs are expressed in animal gonads, but their functions poorly understood. In this study, a gonad-specific lncRNA, termed lnc4, was identified and characterised the model medaka (Oryzias latipes), which consists two exons with mature RNA length 3215 nt. males, lnc4 predominantly all germ cells testis. Deletion locus led to significant reduction testis size dramatic decrease male cells, as well sperm viability. Second, knockout resulted enhanced synthesis...