Study Design: In vitro experiment using degenerated human ligamentum flavum (LF) and various inflammatory cytokines. Objectives: To examine the effect of cytokines on LF cells to identify their roles in pathogenesis hypertrophy ossification. Summary Background Data: Spinal stenosis is caused, part, by ossification LF, which are induced degenerative processes (ie, increased collagen synthesis chondroid metaplasia) ligament fibroblasts. Degenerated intervertebral disk spontaneously produces...

The objective of this study was to examine FoxO expression and function in meniscus. In menisci from human knee joints with osteoarthritis (OA), FoxO1 3 were significantly reduced compared normal young old donors. also mouse during aging OA induced by surgical meniscus destabilization or mechanical overuse. Deletion combined FoxO1, 3, 4 deletions abnormal postnatal development mice these mutant spontaneously displayed pathology at 6 mo. Mice Col2Cre-mediated deletion FoxO3 FoxO4 had but more...

In Brief Study Design. A prospective case control study. Objectives. To investigate the risk of a fall by using functional mobility tests in patients with lumbar spinal stenosis (LSS) via comparison knee osteoarthritis (KOA). Summary Background Data. LSS is degenerative arthritic disease spine that results decreasing function, impaired balance, and gait deficit, increased levels leg back pain. This physical impairment may result an later process, as shown KOA. However, there has been no...

In vitro experiment using rabbit nucleus pulposus (NP) cells seeded in atelocollagen scaffolds under the stimulation of growth factors.To demonstrate effect anabolic factors NP cultured type I and II.Atelocollagen provides intervertebral disc (IVD) for a biocompatible environment to produce extracellular matrix. IVD with exogenous transforming factor-beta 1 (TGF-β1) bone morphogenetic protein-2 (BMP-2) also render an increase matrix synthesis. However, atelocollagens was not elucidated...

Abstract Block‐type biphasic calcium phosphate (BCP) carriers are more effective at delivering recombinant human bone morphogenetic protein‐2 (rhBMP‐2) in various clinical situations than particle‐type carriers, due to their potential for highly successful three‐dimensional regeneration. The aim of this study was confirm the bone‐regenerative capabilities BCP blocks with a low hydroxyapatite/β‐tricalcium ratio (20/80) combined collagen (10% wt) as an rhBMP‐2 delivery system craniofacial...

Mohawk is enriched in meniscal tissue and promotes meniscus cell phenotype, enhances repair, protects against cartilage destruction mice.

Background: Anterior cruciate ligament (ACL) reconstruction is the current standard of care for ACL tears. However, results are not consistently successful; autografts or allografts have certain disadvantages; and synthetic grafts had poor clinical results. Purpose: To determine if recellularization decellularized tendons combined with mechanical stimulation in a bioreactor could replicate properties native be successfully used vivo. Study Design: Controlled laboratory study. Methods:...

No AccessJournal of UrologyPEDIATRIC UROLOGY1 May 2001IMPLICATIONS OF PRENATAL ULTRASOUND SCREENING IN THE INCIDENCE MAJOR GENITOURINARY MALFORMATIONS WILLIAM J. CROMIE, KWANG LEE, KARA HOUDE, and LEWIS HOLMES CROMIEWILLIAM CROMIE , LEEKWANG LEE HOUDEKARA HOUDE HOLMESLEWIS View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)66391-4AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose:...

To date, there have been no prospective, objective studies comparing the accuracy of MRI, myelo-CT and myelography.The purpose this study is to compare diagnostic predictive values MRIs, myelo-CTs, myelographies.Myelographies with dynamic motion views, MRIs exercise treadmill tests were performed in 35 cases.The narrowest AP diameter dural sac was measured by myelography.At pathologic level, cross-sectional area (D-CSA) calculated MRI Myelo-CT.The time first symptoms (TAF) total ambulation...

Biologic augmentation for rotator cuff repair is a challenging treatment in patients with chronic large, massive, and irreparable injuries. Particularly, the use of an extracellular matrix (ECM) patch such as dermal tissue offered improved biomechanical properties previous studies. Cytokines induce cell chemotaxis, proliferation, synthesis, differentiation. Moreover, osteoinductive growth factors bone morphogenetic protein-2 (BMP-2) affect formation new fibrocartilage lesions. However,...

IEEE 802.15.4-based ZigBee routing is based on ad hoc on-demand distance vector (AODV) so that states the possibility of building mesh network with data dissemination manner similar to network. Although focuses low rate, overhead for route discovery may interfere traffic. Since it affects performances such as end-to-end delay and packet delivery ratio in dense networks, necessary protocols improving scalability are designed. In this paper, we present a protocol ZigBee, called cluster label...

In this article, we investigate 4G network architecture and consider two underlying layers: PHY MAC. We compare models of wireless access network: pure all-IP subnet based networks. The model is simple cost-efficient but causes implementation issues mobility management resource coordination. contrast, the enables layer 2 3 handoffs to be executed independently, deploying several points under an router. Further, handle various cases efficiently according traffic class mobility, present...

Decellularized tissues have been successfully used in tissue engineering and regenerative medicine for the purpose of removing antigens present cellular components. However, this decellularization technique uses ionic solutions or chemical treatments such as enzyme that might damage biophysical properties reduce physical strength tissue. This study aimed to improve decellularized tissues. We designed a bioreactor can repeatedly deliver stimulation, tensile torsional deformation, upper lower...

This study examines the hypothesis that injectable collagen gel can be an effective carrier for recombinant human bone morphogenetic protein-2 (rhBMP-2)'s localization to healing tendon-bone interface. In 36 mature New Zealand White rabbits, upper long digital extensor tendon was cut and inserted into proximal tibial tunnel. Then a rhBMP-2-containing injected tunnel interface, using syringe. Histological biomechanical assessments of interface were conducted at 3 6 weeks after implantation....

In Brief Study Design. A finite element analysis. Objective. To evaluate the differences between surgical techniques in terms of effects arthrodesis on adjacent segments. Summary Background Data. Augmentation with posterior rigid fixation combined transpedicular screw insertion, which is one most popular for lumbar arthrodesis, shows benefits immediate stabilization and a higher fusion rate but reportedly correlated greater stress However, increased segments needs further evaluation because...

Aim: To mimic the ultrastructural morphology of meniscus with nanofiber scaffolds coupled controlled growth factor delivery to modulate cellular performance for tissue engineering menisci. Methods: The authors functionalized collagen nanofibers by conjugating heparin following factors sustained release: PDGF-BB, TGF-β1 and CTGF. Results: Incorporating increased human meniscal synovial cell viability, proliferation infiltration in vitro, ex vivo vivo; upregulated key genes involved...

Recently, wireless multimedia services have been growing because of the spread various applications. Hence, time division duplex (TDD) systems and their crossed-slot interference problems in a cellular environment attracting interests. Considering large signaling overhead between cells, decentralized slot allocation (TSA) strategy is suitable for practical implementation. Thus, Fixed-TSA which fixes same ratio uplink downlink slots all cells adopted commercial WiBro (IEEE802.16e Mobile...

To determine the feasibility of volumetric criteria without anatomic exclusion for selection right posterior sector (RPS) grafts adult-to-adult living donor liver transplantation (LDLT), we reviewed and compared our transplant data RPS lobe (RL) grafts. Between January 2008 September 2010, LDLT was performed 65 times at institute; 13 procedures (20%) were with [the (PS) group], 39 (60%) RL (the group). The volumetry livers showed that volume 39.8% ± 7.6% total volume. Ten donors had to...