A5080191029- Traumatic Brain Injury and Neurovascular Disturbances
- Traumatic Brain Injury Research
- Functional Brain Connectivity Studies
- Neurosurgical Procedures and Complications
- Spinal Fractures and Fixation Techniques
- Cerebrospinal fluid and hydrocephalus
- Electrolyte and hormonal disorders
- Intracranial Aneurysms: Treatment and Complications
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cervical and Thoracic Myelopathy
- Simulation and Modeling Applications
- Technology Assessment and Management
- Intensive Care Unit Cognitive Disorders
- Heart Rate Variability and Autonomic Control
- Anesthesia and Neurotoxicity Research
- Cardiac, Anesthesia and Surgical Outcomes
- Psychosomatic Disorders and Their Treatments
- Pulsed Power Technology Applications
- Optimal Power Flow Distribution
- Medical Imaging and Analysis
- Intracerebral and Subarachnoid Hemorrhage Research
- Thermoregulation and physiological responses
- Neuroscience and Neuropharmacology Research
- Nosocomial Infections in ICU
- Delphi Technique in Research
China Academy Of Machinery Science & Technology (China)
2015-2023
Shanghai Tenth People's Hospital
2020
Huashan Hospital
2009-2016
Fudan University
2009-2015
Tianjin University of Traditional Chinese Medicine
2012-2013
Taizhou People's Hospital
2010
Nantong University
2010
For accurate diagnosis and prognostic prediction of acquired brain injury (ABI), it is crucial to understand the neurobiological mechanisms underlying loss consciousness. However, there no consensus on which regions networks act as biomarkers for consciousness level recovery outcome in ABI. Using resting-state fMRI, we assessed intrinsic functional connectivity strength (FCS) whole-brain a large sample 99 ABI patients with varying degrees (including fully preserved state, minimally conscious...
Objective We aimed to investigate the roles of different resting‐state networks in predicting both actual level consciousness and its recovery brain injury patients. Methods investigated functional connectivity within patients with varying levels consciousness: unresponsive wakefulness syndrome (UWS; n = 56), minimally conscious state (MCS; 29), lesions but full (BL; 48). Considering consciousness, we compared strength network among patient groups. then checked presence connections between...
Abstract Recent studies have demonstrated resting‐state abnormalities in midline regions vegetative state/unresponsive wakefulness syndrome and minimally conscious state patients. However, the functional implications of these remain unclear. findings healthy subjects revealed a close overlap between neural substrate self‐referential processing activity cortical regions. As such, we investigated task‐related during active various measures 11 patients with disorders consciousness (DOC) 12...
Objectives: To estimate the incidence of coagulopathy and disseminated intravascular coagulation (DIC) in patients with traumatic brain injury (TBI) to investigate its relationship patient outcome.
We retrospectively studied a random cohort of patients with cerebral trauma to investigate the risk factors acute kidney injury (AKI) following trauma. AKI was determined using RIFLE (risk, injury, failure, loss, or end-stage kidney) staging criteria. About 171 were chosen in study, 53 group and 118 without non-AKI group. By logistic regression analysis, univariate analysis revealed that age, hypertension, emergent surgery, systemic inflammatory response syndrome (SIRS), Glasgow coma score...
Little is known about the propensity for certain emotional stimuli, such as historically familiar pictures, to activate a large neural network in patients exhibiting minimally conscious state (MCS). A study was conducted nine MCS and 10 healthy control subjects explore degree which passive stimulation of pictures with different valences--intimate family (FPs), high-stimulating (HSPs), medium-stimulating (MSPs), all selected from International Affective Picture System (IAPS)--could elicit...
The role of brain natriuretic peptide (BNP) after traumatic injury (TBI) remains unclear, and its relationship with hyponatremia is still controversial. aim this study to investigate the secretion pattern N-terminal (NT)-proBNP in patients TBI assess between NT-proBNP, sodium balance, intracranial pressure (ICP).We measured serum NT-proBNP levels 84 isolated on a daily basis from day 1 14 injury.In average, peak BNP level was at 703.9 pg/mL±179.1 pg/mL 3 injury, which correlated severity...
Disorders of consciousness (DoC)-that is, unresponsive wakefulness syndrome/vegetative state and minimally conscious state-are debilitating conditions for which no reliable markers recovery have yet been identified. Evidence points to the GABAergic system being altered in DoC, making it a potential target as such marker.In our preliminary study, we used [(11) C]Flumazenil positron emission tomography establish global GABAA receptor binding values local-to-global (LTG) ratio these specific...
