A5103853615- Pharmaceutical Practices and Patient Outcomes
- Drug-Induced Hepatotoxicity and Protection
- Diabetes Management and Education
- Respiratory and Cough-Related Research
- Diabetes Management and Research
- Chronic Disease Management Strategies
- Inhalation and Respiratory Drug Delivery
- Cancer Treatment and Pharmacology
- Child Nutrition and Water Access
- Pharmacogenetics and Drug Metabolism
- Atrial Fibrillation Management and Outcomes
- Pharmacovigilance and Adverse Drug Reactions
- Liver Disease Diagnosis and Treatment
- Antibiotic Use and Resistance
- Innovations in Medical Education
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Viral gastroenteritis research and epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Chronic Lymphocytic Leukemia Research
- HIV/AIDS Research and Interventions
- Medication Adherence and Compliance
- Urinary Bladder and Prostate Research
- Bariatric Surgery and Outcomes
- Surgical site infection prevention
- Advanced Drug Delivery Systems
Kathmandu University
2013-2025
Dhulikhel Hospital
2020-2024
International Pharmaceutical Federation
2023
BACKGROUND: Antitubercular drugs cause derangement of hepatic function revealed by clinical examination and abnormal liver test results. Potential hepatotoxicity some the first-line antitubercular agents remains a problem, especially during initial period treatment. OBJECTIVE: To determine incidence drug—induced in Nepalese urban population assess risk factors. METHOD: Fifty patients diagnosed with active tuberculosis infection normal pretreatment were monitored clinically as well...
This study aimed to develop hydrophilic matrix based controlled release gastroretentive drug delivery system of ofloxacin and conducting its in vitro vivo evaluations. Effervescent floating was prepared utilizing Box–Behnken statistical design with 3 factors, levels 15 experimental trials. Formulation optimization done by setting targets on selected responses. In studies were carried out for the optimized formulation 12 healthy human volunteers obtained pharmacokinetic parameters compared...
Patients with atrial fibrillation (AF) are at increased risk of stroke. Poor knowledge AF in general population contributes to under-detection and treatment delay. Therefore, this study aimed assess level awareness among public Dhulikhel municipality, Nepal. This was a cross sectional involving quantitative approach using self-administered questionnaire. Participants age ≥ 50 years from wards 4, 5, 6 7 municipality were enrolled. English version AFKAT (Atrial Fibrillation Knowledge...
Enteric fever is endemic in Nepal and its economic burden unknown. The objective of this study was to estimate the cost illness due enteric (typhoid paratyphoid) at selected sites Nepal.
Tuberculosis is one of the foremost public health problems causing an enormous burden suffering and deaths. Chemotherapy basic approach to clinical tuberculosis control. 1Essential anti-tuberculosis drugs are Isoniazide (INH), Rifampicin (RMP), Pyrazinamide (PZA), Ethambutol (E) Streptomycin (S). Department Pharmacy, KU, KUTH, Dhulikhel conducted this study in collaboration with German-Nepal Project (GENETUP) Korea-Thimi Friendship Hospital during March 2005 July 2005. Total 70 newly...
Abstract Background India contributes 15% of the total global maternal mortality burden. An increasing proportion these deaths are due to Pregnancy Induced Hypertension (PIH), Gestational Diabetes Mellitus (GDM), and anaemia. This study aims evaluate effectiveness a tablet-based electronic decision-support system (EDSS) enhance routine antenatal care (ANC) improve screening management PIH, GDM, anaemia in pregnancy primary healthcare facilities Telangana, India. The EDSS will work at two...
A needs-based approach is desirable for the transformation of pharmaceutical education, and to link education with health needs populations national priorities. There are varying levels data in literature on status all six World Health Organization (WHO) regions, especially context identification evidence-based policy interventions. The framework this study was FIP Development Goals.
bring terrible social misery, psychological distress and suffering to the patients relatives [2].In Nepal cancer is still believed be a disease of death though advances in medical science have changed perception towards certain extent [3].Some types been proven curable now.Though being effective, chemotherapeutic agents are frequently associated with several Adverse Drug Reactions (ADRs).ADRs chemotherapy considerable economic as well clinical costs they often lead hospital admission,...
United Nations Sustainable Development Goal 3 outlines the target of reducing premature mortality from non-communicable diseases by one third through prevention and treatment 2030. In low middle-income countries (LMICs) like Nepal, a significant number people do not have accessible affordable healthcare services available to them, leading self-medication practices (SMP). Limited numbers health professionals, ineffective regulation easy availability prescription medicines encourage use...
