A5103060034- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Circular RNAs in diseases
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Hydrology and Drought Analysis
- Cardiac Ischemia and Reperfusion
- Cardiac Fibrosis and Remodeling
- Galectins and Cancer Biology
- Inflammasome and immune disorders
- Gut microbiota and health
- Fatty Acid Research and Health
- Cardiovascular Function and Risk Factors
- Pregnancy-related medical research
- Climate Change and Health Impacts
- Pulmonary Hypertension Research and Treatments
- Neonatal and Maternal Infections
- Neonatal Respiratory Health Research
- Botulinum Toxin and Related Neurological Disorders
- Cardiovascular Effects of Exercise
- Vector-Borne Animal Diseases
- Precipitation Measurement and Analysis
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Eicosanoids and Hypertension Pharmacology
- Respiratory Support and Mechanisms
- Infant Nutrition and Health
University of Science and Technology of China
2021-2025
Chinese Academy of Sciences
2024
First Affiliated Hospital of Henan University of Science and Technology
2023
Second Hospital of Anhui Medical University
2021
Anhui Medical University
2021
Acute lung injury (ALI) is characterized by pulmonary diffusion abnormalities that may progress to multiple-organ failure in severe cases. There are limited effective treatments for ALI, which makes the search new therapeutic avenues critically important. Macrophages play a pivotal role pathogenesis of ALI. The degree macrophage polarization closely related severity and prognosis S100A9 promotes M1 macrophages. present study assessed effects S100A9-gene deficiency on acute injury. Our cohort...
ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease caused by a novel bunyavirus that poses significant threat to human health. The aim of this study was identify precise and user‐friendly indicator for predicting the mortality patients SFTS. We retrospectively analyzed data from 181 hospitalized Inflammatory markers, including neutrophil‐to‐lymphocyte ratio (NLR), lymphocyte‐to‐monocyte (LMR), platelet‐to‐lymphocyte (PLR), systemic inflammation index (SII),...
Abstract Severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease a high fatality rate. Cardiac injury in SFTS patients is major concern. This study aimed to evaluate the prevalence of cardiac and its association mortality hospitalized infected novel Bunyavirus. was defined as presence any following abnormalities: (1) blood levels biomarkers (creatine kinase‐MB, troponin‐I, B‐type natriuretic peptide or N‐terminal pro‐B‐type peptide); (2) new abnormalities...
BACKGROUND:This study aimed to investigate the effects on gut microbiome of 40 infants delivered before term by cesarean section between antibiotic treatment and probiotics as assessed 16S rRNA quantitative polymerase chain reaction (qPCR) sequencing. MATERIAL AND METHODS:We divided premature into 4 groups according exposure antibiotics or probiotics: N group (No-probiotics No-antibiotics), A (antibiotics), P (probiotics), AP (antibiotics+probiotics). Fecal samples were collected days 1, 3,...
This study aims to evaluate the predictive role of age-adjusted Charlson comorbidity index (ACCI) scores for in-hospital prognosis severe fever in thrombocytopenia syndrome (SFTS) patients. A total 192 patients diagnosed with SFTS were selected as subjects. Clinical data retrospectively collected. Receiver operating characteristic curves used diagnostic value ACCI mortality patients, and Cox regression models assess association between factors prognosis. The divided into two groups according...
Progressive hemifacial atrophy (PHA) is a nonnegligible disease, and its treatment currently lacks consensus. We aim to conduct an analysis of PHA patients summarize the postoperative effect. Moreover, we introduced free serratus anterior muscle-fascial composite tissue flap as safe novelty surgical procedure for moderate-severe PHA. This clinical study included four who received 19 Coleman fat transplantation. Preoperative (preoperative photograph imageological examination) (postoperative...
Coronary artery calcification (CAC) is a hallmark event in the pathogenesis of cardiovascular disease, involving phenotypic transformation vascular smooth muscle cells (VSMC) towards an osteogenic state. Despite this understanding, molecular mechanisms governing VSMC switch remain incompletely elucidated. Here, we sought to examine potential role circular RNA (circRNA) context CAC. Through transcriptome analysis circRNA-seq, identified circTOP1 as candidate circRNA individuals with...
Abstract The present study was designed to investigate whether 17β-estrogen (E2) reduces myocardial I/R injury by inhibiting NLRP3 inflammasome mediated pyroptosis. In vivo , four-weeks-old female C57BL/6 mice underwent ovariectomy (Ovx) before E2 replacement therapy. After the establishment of injury, plasma E2, LDH and CK-MB were detected, infarction (MI) size, TUNEL immunofluorescence, expressions TXNIP, NLRP3, caspase-1, apoptosis-associated speck-like protein containing a CARD (ASC),...