A5055094699- Cellular Mechanics and Interactions
- Cardiomyopathy and Myosin Studies
- Plant Reproductive Biology
- Multicomponent Synthesis of Heterocycles
- Synthesis and Biological Evaluation
- Biofuel production and bioconversion
- Cyclopropane Reaction Mechanisms
- Immunotherapy and Immune Responses
- Acupuncture Treatment Research Studies
- Immune Response and Inflammation
- Sugarcane Cultivation and Processing
- Force Microscopy Techniques and Applications
- Muscle Physiology and Disorders
- Cytokine Signaling Pathways and Interactions
- Medicinal Plant Pharmacodynamics Research
- Agricultural Practices and Plant Genetics
- Plant Virus Research Studies
- Genetics, Aging, and Longevity in Model Organisms
- Odor and Emission Control Technologies
- Effects of Vibration on Health
- Technology and Human Factors in Education and Health
- Chemokine receptors and signaling
- Silicon and Solar Cell Technologies
- Vibration Control and Rheological Fluids
- Menstrual Health and Disorders
Guangdong Work Injury Rehabilitation Hospital
2021-2024
Fujian Agriculture and Forestry University
2018-2024
Hong Kong Polytechnic University
2020-2021
Third Affiliated Hospital of Sun Yat-sen University
2020
Sun Yat-sen University
2020
Huaqiao University
2016-2019
Chongqing University
2014
Eötvös Loránd University
2008-2012
Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
2004-2007
Institute of Physiology and Basic Medicine
2007
Modern sugarcanes are polyploid interspecific hybrids, combining high sugar content from Saccharum officinarum with hardiness, disease resistance and ratooning of spontaneum. Sequencing a haploid S. spontaneum, AP85-441, facilitated the assembly 32 pseudo-chromosomes comprising 8 homologous groups 4 members each, bearing 35,525 genes alleles defined. The reduction basic chromosome number 10 to in spontaneum was caused by fissions 2 ancestral chromosomes followed translocations chromosomes....
Picolinamide has first been employed as a traceless directing group for the cobalt-catalyzed oxidative annulation of benzylamides with alkynes to synthesize isoquinolines through C–H/N–H bonds activation. Oxygen is used terminal oxidant. This protocol exhibits good functional tolerance and excellent regioselectivity. Both internal can be efficiently applied this catalytic system substrates.
Abstract Background Spinach ( Spinacia oleracea L.) is a dioecious species with an XY sex chromosome system, but its Y has not been fully characterized. Our knowledge about the history of domestication and improvement remains limited. Results A high-quality YY genome spinach assembled into 952 Mb in six pseudo-chromosomes. By combination genetic mapping, Genome-Wide Association Studies, genomic analysis, we characterize 17.42-Mb determination region (SDR) on 1. The chromosomes evolved when...
Most drugs exert their effects via multitarget interactions, as hypothesized by polypharmacology. While these interactions are responsible for the clinical effect profiles of drugs, current methods have failed to uncover complex relationships between them. Here, we introduce an approach which is able relate drug–protein interaction with profiles. Structural data and registered all small-molecule were collected, a series nontarget protein binding sites each drug calculated. Statistical...
A convenient "one-pot" regiospecific synthesis of substituted quinoxalines from o-phenylenediamines and ynones under metal-free conditions has been developed. An intermolecular Michael addition reaction, a dehydration condensation, base-promoted C-α-CH2-extrusion were involved in this procedure, which features high regioselectivity, efficiency, environmental friendliness. Various provided up to 95% yield for 33 examples.
A intramolecular oxidative C(sp2)-N bond formation mediated by hypervalent iodine(iii) to obtain quinoxalines from readily available N-(2-acetaminophenyl)enaminones was developed. tandem process involving PIDA-mediated condensation cyclization and a subsequent elimination postulated, which highly efficient metal-free under mild conditions. Moreover, flexible structural modifications of bearing carbonyl groups are interest for further transformations as building blocks in organic synthesis.
A seesaw-like movement of the relay region upon recovery step myosin was recently simulated in silico. In this model helix tilts around its pivoting point formed by a phenylalanine cluster (Phe481, Phe482, and Phe652), which moves lever arm myosin. To study effect elimination proposed point, these phenylalanines were mutated to alanines two Dictyostelium II motor domain constructs (MF481A, F482A MF652A). The followed fluorescence change Trp501 located region. steady-state transient kinetic...
We present the first in silico model of weak binding actomyosin initial powerstroke state, representing actin binding-induced major structural changes myosin. First, we docked an trimer to prepowerstroke myosin then relaxed complex by a 100-ns long unrestrained molecular dynamics. In few nanoseconds, induced extra primed i.e. further priming lever 18° coupled closure switch 2 loop. demonstrated that induces state specifically through N terminus-activation loop interaction. The applied...
The influence of oxygen defects upon the electronic properties Nb-doped TiO2 has been studied by using general gradient approximation (GGA)+U method. Four independent models (i.e., an undoped anatase cell, cell with a Nb dopant at Ti site (NbTi), Nb-dopant and vacancy (NbTi+VO), interstitial (NbTi+Oi)) were considered. density states, effective mass, Bader charge, charge density, electron localization function calculated. results show that in NbTi+VO both eg t2g levels 3d orbits make...
This randomized controlled trial aimed to evaluate the effects of different whole body vibration (WBV) frequencies on concentric and eccentric leg muscle strength, bone turnover walking endurance after stroke. The study involved eighty-four individuals with chronic stroke (mean age = 59.7 years, SD 6.5) mild moderate motor impairment (Fugl-Meyer Assessment lower limb score: mean 24.0, 3.5) randomly assigned either a 20 Hz or 30 WBV intervention program. Both programs 3 training sessions per...
We investigate the effect of amorphous hydrogenated silicon (a-Si:H) films passivated on surfaces based high-pressure water-vapor annealing (HWA). The effective carrier lifetime samples reaches maximum value after 210°C, 90min HWA. Capacitance-voltage measurement reveals that HWA not only greatly reduces density interface states (Dit), but also decreases fixed charges (Qfixed) mainly caused by bulk defects. change hydrogen and oxygen in film is measured a spectroscopic ellipsometer...
To explore the therapeutic effects of needle warming moxibustion (NWM) combined with trigger point massage on shoulder function and stress responses in elderly patients frozen (FS), providing clinical guidance.
Stingers, evolved from ovipositors, are an important defense organ for the
In order to improve the lateral stability of 4WD vehicle and guarantee its ride performance, this study designs target yaw control system based on sliding mode variable structure control, proposes driving torque distribution algorithm response stable steering characteristic, semiactive suspension double-fuzzy controller. The performance is analyzed during step split-µ road turning. results indicate that combined able turning, reduce body vibration acceleration dynamic deflection travelling...