Gong Chen

ORCID: 0000-0002-5835-3605
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Viral Infections and Vectors
  • Colorectal Cancer Treatments and Studies
  • Gut microbiota and health
  • Pediatric Hepatobiliary Diseases and Treatments
  • Hydrology and Drought Analysis
  • Probiotics and Fermented Foods
  • Infant Nutrition and Health
  • Respiratory and Cough-Related Research
  • Mosquito-borne diseases and control
  • Pancreatitis Pathology and Treatment
  • Cancer Treatment and Pharmacology
  • Intestinal Malrotation and Obstruction Disorders
  • Pediatric health and respiratory diseases
  • Cardiac pacing and defibrillation studies
  • Microbial Metabolism and Applications
  • Reservoir Engineering and Simulation Methods
  • Fermentation and Sensory Analysis
  • Genetic factors in colorectal cancer
  • Inflammatory Bowel Disease
  • Immune Response and Inflammation
  • Facial Rejuvenation and Surgery Techniques
  • Autopsy Techniques and Outcomes
  • Kruppel-like factors research
  • Membrane Separation and Gas Transport
  • Tannin, Tannase and Anticancer Activities

Anhui Medical University
2021-2025

Second Hospital of Anhui Medical University
2021-2025

Peking University Third Hospital
2020-2024

Peking University
2008-2024

Children's Hospital of Fudan University
2024

Merchants Chongqing Communications Research and Design Institute
2024

First Affiliated Hospital of Anhui Medical University
2022-2024

Northern Jiangsu People's Hospital
2024

Ministry of Education of the People's Republic of China
2024

Sun Yat-sen University
2010-2023

ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease caused by a novel bunyavirus that poses significant threat to human health. The aim of this study was identify precise and user‐friendly indicator for predicting the mortality patients SFTS. We retrospectively analyzed data from 181 hospitalized Inflammatory markers, including neutrophil‐to‐lymphocyte ratio (NLR), lymphocyte‐to‐monocyte (LMR), platelet‐to‐lymphocyte (PLR), systemic inflammation index (SII),...

10.1002/jmv.70225 article EN Journal of Medical Virology 2025-02-01

This study assessed whether antibiotics could alter gut microbiota to affect host growth and the possibility of alleviation by lactobacilli. We divided four-week-old BABL/c mice into control (Ctrl), antibiotic exposure (Abx), Lactobacillus plantarum PC-170 (PC), rhamnosus GG (LGG) group Abx, LGG, PC received an one-week antibiotic/antibiotic + probiotic treatment. The fecal expression splenic cytokines were determined. Following ceftriaxone treatment, body weight gain Abx was delayed...

10.1080/09168451.2019.1676696 article EN Bioscience Biotechnology and Biochemistry 2019-10-29

Recurrent pregnancy loss is a distressing event during pregnancy, and understanding its causal factors crucial. Follistatin, glycoprotein involved in folliculogenesis embryogenesis, has been implicated as potential contributor to the risk of spontaneous abortion. However, establishing relationship requires rigorous investigation using robust methods. In this study, we utilized mendelian randomization (MR), powerful genetic epidemiological approach, examine between follistatin levels We...

10.3389/fendo.2023.1255591 article EN cc-by Frontiers in Endocrinology 2024-01-03

Abstract Severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease a high fatality rate. Cardiac injury in SFTS patients is major concern. This study aimed to evaluate the prevalence of cardiac and its association mortality hospitalized infected novel Bunyavirus. was defined as presence any following abnormalities: (1) blood levels biomarkers (creatine kinase‐MB, troponin‐I, B‐type natriuretic peptide or N‐terminal pro‐B‐type peptide); (2) new abnormalities...

10.1002/jmv.29375 article EN Journal of Medical Virology 2024-01-01

BACKGROUND:This study aimed to investigate the effects on gut microbiome of 40 infants delivered before term by cesarean section between antibiotic treatment and probiotics as assessed 16S rRNA quantitative polymerase chain reaction (qPCR) sequencing. MATERIAL AND METHODS:We divided premature into 4 groups according exposure antibiotics or probiotics: N group (No-probiotics No-antibiotics), A (antibiotics), P (probiotics), AP (antibiotics+probiotics). Fecal samples were collected days 1, 3,...

10.12659/msm.928467 article EN Medical Science Monitor 2021-02-05

Guava leaves are used in traditional herbal teas as antidiabetic therapies. Flavonoids the main active of and have many physiological functions. However, flavonoid compositions activities could change due to microbial fermentation. A high-performance liquid chromatography time-of-flight electrospray ionization mass spectrometry method was applied identify varieties flavonoids before after High-performance chromatography, hierarchical cluster analysis principal component were quantitatively...

