Marije B. Hoos
A5007089439- Obesity, Physical Activity, Diet
- Clinical Nutrition and Gastroenterology
- Body Composition Measurement Techniques
- Cardiomyopathy and Myosin Studies
- Metabolism and Genetic Disorders
- Behavioral Health and Interventions
- Diet and metabolism studies
- Nutritional Studies and Diet
- Thermoregulation and physiological responses
- Evolutionary Psychology and Human Behavior
- Children's Physical and Motor Development
- Nutrition and Health in Aging
- Physical Activity and Health
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Effects of Exercise
- Growth Hormone and Insulin-like Growth Factors
- Ion channel regulation and function
- Climate Change and Health Impacts
- Electrolyte and hormonal disorders
- Renal function and acid-base balance
- Environmental Impact and Sustainability
- Animal Behavior and Reproduction
- Spaceflight effects on biology
- Lipid metabolism and disorders
- Eating Disorders and Behaviors
Maastricht University Medical Centre
1999-2025
Maastricht University
2003-2022
Netherlands Heart Institute
2018
Nederlandse Vereniging voor Kindergeneeskunde
2003
Royal Netherlands Academy of Arts and Sciences
2003
Understanding the impacts of activity on energy balance is crucial. Increasing levels may bring diminishing returns in expenditure because compensatory responses non-activity expenditures.1Pontzer H. Durazo-Arvizu R. Dugas L.R. Plange-Rhule J. Bovet P. Forrester T.E. Lambert E.V. Cooper R.S. Schoeller D.A. Luke A. Constrained total and metabolic adaptation to physical adult humans.Curr. Biol. 2016; 26: 410-417Abstract Full Text PDF PubMed Scopus (145) Google Scholar, 2Halsey L.G. The mystery...
The doubly labeled water (DLW) method measures total energy expenditure (TEE) in free-living subjects. Several equations are used to convert isotopic data into TEE. Using the International Atomic Energy Agency (IAEA) DLW database (5,756 measurements of adults and children), we show considerable variability is introduced by different equations. estimated rCO2 sensitive dilution space ratio (DSR) two isotopes. Based on performance validation studies, propose a new equation based estimate mean...
Water is essential for survival, but one in three individuals worldwide (2.2 billion people) lacks access to safe drinking water. intake requirements largely reflect water turnover (WT), the used by body each day. We investigated determinants of human WT 5604 people from ages 8 days 96 years 23 countries using isotope-tracking (
Abstract Nutritional epidemiology aims to link dietary exposures chronic disease, but the instruments for evaluating intake are inaccurate. One way identify unreliable data and sources of errors is compare estimated intakes with total energy expenditure (TEE). In this study, we used International Atomic Energy Agency Doubly Labeled Water Database derive a predictive equation TEE using 6,497 measures in individuals aged 4 96 years. The resultant regression predicts expected from easily...
Phenotypic heterogeneity and incomplete penetrance are common in patients with hypertrophic cardiomyopathy (HCM). We aim to improve the understanding genotype–phenotype correlations HCM, particularly contribution of an MYL2 founder mutation risk factors left ventricular remodelling. analysed 14 HCM families whom 38 family members share c.64G > A [p.(Glu22Lys)] a haplotype. In this unique cohort, we investigated influencing phenotypic outcome addition primary mutation. The alone showed benign...
Physical activity may be a way to increase and maintain fat-free mass (FFM) in later life, similar the prevention of fractures by increasing peak bone mass.
In mammals, trait variation is often reported to be greater among males than females. However, date, mainly only morphological traits have been studied. Energy expenditure represents the metabolic costs of multiple physical, physiological, and behavioral traits. could exhibit particularly high male through a cumulative effect if those mostly variation, or lack many them do not. Sex differences in energy little explored. We analyzed large database on adult humans (1494 3108 females)...
Abstract Low total energy expenditure (TEE, MJ/d) has been a hypothesized risk factor for weight gain, but repeatability of TEE, critical variable in longitudinal studies balance, is understudied. We examine repeated doubly labeled water (DLW) measurements TEE 348 adults and 47 children from the IAEA DLW Database (mean ± SD time interval: 1.9 2.9 y) to assess if adjusted age, sex, fat-free mass, fat mass associated with changes or body composition. Here, we report that high adults, not...
Background: Genetic evaluation is recommended in patients with unexplained dilated cardiomyopathy (DCM), but its diagnostic yield and prognostic relevance isolated left ventricular dysfunction (LVdys) unknown. Methods Results: A total of 127 LVdys 262 DCM underwent genetic screening. Long-term outcome consisted a combined end point life-threatening arrhythmia, heart transplantation, death. At baseline, were younger had less frequently New York Heart Association class ≥3 when compared (55±13...
Lower ambient temperature (T
The objective of this study was to investigate whether short-term changes in metabolism, as a result GH therapy, could be used predict its growth effect after 1 yr. Twenty-eight children (8.7 +/- 2.8 yr) were selected, based on anthropometric criteria characterizing GH-deficient patients. In addition, 21 healthy, age- and sex-matched controls (8.9 3.1 included. Total body water (TBW) height measured before at 6 wk yr the start treatment. After treatment, patients divided into good poor...
There is considerably greater variation in metabolic rates between men than women, terms of basal, activity and total (daily) energy expenditure (EE). One possible explanation that EE associated with male sexual characteristics (which are known to vary more other traits) such as musculature athletic capacity. Such traits might be predicted most prominent during periods adolescence young adulthood, when behaviour develops peaks. We tested this hypothesis on a large dataset by comparing the...
39 Introduction: Protein metabolism in critical illness is characterized by degradation of muscle proteins and negative nitrogen balance. The "[15N]-glycine single oral dose method" a well described method to evaluate whole body protein non invasive manner. Reported results with this are good agreement those obtained "precursor" methods. In children, however, only few studies making use the [15N]-glycine have been reported. Aims: Evaluation "[15N]glycine critically ill children healthy...