A5002564443- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Spinal Cord Injury Research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Immunology Research
- Tracheal and airway disorders
- Nerve injury and regeneration
- Neurogenesis and neuroplasticity mechanisms
- Pediatric health and respiratory diseases
- Virus-based gene therapy research
- COVID-19 and Mental Health
- Parvovirus B19 Infection Studies
- Animal Virus Infections Studies
- Pneumonia and Respiratory Infections
- Polyomavirus and related diseases
- Energy Harvesting in Wireless Networks
- RNA modifications and cancer
- interferon and immune responses
- Neuroinflammation and Neurodegeneration Mechanisms
- COVID-19 and healthcare impacts
- MicroRNA in disease regulation
- Cerebrospinal fluid and hydrocephalus
- Neonatal Respiratory Health Research
- Pain Mechanisms and Treatments
- Ginseng Biological Effects and Applications
Jilin Agricultural University
2025
National Institute for Viral Disease Control and Prevention
2016-2025
Nanchang University
2020-2025
Jiangxi Provincial People's Hospital
2022-2025
First Affiliated Hospital of Jiangxi Medical College
2023-2025
Xiangya Hospital Central South University
2024-2025
Central South University
2023-2025
First Affiliated Hospital of Nanchang University
2020-2024
Qiqihar Medical University
2014-2024
Jiujiang University
2024
To investigate the current genotypes of circulating human adenovirus (HAdV) strains, we molecularly genotyped HAdV in nasopharyngeal aspirates (NPAs) patients with acute lower respiratory tract infections (ALRTIs) and attempted to determine their associations clinical symptoms. A total 4751 NPA samples were collected from admitted Hunan Provincial People's Hospital September 2007 March 2014, which 447 (9.4%) positive. Fourteen different types identified; 1 7 (HAdV 1-7) identified 95.7%...
Pneumonia is a serious public health issue and concerned around the world. This study to investigate association between viral load in children with human adenovirus (HAdV) pneumonia disease severity. A total of 1313 cases hospitalized Hunan Provincial People's Hospital due community acquired (CAP) from April 2011 May 2014 were enrolled this study. Samples nasopharyngeal aspirate collected for cohort. WHO criteria CAP grading was emerged severity classification. Real-time fluorescence...
Human rhinovirus C (HRV-C) is a newly identified genotype of HRV found in patients with respiratory tract infections (RTIs); however, its epidemiological profile and clinical characteristics are not well understood. In this study, Chinese children RTIs were screened for HRV-C their analyzed. From December 2006 to November 2007, 406 nasopharyngeal aspirates from younger than 14 years age other common viruses by PCR or reverse transcription-PCR. Two-hundred twenty-four (55.2%) the specimens...
There are limited data on the prevalence and clinical molecular characterization of human respiratory syncytial virus (HRSV) in children with acute tract infections (ARTIs) China. From December 2006 to March 2009, 894 nasopharyngeal aspirates (NPAs) were collected from under 14 years age ARTIs. Samples screened for HRSV genotyped by reverse transcription-PCR (RT-PCR) sequencing. Demographic information was recorded. A total 38.14% (341/894) samples positive HRSV. Phylogenetic analysis...
Abstract Background Human adenovirus (HAdV) is an important agent causing respiratory tract infection in children. Information on the epidemiological and clinical features of HAdV limited children with acute infections (ARTIs) China, especially those a novel genotype, Ad55. Methods In total, 1169 nasopharyngeal aspirates were collected from younger than 14 years ARTIs between November 2006 2009. The polymerase chain reaction (PCR) was used to screen HAdVs. All PCR-positive products...
Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) are two common viral pathogens in acute lower respiratory tract infections (ALRTI). However, the association of load with clinical characteristics is not well-defined ALRTI. To explore correlation between RSV HMPV children hospitalized for ALRTI Lanzhou, China. Three hundred eighty-seven were enrolled. Nasopharyngeal aspirates (NPAs) sampled from each children. Real-time PCR was used to screen RSV, HMPV, twelve additional...
This study aimed to investigate the knowledge-attitude-practice (KAP) of Chinese college students regarding COVID-19 and evaluate their psychological status against background outbreak.This was a cross-sectional study.This covered 31 provinces, municipalities autonomous regions mainland China.The participants, who were with ordinary full-time status, surveyed anonymously on KAP by using self-made questionnaires. In addition, Self-Rating Anxiety Scale used assess students.The online among...
Species A rotaviruses (RVs), which belong to the family Sedoreoviridae and contain a genome of 11 segmented dsRNA segments, are leading cause severe acute gastroenteritis in infants children younger than 5 years age. We previously developed strategy recover rotavirus vaccine strain LLR from cloned plasmids. Here, we report an improved reverse genetics system for by combining two or three transcriptional cassettes single plasmid, substantially enhances rescue efficiency 66.7% (8/12) 91.7 %...