Abstract Background Implementation of population-based surveys is resource intensive and logistically demanding, especially in areas with rapidly changing demographics incomplete or no enumeration the underlying population their residences. To remove need for pre-enumeration to simplify field logistics healthcare utilization survey used Surveillance Enteric Fever Asia Project Nepal, we incorporated a geographic information system–based geosurvey mapping system into single-stage cluster...
Diabetes care incorporates multiple integrated elements like self-care practices, patient education and awareness, societal support, equitable access to healthcare facilities trained professionals, commitment from the diabetes associations government policies. There is a dearth of research exploring barriers experienced by both People with Type 1 (PwT1D) 2 (PwT2D) in accessing holistic care. This study thus aimed at perceived among PwT1D PwT2D services urban rural areas Nepal. was...
The study carried out presents causes of poor compliance among the patients using inhaler devices. Evaluation patient's prior knowledge and practice inhalers improvement on after counseling intervention through standard guidelines were outcome measures this study. It was hypothesized that pharmaceutical gives better outcome. There lesser in inhalation technique score females than males furthermore female falling under resting category mostly above age 60 years. Comparing mean scores before...
This commentary article highlights the status of clinical pharmacy education in Nepal, explores challenges and solutions sustainably reintroducing Post-Baccalaureate Doctor Pharmacy (PharmD, Post-Bac) as was previously launched by Kathmandu University (KU) Department 2010, suggests a few prospects forward. Clinical practice has remained on sidelines subordinate to physicians Nepal. KU PharmD (Post-Bac.) postgraduate program establish professional identity pharmacists country. However,...
Since the introduction of Highly Active Anti Retroviral therapy (HAART) by World Health Organization in 1996, it has been employed method drug use HIV management. Involvement multiple drugs regimen, also invited complications and side effects is one them. High chances occurrence called for need proper identification management tools each HAART user highlighted importance individualized therapy. The aim study prescription pattern regimen; frequency regimen change its major causes; side- from...
Heart failure is the common cardiovascular diseases among people of south Asian Origin including Nepal. The prevalence increases with age and accounts for most adult hospital admissions. objective study was to prescribing patterns drugs used in heart failure. included both in-patients outpatients conducted at 2 different hospitals inside Kathmandu valley one outside valley, Dhulikhel. period nearly four months number patients 156, which total 71 Males (52.59 %) 64 Females (47.4%). Subjects...
Aim: To compare the safety and efficacy of two commercially available prostaglandin analogues, misoprostol dinoprostone as cervical ripening agents. Methods: Patients with a term, vertex, singleton pregnancy Bishop score 4 or less were randomly assigned to receive pessary (n = 35, 50 μg intravaginally, maximum dose up six pessary) gel 31, 0.5 mg intracervically; administered twice 6hrs apart). monitored throughout period. If there was no progress in dilatation effective uterine contraction...
Asthma and Chronic obstructive pulmonary disease (COPD) are chronic respiratory conditions characterized by airflow obstruction symptoms. Adherence to prescribed inhaler therapy correct inhalation technique essential for effective management optimal control. However, non-adherence incorrect common challenges faced patients with asthma COPD, leading suboptimal treatment outcomes increased healthcare burden.
Background: Gestational Diabetes Mellitus increased almost 30% in many countries, including underdeveloped countries and same Nepal. Hospital-based studies Nepal reported cases, with prevalence 2.48% 2010 to 4.47% 2019 emphasising on necessity of universal screening for Mellitus.Methods: As part implementation Electronic Decision support System Antenatal Care, formative study clinical vignettes case presented six healthcare providers ( Incharges, Auxiliary Nurse, Midwives Lab Assistants)...
<title>Abstract</title> Background Diabetes care incorporates multiple integrated elements like self-care practices, patient education and awareness, societal support, equitable access to healthcare facilities trained professionals, commitment from the diabetes associations government policies. There is a dearth of research viewing into barriers experienced by both People with Type 1 (PwT1D) 2 (PwT2D) in accessing holistic care. This study thus aims explore perspectives PwT1D PwT2D towards...
Background and objective: High blood pressure is a major risk factor for heart disease stroke. These diseases can be reduced if hypertension identified, managed controlled. Disease burden in Nepal high, resources are limited, the population socioeconomically vulnerable. Developing tailored interventions management requires understanding of challenges facilitators healthcare. This qualitative study investigated barriers impacting treatment control patients with rural Nepal. Methods: We...
Background: Atrial fibrillation (AF) is a common morbid arrhythmia that can cause thromboembolic events such as stroke. Despite advancements in diagnostic technologies, significant number of AF patients may remain undetected and undiagnosed, these asymptomatic possess sufficient risk cardioembolic Identifying through appropriate screening techniques timely initiation systemic anticoagulation therapy essential to prevent life‐threatening complications. Objectives: The objectives this study...