A5100434293- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and Carotid Artery Diseases
- Spinal Fractures and Fixation Techniques
- Moyamoya disease diagnosis and treatment
- Infectious Diseases and Tuberculosis
- Radiomics and Machine Learning in Medical Imaging
- Cerebral Venous Sinus Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Neurosurgical Procedures and Complications
- Aortic Disease and Treatment Approaches
- Meningioma and schwannoma management
- Orthopedic Infections and Treatments
- Aortic aneurysm repair treatments
- Stock Market Forecasting Methods
- Respiratory viral infections research
- COVID-19 and Mental Health
- Thyroid and Parathyroid Surgery
- Spinal Cord Injury Research
- Long-Term Effects of COVID-19
- Gut microbiota and health
- Epigenetics and DNA Methylation
Capital Medical University
2016-2025
Beijing Institute of Neurosurgery
2016-2025
Henan Agricultural University
2023-2025
Shenyang Normal University
2025
Nanjing Medical University
2025
Nanjing University
2025
Nanjing General Hospital of Nanjing Military Command
2025
Beijing Tian Tan Hospital
2018-2024
Central South University
2015-2024
China Electric Power Research Institute
2024
Determining the grade and molecular marker status of intramedullary gliomas is important for assessing treatment outcomes prognosis. Invasive biopsy pathology usually carries a high risk tissue damage, especially to spinal cord, there are currently no non-invasive strategies identify pathological type gliomas. Therefore, this study aimed develop machine learning model assist doctors in identifying glioma mutation markers.A total 461 patients from two institutions were included, their...
Evaluating rupture risk in cerebral arteriovenous malformations currently lacks quantitative hemodynamic and angioarchitectural features necessary for predicting subsequent hemorrhage. We aimed to derive rupture-related of construct an ensemble model This retrospective study included 3 data sets, as follows: training test sets comprising consecutive patients with untreated who were admitted from January 2015 June 2022 a validation set unruptured received conservative treatment between 2009...
The researchers detect viruses through various analyses based on three targets: nucleic acids, antigens, and antibodies.
Aim Aortic aneurysm is characterized by localized expansion and damage to the vessel wall. While apolipoprotein B (ApoB) has been linked atherosclerosis, its causal relationship with aortic remains unclear. This study used a Mendelian randomization (MR) approach explore relationships between ApoB, aneurysm, potential mediators. Material methods Single nucleotide polymorphism (SNP) data related A1 (ApoA1), triglycerides, frailty index, were obtained from large-scale genome-wide association...
Abstract The Jiangchuan biota is a diverse macrofossil assemblage from the Jiucheng Member of Dengying Formation, in uppermost Ediacaran (Sinian) Eastern Yunnan, Southwest China. This well known for its macroalgal fossils preserved as carbonaceous compressions, but co‐occurring taxa have remained poorly documented. Here, we present new discoidal macrofossils biota, which interpret eumetazoan‐grade organisms uncertain affinities. These disc‐like are smooth, well‐defined impressions with...
Abstract Clinical nutritional support is recognized by Klinefner's Surgery as one of the four pivotal advancements in surgical practice during 20th century. Surgeons regard clinical nutrition a “life‐saving” discipline, preserving lives numerous critically ill patients and facilitating success many procedures. Parenteral (PN) serves crucial component therapy, while range complications associated with total parenteral (TPN) can significantly undermine efficacy patient treatment. Impaired...
There are quite a few controversies on the surgical management of single-segment thoracic spinal tuberculosis with neurological deficits (STSTND). In this study, clinical efficacy and feasibility one-stage posterior-only transpedicular debridement, interbody fusion, posterior instrumentation for treating STSTND in adults were retrospectively evaluated.Thirty-four cases underwent fusion at same institution from January 2003 to 2013. Follow-up time was 34.4 ± 10.2 months (range, 18-48 months),...
Sublesional osteoporosis predisposes individuals with spinal cord injury (SCI) to an increased risk of low-trauma fracture. The aim the present work was investigate effect treatment resveratrol (RES) on sublesional bone loss in cord-injured rats.Complete SCI generated by surgical transaction at T10-12 level. Treatment RES (400 mg·kg(-1) body mass per day(-1) , intragastrically) initiated 12 h after surgery for 10 days. Then, blood collected and femurs tibiae were removed evaluation effects...
Aim: The aim of this retrospective clinical study is to evaluate the long-term outcomes for single-stage transpedicular debridement, posterior instrumentation and fusion in management thoracic thoracolumbar spinal tuberculosis adults.Methods: Fifty-nine adult patients with underwent fusion. These were followed a minimum 5 years. Patients assigned one two groups according infected anatomic segment. In group, there 28 cases (17 males, 11 females) mean age 38.9 years; 31 (19 12 40.3 All...
Intracerebral hemorrhage (ICH) is the most devastating subtype of stroke, but effective prevention and treatment strategies are lacking. Recently, gut microbiome its metabolitesis considered to be an influencing factor stroke. However, little known about effects on ICH host metabolic activity. Therefore, we used 16S sequencing, macrogenomics sequencing untargeted metabolomics explore differences in microbial-metabolome interactions between patients with intracerebral healthy control...
Abstract Background Oxidative stress and endothelial cell dysfunction induced by high-altitude hypoxia have important roles in the pathological process of pulmonary hypertension (HAPH). Tannins present Terminalia bellirica (Gaertn.) Roxb. (TTR) pharmacological activities that produce oxidation resistance exert anti-inflammatory effects. Whether TTR exerts a protective effect on HAPH remains unknown. Methods A rat model was established. The mean arterial pressure (mPAP) animals measured,...
This is a retrospective case-control study.The surgical approaches to cervicothoracic spinal tuberculosis (CTSTB) were controversial. The aim of this research retrospectively compare the efficacy and feasibility anterior-only (AO) approach, combined anterior posterior (AP) surgeries, posterior-only (PO) approach for treatment CTSTB.AO was undertaken in 20 patients (group A), AP fusion carried out 18 B), PO surgery performed 21 C). Surgery duration, intraoperative blood loss, length...
Patients with hypertensive intracerebral hemorrhage (ICH) have a high hematoma expansion (HE) incidence. Noninvasive prediction HE helps doctors take effective measures to prevent accidents. This study retrospectively analyzed 253 cases of intraparenchymal hematoma. Baseline non-contrast-enhanced CT scans (NECTs) were collected at admission and compared subsequent CTs determine the presence HE. An end-to-end deep learning method based on was proposed automatically segment region, region...