A5030359455- Nonmelanoma Skin Cancer Studies
- Nail Diseases and Treatments
- Fungal Infections and Studies
- Skin Diseases and Diabetes
- Lymphoma Diagnosis and Treatment
- Cutaneous lymphoproliferative disorders research
- Plant Pathogens and Fungal Diseases
- Urologic and reproductive health conditions
- Cellular transport and secretion
- COVID-19 diagnosis using AI
- Privacy-Preserving Technologies in Data
- Inflammatory Myopathies and Dermatomyositis
- Biomedical Text Mining and Ontologies
- Autoimmune and Inflammatory Disorders
- Cancer Cells and Metastasis
- Microfluidic and Bio-sensing Technologies
- Textile materials and evaluations
- Information Retrieval and Search Behavior
- Multimodal Machine Learning Applications
- Advanced Text Analysis Techniques
- Tattoo and Body Piercing Complications
- 3D Printing in Biomedical Research
- Vascular anomalies and interventions
- Recommender Systems and Techniques
- Cutaneous Melanoma Detection and Management
Peking University First Hospital
2015-2024
Peking University
2015-2024
National Medical Products Administration
2024
National Clinical Research
2024
National Clinical Research Center for Digestive Diseases
2023
Beijing Administration Institute
2019
Abstract Cutaneous T cell lymphoma (CTCL) represents a heterogeneous group of non-Hodgkin distinguished by the presence clonal malignant cells. The heterogeneity cells and complex tumor microenvironment remain poorly characterized. With single-cell RNA analysis bulk whole-exome sequencing on 19 skin lesions from 15 CTCL patients, we decipher intra-tumor inter-lesion diversity patients propose multi-step evolution model. We further establish subtyping scheme based molecular features their...
There is an urgent need to address the effective diagnosis of multiple diseases across various medical institutions while ensuring privacy data in IoT environments. This requires model have ability zero-shot generalization, which can not be satisfied by existing models. To this issue, we propose a two-stage for image diagnosis, based on decoupling and decorrelating. An adversarial architecture built using gradient reversal discriminator improve model's robustness. further mixed correlation...
A 64-year-old man presented with widespread, erythematous-to-violaceous papules that were distributed symmetrically on his trunk, arms, and legs. Skin biopsy revealed palisading granulomatous inflammation surrounded degenerating collagen within the dermis.
A liquid biopsy was established for rapid and sensitive examination of residual tumor cells on surgical margin during Mohs surgery.
To the Editor: Actinic keratosis (AK) is a precancerous skin condition caused by chronic exposure to ultraviolet radiation. It mainly occurs on sun-exposed areas like head and face, leading cosmetic concerns an increased risk of progressing primary squamous cell carcinoma (with 0.60% at 1 year 2.57% 4 years).[1] Photodynamic therapy (PDT) targeted, non-invasive that has been approved in Europe for treatment AK, situ, basal carcinomas. 5-Aminolaevulinic acid (ALA)-based PDT, which utilizes...
Medical report generation with knowledge graph is an essential task in the medical field. Although existing graphs have many entities, their semantics are not sufficient due to challenge of uniformly extracting and fusing expert from different diseases. Therefore, it necessary automatically construct specific graph. In this paper, we propose a vision-knowledge fusion model based on images fully utilize high-quality data diseases languages. Firstly, give general method every domain standards....
Objectives: The aim of this study was to determine the molecular etiology and clinical manifestations a pair Chinese twins affected with epidermolysis bullosa simplex. Pediatricians should pay attention early genetic diagnosis disease. Methods: Histopathological examination HE-stained skin, electron microscopy biopsied normal whole-exome sequencing performed assess pathogenicity conservation detected mutations. Two years later, cutaneous extracutaneous were comprehensively evaluated....
Summary Anuran amphibians are susceptible to infection by intestinal nematodes, but the damage and response mechanisms that occur in their intestines after only partially understood. In this study, disruption Amolops wuyiensis frogs infected with Cosmocercoides n. sp. were revealed through analysis of histopathology, digestive enzyme activity, transcriptome microbiota. Tissue section showed histological inflammation intestine, activity indicated a decrease digestion absorption some...
Despite recent progress in artificial intelligence and computer vision, the lack of data for acral melanoma, a particular type skin disease under nails, makes it difficult to develop its automatic visual diagnosis system. This paper introduces large set dermoscopic images which is annotated by senior dermatologists. It contains 6,066 two categories: subungual hematomas other melanoma symptoms malignant tendency (i.e., just bleeding nails or more critical disorder that requires treatment). We...
Objective To investigate imaging characteristics of human skin in different sites by using 20-MHz and 50-MHz high-frequency ultrasonography, to compare the reliability thickness measurement above two approaches ultrasonography. Methods A total 39 healthy volunteers aged 18-39 years were enrolled into this study. Then, ultrasonography separately performed image 20 on body, epidermis dermis measured evaluated 3 dermatologists independently. The ultrasonic images analyzed, intraclass...