Patients with spinal cord injury (SCI) may develop depression, which can affect their rehabilitation. However, the underlying mechanism of depression in SCI patients remains unclear. Previous studies have revealed increased p38 MAPK phosphorylation rat hippocampus after SCI, accompanied by depression-like behaviors. role signaling pathway SCI-induced In this study, we used an aneurysm clip-induced model to investigate whether is associated behaviors rats SCI. Behavioral testing that...
This study examines global trends in depression incidence among women of childbearing age (WCBA) from 1992 to 2021 and projects future through 2030. Using data the Global Burden Disease (GBD) applying age-period-cohort (APC) model, we analyzed temporal patterns across groups, periods, birth cohorts. The WCBA increased 77.57 million cases 127.02 2021, with age-standardized rate (ASIR) rising 5675.52 6490.04 per 100,000 people. estimated annual percentage change (EAPC) was -0.21 (95 % CI: 0.47...
Human parainfluenza viruses (HPIVs) are an important cause of acute lower respiratory tract infections (ALRTIs). HPIV-4, a newly identified virus, has been associated with severe ALRTIs recently. A total 771 nasopharyngeal aspirate samples were collected from hospitalized children between March 2010 and February 2011. HPIVs detected by Nest-PCR, other known RT-PCR PCR. All amplification products sequenced. in 151 (19.58%) patients, whom 28 (3.63%) positive for 12(1.55%) HPIV-1, 4 (0.51%)...
Severe pneumonia is a major cause of mortality in children. The present study evaluated the diagnostic value serum C-reactive protein (CRP) levels for cases severe pneumonia. A total 862 children, hospitalized acute respiratory tract infections, were between September 2008 and February 2011; CRP measured all Bacterial identification was performed, while polymerase chain reaction used to detect 12 viruses. Multivariate logistic regression analysis performed with independent [CRP, proportion...
Abstract Hepatitis A virus (HAV) is a hepatotropic picornavirus that causes acute liver disease worldwide. Here, we report on the identification of novel hepatovirus tentatively named Marmota Himalayana (MHHAV) in wild woodchucks ( Himalayana) China. The genomic and molecular characterization MHHAV indicated it most closely related genetically to HAV. has wide tissue distribution but shows tropism for liver. morphologically structurally similar pattern its codon usage bias also consistent...
Lower respiratory tract illness is a major cause of morbidity and mortality in children worldwide, however, information about the epidemiological clinical characteristics LRTIs caused by HMPV HBoV China limited.Human bocavirus (HBoV) human metapneumovirus (HMPV) are two important viruses for with lower infections (LRTI). We aimed to assay correlation between viral load LRTI Changsha, China.Nasopharyngeal aspirates (NPAs) from were collected. Real-time PCR was used screen HMPV. Analyses...
Introduction Etiology studies of severe acute respiratory infections (SARI) in adults are limited. We studied potential etiologies SARI among six countries using multi-pathogen diagnostics. Methods enrolled both with (acute illness onset fever and cough requiring hospitalization) asymptomatic (adults hospitalized non-infectious illnesses, non-household members accompanying patients, from outpatient departments, community members) each country. Demographics, clinical data, nasopharyngeal...
Purpose: This study aimed to assess the knowledge, attitude and practice (KAP) towards COVID-19 of Chinese college students during outbreak identify determinants considerably associated with KAP. Methods: An online cross-sectional questionnaire survey was conducted in February 2020 China recruit participants on Wen-Juan-Xing platform. A self-made used KAP COVID-19. Results: The average scores COVID-19-related among were 32.16 ± 4.09, 16.84 3.18 15.36 1.83, respectively. correct response rate...
This study aims to described the epidemiology and genotypic diversity of Human metapneumovirus (HMPV) impact SARS-CoV-2 on prevalence HMPV in hospitalized children with Acute respiratory tract infections (ARTIs) Beijing, China.From April 2018 March 2019 from September 2020 August 2021, nasopharyngeal aspirates (NPAs) ARTIs Beijing were collected subjected real-time polymerase chain reaction tests for HMPV. Then genotyping, detection 15 common viruses clinical characteristics analyzed...
Abstract Aims Neutrophils play a pivotal in immunity and inflammation. We aim to investigate the prevalence of neutropenia United States. Methods In this cross-sectional study, participants from National Health Nutrition Examination Survey (NHANES) (2011–2018) were enrolled. Demographic information, hematologic measurements, smoking status all collected for participants. All statistical analyses performed utilizing NHANES survey weights. Covariate-adjusted linear regression was used compare...
Acute respiratory tract infections (ARTIs) causes high amounts of morbidity and mortality worldwide every year. Human metapneumovirus (HMPV) is a major pathogen ARTIs in children. In this study, we aimed to investigate the epidemiology genotypic diversity HMPV children hospitalized with Beijing, China.Hospitalized aged < 14 years were enrolled from April 2017 March 2018; nasopharyngeal aspirates collected subjected real-time polymerase chain reaction tests for HMPV. HMPV-positive samples...