A5033026314- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
- Cardiac Structural Anomalies and Repair
- Congenital Heart Disease Studies
- Cardiac Ischemia and Reperfusion
- Organ and Tissue Transplantation Research
- Congenital heart defects research
- Mechanical Circulatory Support Devices
- Renal Transplantation Outcomes and Treatments
- Transplantation: Methods and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Cytomegalovirus and herpesvirus research
- Cardiac Fibrosis and Remodeling
- Tissue Engineering and Regenerative Medicine
- Intracranial Aneurysms: Treatment and Complications
- Renal Diseases and Glomerulopathies
- Cardiac, Anesthesia and Surgical Outcomes
- Vasculitis and related conditions
- Central Venous Catheters and Hemodialysis
- Blood donation and transfusion practices
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- Mitochondrial Function and Pathology
Johannes Kepler University of Linz
2024
Kepler Universitätsklinikum
2017-2024
Fistula Foundation
2020
Deutsches Herzzentrum München
2014-2016
Women's General Hospital
2015
Technical University of Munich
2015
Innsbruck Medical University
2008-2013
The heterotopic cervical heart transplantation in mice is a valuable tool transplant and cardiovascular research. cuff technique greatly simplifies this model by avoiding challenging suture anastomoses of small vessels thereby reducing warm ischemia time. In comparison to abdominal graft implantation the less invasive implanted easily accessible for further follow-up examinations. Anastomoses are performed pulling ascending aorta over with recipient's common carotid artery main pulmonary...
Double-arterial cannulation enables cerebral perfusion and lower body during aortic arch reconstruction. The aim of this study was to analyse report our experience using technique on paediatric patients.A retrospective single-centre carried out 407 consecutive patients who underwent an reconstruction under double-arterial between 2003 2015. median age the at surgery 8 (range 2-5570) days, weight 3.3 1.8-60) kg. All operations were performed through standard sternotomy. One arterial cannula...
The contribution of resident stem or progenitor cells to cardiomyocyte renewal after injury in adult mammalian hearts remains a matter considerable debate. We evaluated cell population the mouse heart induced by myocardial infarction (MI) and characterized an activated Nkx2.5 enhancer element that is specific for multipotent cardiac (CPCs) during embryonic development. hypothesized these MI-induced (MICs) harbour cardiomyogenic properties similar their counterparts.MICs reside mainly...
The impact of permanent pacemaker (PPM) leads on functional outcome tricuspid valve (TV) repair has not been clearly demonstrated. Therefore, controversy exists as to whether transvalvular PPM should be explanted and replaced by epicardial at the time repair. This study evaluates influence outcome, TV-related reoperations survival in patients undergoing TV for regurgitation (TR).We retrospectively reviewed 415 consecutive who underwent ring annuloplasty our institution from July 2007...
Risk factors for delayed graft function (DGF) in pancreas transplantation (PTx) and its implications on survival are poorly defined.Eighty-seven consecutive first-time PTx type I diabetes performed between January 2003 December 2007 were retrospectively reviewed. DGF was defined as a reversible need exogenous insulin beyond postoperative day 10 (DGF group [DGFG]). For statistical analysis, DGFG patients compared with immediate (control [CG]).DGF occurred 16 (18.6%). C-peptide levels...
We report a case of 64-year-old man who developed painful pulsatile mass in the distal forearm after bicycle fall with fracture wrist. Ultrasonography confirmed 2.5-cm large pseudoaneurysm radial artery. The patient underwent surgical exploration. was resected and defect arterial wall reconstructed an autologous saphenous vein patch. suggest that double supply hand should be preserved whenever possible.
The heterotopic cervical heart transplantation in mice is a valuable tool transplant and cardiovascular research. cuff technique greatly simplifies this model by avoiding challenging suture anastomoses of small vessels thereby reducing warm ischemia time. In comparison to abdominal graft implantation the less invasive implanted easily accessible for further follow-up examinations. Anastomoses are performed pulling ascending aorta over with recipient's common carotid artery main pulmonary...
<b><i>Background/Objective:</i></b> Calcium loading has been associated with cardiovascular risk in hemodialysis (HD) patients. However, it remains to be elucidated whether alterations of intradialytic calcium buffering add the increased disease burden this high-risk population. <b><i>Methods:</i></b> Intradialytic kinetics was evaluated a cross-sectional observational study by measuring dialysate-sided ionized mass balance...