Background: Few studies have examined the acute exercise-induced changes in cognitive performance different thermal environments and time course effects. Objective: Investigate time-dependent effects of exercise on university students' processing speed, working memory flexibility temperate cold environments. Method: Twenty male students (age 23.5 ± 2.0 years) with moderate physical activity level participated a repeated-measures within-subjects design. Processing were assessed using CogState...
With the development of enteral nutrition in patients with neurological disorders China, related guidelines were published 2011. The Chinese Society for Parenteral and Enteral Nutrition conducted a survey to evaluate status quo practices these patients.This multicenter prospective investigation was from April 2012 2013 involved 18 tertiary hospitals China. using standardized questionnaires sought information about basic protocols (devices staffing) specific conditions who received by way...
To observe the effects of bloodletting puncture at Jing-Well points in distal ends finger and toe on survival rate, time, brain edema rats with cerebral ischemia. Fifty-four male Sprague-Dawley were randomly divided into five groups: normal, sham operation, model, toe, without these points. Middle artery occlusion models established according to Longa's method. The brains taken 48 h after model was established. Brain water content, density, coefficient, time each group measured. After...
A rat model of middle cerebral artery permanent occlusion was established using the modified Longa method. Successfully animals were treated by blood-letting puncture at twelve Jing-Well points hand, and/or injecting mannitol into caudal vein twice daily. Brain tissue collected 24, 48 and 72 hours after modeling, blood through retinal before Evans blue injected, approximately 1 hour prior to harvesting brain tissue. Results showed that leakage serum nitric oxide synthase activity...
Objectives To define the core competencies essential for specialist training in neurocritical care China. Design Modified Delphi method and nominal group (NG) technique. Setting National. Participants A total of 1094 respondents from 33 provinces China participated online survey. NG 11 members was organised by Neuro-Critical Care Committee affiliated with Chinese Association Critical Physicians National Center Healthcare Quality Management Neurological Diseases. Results formal list...
Architectural complexity analysis plays an important role in the design of complex systems and System Systems (SoS). In this process, a central problem is how to define indicator SoS level. This paper discusses preliminary study on architectural BRIDGE system, typical large-scale emergency rescue management system. The traditional definition complexity, which has been successfully used describe military SoS, not suited for case. consists multiplication several components indicators, does...
According to the needs of field chemical defence support simulation, this paper proposes a design method simulation software, and realizes corresponding software based on method. The includes initialization data receiving module, equipment command reconnaissance decontamination smoke fire spray module output recording is composed. Based method, problem can be solved.
Objective Primary testicular mucinous cystadenoma (PTMC) is one of the rarest ‘ovarian type’ tumors which originating from surface epithelium. We aimed to present a case was finally diagnosed as PTMC and try analysis clinical characteristics this condition.
Objective To summary and analyze the clinical characteristics acute phase prognosis of brain injury patients complicated by intracranial infection.Methods The data with infection confirmed cerebrospinal fluid culture in Huashan hospital trauma center during January 2008 to December 2012 were collected retrospectively analyzed.Risk factors Glasgow coma scale (GCS) at discharge,multiple microbial G-/G+ investigated.Results From there are 82 secondary injury.Total 97 bacterial strains...
The current study of the effectiveness and cost equipment system does not involve analysis from inception to formation optimization existing system. This paper presents an method system, which is based on cost-effectiveness analysis. First all, components be studied or formed are defined, number factors affecting determined, research methods data processing for each factor determined. Second, if influencing exceeds defined value, should screened. important were obtained by sensitivity...
At present, the methods to realize real-time transmission of ground information and data by remote fire command center plan artillery path with minimum cost have their own advantages. In order improve combat ability far-fire strike joint operation, a heuristic search algorithm far-fire, A <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">*</sup> planning algorithm, is proposed here. The Air Force acquired geographic area through sensing...
Objective To study causes of deterioration sudden mydriasis in craniocerebral trauma patients with normal intracranial pressure and verify the efficiency specific treatments.Methods A retrospective analysis was performed on four cases accidental among 473 treated from June 2008 to March 2012.Changes patients' condition monitoring indices were observed after treatments.Results Abnormal synchronously largely due sufficient decompression a certain period hypertension persistence brain perfusion...