Marcelo Gonzaga de Freitas Araújo

ORCID: 0000-0002-6320-3185
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About
Contact & Profiles
Research Areas
  • Antifungal resistance and susceptibility
  • Essential Oils and Antimicrobial Activity
  • Reproductive tract infections research
  • Nail Diseases and Treatments
  • Phytochemistry Medicinal Plant Applications
  • Traditional and Medicinal Uses of Annonaceae
  • Ethnobotanical and Medicinal Plants Studies
  • Synthesis and biological activity
  • Phytochemical compounds biological activities
  • Advanced Drug Delivery Systems
  • Herbal Medicine Research Studies
  • Complementary and Alternative Medicine Studies
  • Seaweed-derived Bioactive Compounds
  • Bee Products Chemical Analysis
  • Curcumin's Biomedical Applications
  • Medical and Biological Ozone Research
  • Maternal and Neonatal Healthcare
  • Synthesis and Biological Evaluation
  • Phytochemistry and Biological Activities
  • Piperaceae Chemical and Biological Studies
  • Insects and Parasite Interactions
  • Fungal Infections and Studies
  • Phytochemical Studies and Bioactivities
  • Biochemical and Structural Characterization
  • Medication Adherence and Compliance

Federal University of São João del-Rei
2015-2025

Interface (United Kingdom)
2019

John Wiley & Sons (United States)
2017-2019

Hudson Institute
2017

Universidad Nacional de Córdoba
2017

Consejo Nacional de Investigaciones Científicas y Técnicas
2017

Universidade Estadual Paulista (Unesp)
2010-2012

Universidade de Franca
2011

Gastrointestinal diseases are very common problems; available treatments limited and come with a range of side effects. Coumarins an extensive class phenolic compounds that can be found in plants, fungi bacteria. The 7-hydroxycoumarin, also known as umbelliferone (UMB), is compound comes from coumarin has been showing biological activities other studies. As this scenario, the present study was designed to evaluate acute oral toxicity, mutagenic, antidiarrheal, anti-bacterial, antiulcerogenic...

10.1016/j.biopha.2020.110432 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2020-07-03

Herbal-loaded drug delivery nanotechnological systems have been extensively studied recently. The antimicrobial activity of medicinal plants has shown better pharmacological action when such are loaded into a system than they not loaded. Syngonanthus nitens Bong. (Rhul.) belongs to the Eriocaulaceae family and presents antiulcerogenic, antioxidant, antibacterial, antifungal activity. aim this study was evaluate (S. nitens) extract that (E) or (SE) liquid crystal precursor (S) for treatment...

10.3390/ijms17081368 article EN International Journal of Molecular Sciences 2016-08-22

Objetivo: Este estudo teve como objetivo investigar a perspectiva de pais/cuidadores crianças com Transtorno do Espectro Autista (TEA), no município Divinópolis, MG, Brasil, em relação aos tratamentos e acompanhamentos que suas recebem. Metodologia: Estudo qualitativo caráter descritivo, pais cuidadores TEA. Os dados foram analisados segundo metodologia análise conteúdo Bardin. Resultados: categorizados 4 temáticas centrais: sintomas, bem-estar, apoio geral. As manifestações comum dos...

10.33448/rsd-v14i3.48521 article PT Research Society and Development 2025-03-23

The biological activities of a plant extract depend on complex sum individual properties including the antioxidant activity. Several protect against harmful action reactive oxygen species (ROS), and here we focused our attention relationship between tested properties. In this study, total flavonoid content as well antioxidant, antimicrobial, hemolytic cytotoxicity methanolic Leitothrix spiralis leaves were evaluated. showed 19.26% chemical characterization by HPLC-PAD confirmed presence...

10.3390/ijms13079260 article EN International Journal of Molecular Sciences 2012-07-24

The purpose of this study was to evaluate the in vitro anticandidal activity a methanolic extract Syngonanthus nitens scapes against different Candida species and clinical isolates from patients with vulvovaginal candidiasis (VVC), its effect vivo treatment vaginal infection. Chemical characterization performed by HPLC-UV analyses showed presence flavones derivatives. effective several strains our collection recovered VVC patients, able inhibit yeast-hyphal transition. No cytotoxic human...

10.3109/13693786.2013.795294 article EN Medical Mycology 2013-06-13

Miconazole-loaded nanoparticles coated with hyaluronic acid (miconazole-loaded nanoparticles/HA) were developed to overcome the limitations of conventional therapy vulvovaginal candidiasis (VVC). They synthesized by emulsification and solvent evaporation techniques, characterized diameter, polydispersity index, zeta potential, encapsulation efficiency, atomic force microscopy (AFM), evaluated in terms efficacy against C. albicans vitro, tested a murine VVC model. Nanoparticles showed 211nm...

10.1016/j.ejps.2023.106508 article EN cc-by-nc-nd European Journal of Pharmaceutical Sciences 2023-06-26

Chemical fractionation of the methanolic extract leaves Leiothrix spiralis Ruhland afforded flavonoids luteolin-6-C-β-D-glucopyranoside (1), 7-methoxyluteolin-6-C-β-D-glucopyranoside (2), 7-methoxyluteolin-8-C-β-D-glucopyranoside (3), 4'-methoxyluteolin-6-C-β-D-glucopyranoside (4), and 6-hydroxy-7-methoxyluteolin (5), xanthones 8-carboxymethyl-1,5,6-trihydroxy-3-methoxyxanthone (6), 8-carboxy-methyl-1,3,5,6-tetrahydroxyxanthone (7). Methanolic extract, fractions, isolated compounds L. were...

10.3390/molecules161210479 article EN cc-by Molecules 2011-12-16

Vulvovaginal candidiasis (VVC) is characterized by inflammatory changes in the vaginal mucosa caused abnormal colonization of Candida species. Traditional topical therapies using reference antifungal drugs usually present several issues and limitations for VVC treatment. Thus, interest new formulations, mainly those based on compounds from natural origin, has been growing over last years. Methanolic extract plant species Mitracarpus frigidus (Willd. Ex Reem Schult.) K. Schum (MFM) presented...

10.1016/j.biopha.2020.110609 article EN Biomedicine & Pharmacotherapy 2020-08-14

Corrected by: Erratum for: Antimutagenic Potential of Solanum lycocarpum against Induction Chromosomal Aberrations in V79 Cells and Micronuclei Mice by DoxorubicinPlanta Med 2011; 77(13): E13-E13DOI: 10.1055/s-0031-1280192

10.1055/s-0030-1270886 article EN Planta Medica 2011-03-07

Summary Owing to the growing resistance among isolates of Candida species usual antifungal agents and well‐known therapeutic potential curcumin, purpose this study was develop validate a vaginal formulation containing substance evaluating its effectiveness in treatment experimental vulvovaginal candidiasis. Curcumin incorporated cream three concentrations (0.01%, 0.1% 1.0%). The different controls were intravaginally administered an immunosuppressed rat model evaluate efficacy Samples also...

10.1111/myc.12762 article EN Mycoses 2018-03-08

Frente ao aumento progressivo da prevalência de Diabetes Mellitus tipo 2 na população brasileira e elevada pacientes que utilizam a glibenclamida para tratamento dessa morbidade, esta comunicação breve possui como objetivo principal apresentar os riscos cardiovasculares hipoglicêmicos associados uso chamar atenção das Comissões Farmácia Terapêutica (CFT) dos municípios brasileiros avaliem relação risco/benefício padronização outra sulfoniluréia, visto grande parte Relações Municipais...

10.5216/ref.v11i4.32046 article PT Revista Eletrônica de Farmácia 2015-03-10
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