A5100410128- Genetic Mapping and Diversity in Plants and Animals
- Genetic and phenotypic traits in livestock
- Cancer-related molecular mechanisms research
- Immune Response and Inflammation
- Milk Quality and Mastitis in Dairy Cows
- Muscle metabolism and nutrition
- Reproductive Physiology in Livestock
- Genetics and Physical Performance
- Advances in Cucurbitaceae Research
- Animal Disease Management and Epidemiology
- Viral gastroenteritis research and epidemiology
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- RNA modifications and cancer
- Probiotics and Fermented Foods
- Wheat and Barley Genetics and Pathology
- Bioenergy crop production and management
- Vector-Borne Animal Diseases
- Cancer, Hypoxia, and Metabolism
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Antimicrobial Peptides and Activities
- Advanced Photocatalysis Techniques
- High Altitude and Hypoxia
- Oral microbiology and periodontitis research
- MicroRNA in disease regulation
- Asthma and respiratory diseases
Yangzhou University
2007-2025
Shanghai University of Traditional Chinese Medicine
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024
Tiangong University
2024
Institute of Microbiology
2022-2023
Shanghai Veterinary Research Institute
2023
Peking Union Medical College Hospital
2023
South China Agricultural University
2023
Sichuan University
2021-2022
West China Hospital of Sichuan University
2021-2022
The productivity of sorghum is mainly determined by agronomically important traits. genetic bases these traits have historically been dissected and analysed through quantitative trait locus (QTL) mapping based on linkage maps with low-throughput molecular markers, which one the factors that hinder precise complete information about numbers locations genes or QTLs controlling In this study, an ultra-high-density map high-quality single nucleotide polymorphisms (SNPs) generated from...
Given the low resection rate and chemoresistance of patients with pancreatic cancer (PC), their survival rates are typically poor. Long noncoding RNAs (lncRNAs) have recently been shown to play an important role in tumourigenesis human progression, including PC. In this study, we aimed investigate taurine-upregulated gene 1 (TUG1) A quantitative polymerase chain reaction was used analyse TUG1 expression PC tissues peritumoural normal tissues. overexpressed compared that tissues, high...
Steroidogenic factor 1 (SF1) is a member of the NR5A subfamily nuclear hormone receptors and considered master regulator reproduction because it regulates number genes encoding reproductive hormones enzymes involved in steroid biosynthesis. Like other members, SF1 harbors highly conserved approximately 30-residue segment called FTZ-F1 box C-terminal to core DNA binding domain (DBD) common all binds 9-bp sequences as monomer. Here we describe solution structure DBD complex with an atypical...
Reproduction is an important production activity for dairy cows, and their reproductive performance can directly affect the level of farmers’ income. To better understand genomic regions biological pathways reproduction-related traits in present study, three body shape traits—Loin Strength (LS), Rump Angle (RA), Pin Width (PW)—were selected as indicators ability we conducted genome-wide association analyses on them. The heritability these was medium, ranging from 0.20 to 0.38. A total 11...
Abstract Low‐coverage whole genome sequencing (lcWGS) has great potential to effectively genotype large‐scale population and provide solid data for imputation; however, the time imputation needs be optimized. There is also no publicly available reference panel selection in cattle. Here, we proposed a combination of Beagle v5.4 phasing GLIMPSE2 imputation, which fast accurate cattle lcWGS data. Furthermore, established multi‐breed with 61.8 million SNPs based on 2976 worldwide cattle, 1766...
Grain size is a major determinant of grain yield in sorghum and other cereals. Over 100 quantitative trait loci (QTLs) have been identified sorghum. However, no gene underlying any QTL has cloned. Here, we describe the fine mapping cloning one QTL. From an F8 recombinant inbred line population derived from cross between lines 654 LTR108, 44 QTLs. One QTL, qTGW1a, was detected consistently on long arm chromosome 1 span 4 years. Using extreme recombinants F2:3 fine-mapping population, qTGW1a...
Accurately estimating the genetic parameters and revealing more variants underlying milk production quality are conducive to improvement of dairy cows. In this study, we estimate five milk-related traits cows-namely, yield (MY), fat percentage (MFP), (MFY), protein (MPP), (MPY)-based on a random regression test-day model. A total 95,375 records 9,834 cows in lower reaches Yangtze River were used for estimation. addition, genome-wide association studies (GWASs) these conducted, based adjusted...
The hypothalamic-pituitary-thyroid (HPT) axis hormones regulate the growth and development of ruminants, pituitary gland plays a decisive role in this process. In order to identify pivotal genes that could affect cattle by regulating secretion hormones, we detected content six HPT related plasma two breeds (Yunling Leiqiong cattle, both also known as zebu cattle) with great differences compared transcriptome data their glands. Our study found contents GH, IGF, TSH, thyroxine,...
The objective of this study was to explore the effect dam body conformations on birth traits including stillbirth, dystocia, gestation length and weight Chinese Holstein calves provide a reference for improving cow reproductive performance. We collected phenotype data 20 conformation cows analyzed impact trait linear scores calf weight. feet angle, set rear legs, fore udder attachment height dairy significantly affected risk stillbirth. dystocia decreases with increase in stature pin width....
ABSTRACT Traditional vaccine efficacy evaluation predominantly relies on antibody levels, while the assessment of T-cell responses remains underexplored. In this study, we employed multi-parameter flow cytometry to comprehensively analyze in cows vaccinated against foot-and-mouth disease (FMD). We categorized into high and low potency groups based levels investigated differences between these groups. Phenotypic analysis revealed a significant reduction CD4, CD8, γδ T cells peripheral blood...
This study examined the effects of long non‑coding RNA (lncRNA) BC032020 on development human pancreatic ductal adenocarcinoma (PDAC), and potential molecular mechanisms responsible for these effects. The expression was assessed in 20 pairs PDAC tumor tissues adjacent normal tissues. overexpression enforced AsPC‑1 PANC‑1 cells, cell proliferation, cycle distribution, migration apoptosis were determined. We also analyzed functions zinc finger protein 451 (ZNF451), which shares a gene sequence...
The Mongolian horses have excellent endurance and stress resistance to adapt the cold harsh plateau conditions. Intraspecific genetic diversity is mainly embodied in various advantages of different branches horse. Since people pay progressive attention athletic performance horse, we expect guide exercise-oriented breeding through genomics research. We obtained clean data 630,535,376,400 bp entire genome second-generation sequencing for whole blood four Abaga ten Wushen horses. Based on...
Abstract Sorghum has high salt tolerance, and the localization discovery of tolerance regulatory genes in sorghum is an effective way to develop utilize saline soils. The aim this study was locate using a F 2 segregating population combined with bulked segregation analysis (BSA) sequencing technology explore potential sorghum. results showed that data percentage all four samples (salt‐tolerant parent, salt‐tolerant offspring pool, salt‐sensitive parent pool) above 99.90%. By comparing each...