10.1002/jssc.201600552 article EN Journal of Separation Science 2016-08-29

This study aims to evaluate the predictive role of age-adjusted Charlson comorbidity index (ACCI) scores for in-hospital prognosis severe fever in thrombocytopenia syndrome (SFTS) patients. A total 192 patients diagnosed with SFTS were selected as subjects. Clinical data retrospectively collected. Receiver operating characteristic curves used diagnostic value ACCI mortality patients, and Cox regression models assess association between factors prognosis. The divided into two groups according...

10.1017/s0950268823001930 article EN cc-by-nc-nd Epidemiology and Infection 2023-01-01

Abstract Previous studies have suggested that deficiencies in mismatch repair genes ( dMMR ) often occur patients with colorectal cancer CRC and contribute to disease etiology. Here, we looked for a correlation of MMR status outcomes from large number Chinese stratified by the age onset disease. A total 2233 were analyzed tissue biopsies surgically removed tumors scored gene status. The patient distribution after classification consisted 188 younger aged (20–39 years age), 1024 middle (40–59...

10.1002/cam4.1007 article EN cc-by Cancer Medicine 2017-03-27

AIM:To determine the accuracy of p53 gene mutations predicted by overexpression protein immunohistochemically, and to investigate co-mutation K-ras genes in rectal cancer its effect on promoting malignant biologic behaviors tumors. METHODS:Ninety-seven specimens were surgically resected our hospital from August 1996 October 1997.The hot mutation areas (in exons 5-8) codon 5/12 13) detected with polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP), was...

10.3748/wjg.v10.i24.3688 article EN cc-by-nc World Journal of Gastroenterology 2004-01-01

10.1016/s1872-2040(19)61203-x article EN CHINESE JOURNAL OF ANALYTICAL CHEMISTRY (CHINESE VERSION) 2019-12-01

Untreated protracted bacterial bronchitis (PBB), a chronic wet cough prevalent in children, may lead to suppurative lung disease. However, clinical diagnostic criteria are currently nonspecific; thus, PBB be misdiagnosed. Thus, we assessed the value of fiberoptic bronchoscopy (FOB) and risk factors associated with PBB.Children at The First Affiliated Hospital Anhui Medical University from January 2015 May 2020 were enrolled allocated suspected (n = 141) or non-PBB 206) group. All children...

10.1155/2023/8116651 article EN cc-by International Journal of Clinical Practice 2023-07-05

Progressive hemifacial atrophy (PHA) is a nonnegligible disease, and its treatment currently lacks consensus. We aim to conduct an analysis of PHA patients summarize the postoperative effect. Moreover, we introduced free serratus anterior muscle-fascial composite tissue flap as safe novelty surgical procedure for moderate-severe PHA. This clinical study included four who received 19 Coleman fat transplantation. Preoperative (preoperative photograph imageological examination) (postoperative...

10.1016/j.asjsur.2023.11.044 article EN cc-by-nc-nd Asian Journal of Surgery 2023-11-30

Abstract Poly(ether ether ketone) (PEEK) hollow fiber membranes were prepared by a thermally induced phase separation method with polyetherimide as diluent, and N ‐methyl pyrrolidone (NMP), dichloromethane composite extractant composed of NMP, ethanolamine water extractant. The effects the different solvents crystallization on pore structure during extraction properties PEEK investigated in detail. behaviors characterized DSC XRD. effect extractants microscopic morphologies, structures,...

10.1002/pi.5897 article EN Polymer International 2019-08-02

In this study, Monascus pigments were separated from the extractive fermentation broth by combination of reverse micellar extraction and macroporous resins (MACR) adsorption with alkalizing S-8 MACR (S-8 ALR). A 95.07% pigment was achieved together a relative low Triton X-100 co-adsorption that only 2.53%. The liquid intraparticle diffusion film limit rate. 79.48–84.03% could be eluted resin using methanol solution containing 0.5% (w/v) hydrochloric acid. ALR recovered for cycle use without...

10.1080/01496395.2018.1461906 article EN Separation Science and Technology 2018-04-24

Purpose Existing studies mostly rely on the static characteristics of team members, and there is still a lack empirical investigation how entrepreneurial members make decisions through dynamic process members’ cognition influences decision-making. The purpose this study to validate heterogeneity affects decision-making performance from perspective process. Design/methodology/approach Drawing theory input-process-output model, proposed examined mediating role interaction as well moderating...

10.1108/cms-12-2020-0564 article EN Chinese Management Studies 2021-08-26
Coming Soon ...