- Antibiotic Resistance in Bacteria
- Salmonella and Campylobacter epidemiology
- Bacterial Infections and Vaccines
- Antibiotic Use and Resistance
- Viral gastroenteritis research and epidemiology
- Urological Disorders and Treatments
- Vibrio bacteria research studies
- Listeria monocytogenes in Food Safety
- Reproductive tract infections research
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Hemoglobinopathies and Related Disorders
- Neonatal Health and Biochemistry
- Syphilis Diagnosis and Treatment
- Bacterial biofilms and quorum sensing
- Orthopaedic implants and arthroplasty
- Plant Pathogenic Bacteria Studies
- Food Safety and Hygiene
- Bacteriophages and microbial interactions
- Antimicrobial Resistance in Staphylococcus
- Genital Health and Disease
- Urologic and reproductive health conditions
- Male Reproductive Health Studies
- Infections and bacterial resistance
- Teacher Education and Leadership Studies
Tennessee Department of Health
2019-2024
Husch Blackwell LLP (United States)
2021
Duke University
2021
Emory University
2020
Duke Medical Center
2020
New York State College of Veterinary Medicine
2019
Cornell University
2019
Johnson C. Smith University
2010
North Carolina State University
2006
University of Wales
1995-1996
BackgroundThe number of cases gonorrhoea in the USA and worldwide caused by Neisseria gonorrhoeae is increasing (555 608 reported US 2017, 87 million 2016). Many countries report declining vitro susceptibility azithromycin, which a concern because azithromycin ceftriaxone are recommended dual treatment many countries. We aimed to identify strain types associated with decreased azithromycin.MethodsWe did genomic analysis N isolates obtained Gonococcal Isolate Surveillance Project. Isolates...
No AccessJournal of Urology1 Apr 1971Retrocaval Ureter: 4 Cases Thomas E. Shown and C.A. Moore ShownThomas MooreC.A. View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)61557-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1971 by The American Urological Association Education Research, Inc.FiguresReferencesRelatedDetailsCited byFernandes M, Scheuch J Seebode (2018) Horseshoe Kidney with Retrocaval A Case...
No AccessJournal of Urology1 Aug 1963One-Stage Repair Stricture Bulbous Urethra C.A. Moore MooreC.A. More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)64390-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail © 1963 The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByBARBAGLI G, PALMINTERI E RIZZO M (2018) DORSAL ONLAY GRAFT...
Campylobacteriosis is the most common bacterial foodborne illness in United States and frequently associated with foods of animal origin. The goals this study were to compare clinical non-clinical Campylobacter populations from Tennessee (TN) Pennsylvania (PA), use phylogenetic relatedness assess source attribution patterns, identify potential outbreak clusters. isolates studied (n = 3080) included TN collected sequenced for routine surveillance, PA patients at University Health System...
No AccessJournal of Urology1 Oct 1971Prednisone in the Treatment Acute Epididymitis: A Cooperative Study C.A. Moore, Bobby L. Lockett, Kenneth W. Lennox, Jack McAninch, John C. Wurster, Frank E. Ceccarelli, and Mauro P. Gangai MooreC.A. Moore Current address: Department Army, Headquarters, 65th Medical Group, APO San Francisco 96301. More articles by this author , LockettBobby Lockett LennoxKenneth Lennox McAninchJack McAninch WursterJohn Wurster CeccarelliFrank Ceccarelli GangaiMauro View...
Abstract Periprosthetic joint infection is a costly debilitating affliction following total arthroplasty. Despite relatively low incidence rate, periprosthetic an increasing problem due to substantial increase in arthroplasty surgeries over time. The current treatment replacing the primary implant with temporary bone cement spacer that releases antibiotics However, mechanically weak ineffective antibiotic release. Alternatively, three‐dimensional (3D)‐printed reservoirs high‐strength devices...
The recent emergence of strains Neisseria gonorrhoeae associated with treatment failures to ceftriaxone, the foundation current options, has raised concerns over a future untreatable gonorrhea. Current global data on gonococcal suggest that several lineages, predominately characterized by mosaic penA alleles, are elevated minimum inhibitory concentrations (MICs) extended spectrum cephalosporins (ESCs). Here we report whole genome sequences 813 N. isolates collected through Gonococcal Isolate...