Background Various devices have been proposed for ring annuloplasty in patients with degenerative mitral valve disease. This study reports the first time midterm results rigid three-dimensional Medtronic Profile 3D (Medtronic, Minneapolis, Minnesota, United States) ring. Methods Between June 2009 and 2011, 200 (mean age 61 ± 13 years, 70% male) severe regurgitation underwent repair using A total of 106 (53.0%) isolated 94 (47.0%) a concomitant procedure such as coronary artery bypass...
A neoaortic aneurysm after a Norwood type reconstruction of the aorta can develop due to systemic pressure on former pulmonary artery wall. complex valve sparing procedure preserve native valves and avoid replacement with requirement for anticoagulation. This operation was carried out in 3 patients, 2 them Fontan palliation, 1 Norwood-Rastelli repair. The done using Dacron prostheses dilated wall, similar Yacoub modification cases David's patient. postoperative course uneventful function...
Patients requiring coronary artery bypass grafting (CABG) and carotid endarterectomy (CEA) can be managed with staged (CEA before CABG), reverse (CABG CEA) or synchronous treatment. This single-center retrospective study evaluated the outcomes in patients undergoing planned CEA CABG. Between 2000 2020 a total of 185 symptomatic triple-vessel left main disease associated 70–99% asymptomatic 50–99% uni- bilateral internal (ICA) stenosis underwent CABG at our institution. Study endpoints were...
Objectives Although the Perceval sutureless aortic valve bioprosthesis presents a feasible alternative to conventional prostheses, extent of its applicability with respect technical considerations for real-world patient collective is still under debate. Methods One hundred patients received prosthesis [males: 59; age: 72.5 (7.3–79) years] between December 2015 and February 2023 [EuroSCORE II: 2.8 (1.7–5.4)] an replacement (AVR), additional concomitant procedures, underlying severe stenosis [...
Giant cell arteritis is an inflammatory vasculopathy of unknown etiology that typically affects the carotid artery and its branches. Symptomatic involvement upper extremity arteries uncommon. We report a case 70-year-old woman with polymyalgia rheumatica who presented critical arm ischemia, constitutional symptoms, elevated erythrocyte sedimentation rate. Urgent revascularization by carotid-brachial bypass was performed. Histopathologic evaluation specimen obtained intraoperatively from...
Background Neo-aortic root dilatation accounts for the majority of reoperations needed after Ross procedure with implantation pulmonary autograft as complete replacement. This study evaluates early results external prosthetic reinforcement autograft. Methods From July 2015 to October 2017, 16 adolescent and adult patients received a at our department by this technique. A congenital-dysplastic valve was present in 13 patients, including 9 bicuspid aortic valve. Clinical echocardiographic...
Objectives: Recent studies have demonstrated a limited capacity of the postnatal mammalian heart for endogenous regeneration. The cellular resources and mechanisms are barely understood.
Abstract Tetrahydrobiopterin (BH 4 ) and 4-amino-tetrahydrobiopterin (ABH prevent acute rejection after solid organ transplantation. Moreover, BH also attenuates ischemia-reperfusion injury (IRI). The mechanisms underlying these protective effects are poorly defined. Activation of intracellular signaling proteins, including the mitogen-activated protein kinases (MAPKs) ERK, p38, JNK, excessive production mitochondrial reactive oxygen species (ROS) observed mainly during early reperfusion....
Mark, W.; Ratschiller, T.; Öllinger, R.; Weissenbacher, A.; Schneeberger, S.; Boesmueller, C.; Pratschke, J.; Biebl, M. Author Information
Maglione, M.1; Biebl, M.2; Bonatti, H.3; Goebel, G.4; Ratschiller, T.5; Schneeberger, S.6; Brandacher, G.7; Hengster, P.4; Margreiter, C.6; Berger, N.8; Mark, W.9; Pratschke, J.6; R.9 Author Information
Sucher, R; Smigelskaite, J; Gehwolf, P; Kuznetsov, A; Hermann, M; Doblander, C; Maglione, Ratschiller, T; Brandacher, G; Margreiter, Troppmair, J Author Information