Aaron Ferron
A5017740233- CRISPR and Genetic Engineering
- Autophagy in Disease and Therapy
- Adenosine and Purinergic Signaling
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- COVID-19 epidemiological studies
- Family and Patient Care in Intensive Care Units
- Infection Control and Ventilation
- RNA Research and Splicing
- Geriatric Care and Nursing Homes
- RNA and protein synthesis mechanisms
- Biosensors and Analytical Detection
- HIV Research and Treatment
- Intensive Care Unit Cognitive Disorders
The Francis Crick Institute
2018-2021
University College London
2020
University College London Hospitals NHS Foundation Trust
2020
National Hospital for Neurology and Neurosurgery
2020
The retroviral restriction factor tripartite motif–containing 5α (Trim5α) acts during the early postentry stages of life cycle to block infection by a broad range retroviruses, disrupting reverse transcription and integration. mechanism this is poorly understood, but it has recently been suggested involve recruitment components autophagy machinery, including members mammalian autophagy-related 8 (ATG8) family involved in targeting proteins autophagosome. To better understand molecular...
Abstract The genomes of inbred mice harbor around 50 endogenous murine leukemia virus (MLV) loci, although the specific complement varies greatly between strains. Gv1 locus is known to control transcription MLVs and be dominant determinant cell-surface presentation MLV envelope, GIX antigen. Here, we identify a single Krüppel-associated box zinc finger protein (ZFP) gene, Zfp998, as show it necessary sufficient determine GIX+ phenotype. By long-read sequencing bacterial artificial chromosome...