Abstract Objective To determine the prognosis for racing of horses surgically treated slab fractures third carpal bone (C3). Study design Retrospective case study. Animals Horses (n = 125) C3 fractures. Methods Medical records dorsal or sagittal were reviewed age, sex, breed, limb, fracture type, degree cartilage damage, and surgical treatment. Radiographs evaluated to depth, width, displacement. Osteophytes, lysis, fragmentation scored. Racing performance was obtained from online databases....
In the United States, surveillance of norovirus gastroenteritis is largely restricted to outbreaks, limiting our knowledge contribution sporadic illness overall impact on reported outbreaks. Understanding transmission dynamics vital for improving preventive measures, including vaccine development.We analyzed seasonal patterns and genotypic distribution between pediatric cases outbreaks in middle Tennessee. Sporadic were ascertained via New Vaccine Surveillance Network a single county, while...
Abstract Neisseria gonorrhoeae multilocus sequence type (ST) 9363 core-genogroup isolates have been associated with reduced azithromycin susceptibility (AZMrs) and show evidence of clonal expansion in the United States. Here, we analyze a global collection ST-9363 genomes to shed light on emergence dissemination this strain. The population structure falls into three lineages: Basal, European, North American; 32 clades within all lineages. Although, is inferred originated from Asia mid-19th...
Abstract Background Contaminated healthcare facility wastewater plumbing is recognized as a source of carbapenemase-producing organism transmission. In August 2019, the Tennessee Department Health (TDH) identified patient colonized with Verona integron-encoded metallo-beta-lactamase-producing carbapenem-resistant Pseudomonas aeruginosa (VIM-CRPA). A record review revealed that 33% (4 12) all reported patients in VIM had history prior admission to acute care hospital (ACH) intensive unit...
No AccessJournal of Urology1 Mar 1965Surgical Repair Chordee Without Hypospadias: Report Three Cases C.A. Moore MooreC.A. More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)63784-4AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Surgical Cases." The Journal Urology, 93(3), pp. 389–390 © 1965 American Urological Association Education and Research,...
Combating single and multi-drug-resistant infections in the form of biofilms is an immediate challenge. The challenge to discover innovative targets develop novel chemistries that combat drug-resistant organisms, thwart emergence future resistant strains. An ideal target would control multiple genes, can be inhibited by a compound. We previously demonstrated success against Staphylococcus aureus targeting tRNA-dependent regulated T-box not present human host. Present Gram-positive bacteria,...
Carbapenem-resistant
To determine the biological significance of high concentrations non-haem iron in livers infants dying from sudden infant death syndrome (SIDS), liver samples were obtained at necropsy 66 who died SIDS and 28 control before 2.5 years age. All full term deliveries. Liver decreased rapidly with age two groups. controls compared for those between 1 month year The median concentration was 296 micrograms/g wet weight; significantly higher than 105 controls. There an inverse relation groups, but...
Salmonella enterica serovar Javiana is the fourth most reported of laboratory-confirmed human infections in U.S. and Tennessee (TN). Although ser. a common cause infection, majority cases are sporadic nature rather than outbreak-associated. To better understand microbial population structure TN, we completed phylogenetic analysis 111 clinical isolates from TN collected Jan. 2017 to Oct. 2018. We identified mobile genetic elements genes known confer antibiotic resistance present isolates,...
Liver iron concentrations have been shown to be higher in victims of SIDS than postmortem controls suggesting that high levels tissue may implicated SIDS. To determine whether infants who subsequently die from are born with greater stores those do not, the newborn were assessed retrospectively by measuring blood ferritin concentration spots Guthrie cards (collected almost all UK first week life). A method for extracting and stored is described. Eighteen cases identified South Glamorgan along...
AIMS--To confirm the observation of extremely high concentrations ferritin in postmortem serum samples sudden infant death syndrome (SIDS); to examine factors influencing blood postmortem; determine whether or not these are characteristic SIDS. METHODS--Postmortem cardiac were obtained from 58 full term infants who died SIDS and 14 full-term a variety other causes. Whole determined compared with age at death, liver iron concentration, lactate dehydrogenase activity. RESULTS--The median...