In Brief Study Design. Retrospective study of the difference heterotopic ossification (HO) occurrence according to 3 different types prosthesis. Objective. This was designed investigate HO type Summary Background Data. is defined as formation bone outside skeletal system. Reported rate in cervical artificial disc replacement (ADR) unexpectedly high and varied. But influencing factors ADR have not been elucidated well. The prosthesis-related for making were investigated this study. Methods. A...

Pelvic reconstruction after sacral resection is challenging in terms of anatomical complexity, excessive loadbearing, and wide defects.Nevertheless, the technological development 3D-printed implants enables us to overcome these difficulties.Here, we present a case osteosarcoma surgically treated with hemisacrectomy using implant.The implant was printed as customized titanium prosthesis from 3D real-sized patient's CT images.It consisted mostly porous mesh incorporated dense strut.After...

The majority of earlier studies the parameters sagittal balance did not consider influence spinal muscles on alignment.To analyze relationship between paraspinal muscle (quantity and quality) alignment in elderly patients.We reviewed 50 full-spine lateral standing radiographs lumbar magnetic resonance images patients at a single center. radiographic examined were thoracic kyphosis, lordosis (LL), vertical axis, pelvic tilt, sacral slope, incidence (PI). muscularity (LM; quantity) fatty...

We report a series of epidural hematomas which cause neurologic deterioration after spinal surgery, and have taken risk factors prognostic into consideration.We retrospectively reviewed the database 3720 cases spine operation in single institute over 7 years (1998 April-2005 July).Nine patients who demonstrated surgery required surgical decompression were identified.Factors postulated to increase postoperative hematoma improve outcome investigated.The incidence was 0.24%.Operation sites...

The purpose of this study is to investigate the risk factors for recurrence after successful percutaneous endoscopic lumbar discectomy (PELD). Recently, PELD has become most common surgical technique. However, there are only a few studies on causing reappearance symptoms. Between January 2002 and December 2004, 42 patients with recurrent disc herniation were classified as group who underwent satisfactory result randomly selected non-recurrent group. For all patients, we analyzed medical...

A prospective analysis.The purpose of this study was to compare the clinical and radiologic outcomes cervical artificial disc replacement (C-ADR) combined with anterior discectomy fusion (ACDF) 2-level ACDF in patients disease.Adjacent segment degeneration is a long-term complication ACDF, estimated affect 25% within 10 years initial surgery. Two-level leads substantially greater increase intradiscal pressure than one-level fusion. It has been demonstrated that C-ADR maintains motion at...

Object The objective of this study was to evaluate the invasiveness microendoscopic discectomy (MED) in comparison with microscopic (MD) by measuring serum levels creatine phosphokinase (CPK)-MM and lactate dehydrogenase (LDH)-5, comparing visual analog scale (VAS) scores postoperative pain. Methods This included a group 15 patients who underwent surgery using MED MD, both for single-level unilateral herniated nucleus pulposus. CPK-MM LDH-5 were measured at admission after 1, 3, 5 days...

The goal of this study was to determine the relationship between cervical spine sagittal alignment and clinical outcomes after laminoplasty in patients with ossification posterior longitudinal ligament (OPLL).Fifty consecutive who underwent a for OPLL January 2012 2013 were followed up at least 1 year analyzed study. Standing plain radiographs spine, CT (midsagittal view), MRI (T2-weighted view) obtained (anteroposterior, lateral, flexion, extension) pre- postoperatively. Cervical assessed...

Abstract BACKGROUND Spinal cord glioma grade IV is a rare, diffuse midline glioma. H3 K27M-mutant was classified in different entity the 2016 World Health Organization (WHO) classification recently. No reports about prognosis of spinal are available yet. OBJECTIVE To analyze prognostic factors for IV. METHODS Twenty-five patients with who underwent surgery single institute were selected. All histologically confirmed as glioblastoma or “diffuse K27M-mutant” by WHO central nervous system...

Neural stem cells have been proposed as useful vectors for treating diseases in the CNS, but their utility is severely limited by lack of accessibility. Brain development ongoing extensively early postnatal life. However, it unclear whether that differentiate into neurons exist blood during We showed this experiment neural markers (NeuN, neurofilament, MAP2, GFAP) are expressed and long cytoplasmic processes elaborated cultured human cord monocytes prepared from newborn umbilical blood....

The low survival rate of graft stem cells after transplantation into recipient tissue is a major obstacle for successful cell therapy. After the site spinal cord injury, face not only hypoxia due to oxygen conditions, but also lack nutrients caused by damaged tissues and poor vascular supply. To improve therapeutic grafting injured cord, we examined effects cotransplanting mouse neural (mNSCs) adipose tissue-derived mesenchymal (AT-MSCs) on mNSC viability. viability mNSCs in coculture with...

In Brief Study Design. A prospective, randomized, double-blind clinical trial. Objective. To compare the effect of ramosetron with that ondansetron on opioid-based IV patient-controlled analgesia (PCA) related postoperative nausea and vomiting (PONV) in highly susceptible patients after lumbar spine surgery. Summary Background Data. Optimal pain management is important to facilitate early mobilization Opioid associated a high incidence PONV. Among currently available 5-hydroxytryptamine...

The authors conducted a retrospective observational study using kinetic MR imaging to investigate the relationship between instability, abnormal sagittal segmental motion, and radiographic variables consisting of intervertebral disc degeneration, facet joint osteoarthritis (FJO), degeneration interspinous ligaments, ligamentum flavum hypertrophy (LFH), status paraspinal muscles.Abnormal defined as > 10 degrees angulation 3 mm translation in plane, was investigated 1575 functional spine units...

A retrospective study.To analyze adjacent segment degeneration (ASD) in 2-level anterior cervical discectomy, comparing fusion with stand-alone cages [anterior discectomy and (ACDF)-CA] cage plate constructs (ACDF-CPC) respect to clinical outcomes radiologic changes.ACDF using a or construct is popular procedure. However, there lack of knowledge concerning ASD between the 2 procedures.A total 42 consecutive patients who underwent ACDF-CA ACDF-CPC for disk disease completed years follow-up...

We investigated whether transplantation of a three-dimensional cell mass adipose-derived stem cells (3DCM-ASCs) improved hind limb functional recovery by the stimulation angiogenesis and neurogenesis in spinal cord injury. In in-vitro experiments, we confirmed that 3DCM-ASCs differentiated into CD31-positive endothelial cells. To evaluate therapeutic effect vivo, PBS, human adipose tissue-derived cells, were transplanted injury model. The injured remained differentiated. Transplantation...

Object. Granulocyte—macrophage colony—stimulating factor (GM-CSF) is a potent hemopoietic cytokine that stimulates stem cell proliferation in the bone marrow and inhibits apoptotic death leukocytes. Its effects central nervous system, however, are still unclear. The present study was undertaken to determine if GM-CSF can rescue neuronal cells from apoptosis improve neurological function spinal cord injury (SCI) model. Methods. To effect of on death, authors used staurosporine-induced model...